{"product_id":"equine-herpesvirus-type-4-qpcr","title":"Equine Herpesvirus Type 4, qPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe\u003cstrong\u003e\u003cspan\u003e q\u003c\/span\u003ePCR test\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003e detects the\u003cspan\u003e \u003c\/span\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003cstrong\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eof  Equine Herpesvirus Type 4 (EHV-4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cem\u003eMolecular detection of EHV-4 by PCR is the most sensitive, specific and accurate tool in assessing the infectivity of an affected horse\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1 nasal or nasopharyngeal swab\u003c\/strong\u003e ( see\u003ca aria-describedby=\"a11y-external-message\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\" data-mce-href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\"\u003e AAEP guidelines)\u003c\/a\u003e \u003c\/li\u003e\n\u003cli\u003eand\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e5 mL - K3 EDTA tube\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e20 gr - placental or foetal tissue - sterile flask\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan style=\"color: #e8b80d;\" data-mce-style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 4?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine Herpesvirus Type 4 (EHV-4) is a health risk to equine populations worldwide. Disease severity depends on multiple factors and may be latent in normal horses. And because clinical signs are similar to other respiratory diseases, it is difficult to make a definitive diagnosis from clinical presentation alone.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEHV-4 infections are restricted to respiratory tract epithelium and associated lymph nodes,\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eInfection of pregnant mares with EHV-4 strains rarely results in abortion.\u003c\/li\u003e\n\u003cli\u003eLike EHV-1 the EHV-4 establish latent infection in the majority of horses, which do not show clinical signs but may experience reactivation of infection and shedding of the virus when stressed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEHV-4 spread via aerosolised secretions from infected coughing horses, by direct and indirect (fomite) contact with nasal secretions.\u003c\/li\u003e\n\u003cli\u003eThe most common way for EHV-4 to spread is by direct horse-to-horse contact.\u003c\/li\u003e\n\u003cli\u003eThis virus is shed from infected horses via the respiratory tract.\u003c\/li\u003e\n\u003cli\u003eHorses may appear to be perfectly healthy yet spread the virus via the secretions from their nostrils.\u003c\/li\u003e\n\u003cli\u003eIt is important to realize that EHV-4 can also be spread indirectly through contact with physical objects contaminated with infectious virus.\u003c\/li\u003e\n\u003cli\u003eThe air around a horse that is shedding the virus can also be contaminated with infectious virus.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eHerd elimination of equine herpesviruses is virtually impossible because of the pervasiveness of the carrier state.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDisease prevention, rather than treatment or attempts at eradication, offers the most effective means for controlling herpesvirus and its potential sequelae.\u003c\/li\u003e\n\u003cli\u003eStrategies aimed at reducing the economic and welfare impact associated with EHV-1 and EHV-4 respiratory infections include (1) prophylactic immunisation and (2) the implementation of preventive herd management practices.\u003c\/li\u003e\n\u003cli\u003eSubdivide horses into the small epidemiologically isolated closed groups.\u003c\/li\u003e\n\u003cli\u003eMinimize risks of exogenous and endogenous (stress induced viral reactivation) introduction of EHV-1.\u003c\/li\u003e\n\u003cli\u003eMaximize herd immunity through vaccination.\u003c\/li\u003e\n\u003cli\u003eImportant measures in the case of an EHV-4 outbreak:\u003c\/li\u003e\n\u003cli\u003eDisinfection of areas contaminated by virus from the aborted foetus and placental membranes.\u003c\/li\u003e\n\u003cli\u003eIsolation of affected horses.\u003c\/li\u003e\n\u003cli\u003eSubmission of clinical samples to a diagnostic laboratory.\u003c\/li\u003e\n\u003cli\u003eImplementation of hygienic procedures to prevent spread of infection (biosecurity).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29396168212524,"sku":"","price":55.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HEV-4.png?v=1571168218","url":"https:\/\/www.equigerminal.org\/ar\/products\/equine-herpesvirus-type-4-qpcr","provider":"Equigerminal","version":"1.0","type":"link"}