{"title":"Breeding \u0026 Reproduction","description":"\u003cp\u003eDiscover laboratory tests designed for mares, stallions and foals, including fertility assessments, pregnancy testing, reproductive health profiles and infectious disease screening to help optimise breeding success.\u003c\/p\u003e","products":[{"product_id":"stallion-profile-3-agents","title":"Breeding stallion profile","description":"\u003cp\u003e\u003cstrong\u003eBreeding s\u003cspan\u003etallion profile i\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003encludes \u003cstrong\u003e3\u003c\/strong\u003e\u003c\/span\u003e\u003cstrong\u003e accredited tests\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e:\u003c\/strong\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003eCoggins test for \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/equine-infectious-anemia-agid-coggins-t\"\u003eEquine Infectious Anemia (EIA)\u003c\/a\u003e,\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eAGID\u003c\/strong\u003e \u003cspan style=\"color: #e8b80d;\"\u003e(accredited test)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/equine-viral-arteritis-eva-rt-qpcr\"\u003eEquine Viral Arteritis (EVA\u003c\/a\u003e) test by\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eRT-qPCR\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/contagious-equine-metritis-organism-cemo-qpcr\"\u003eT\u003cem\u003eaylorella equigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003e(CEMO\u003c\/a\u003e),test by\u003cstrong\u003e qPCR\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 62.7224%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 20%;\"\u003e\u003cstrong\u003eTest\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSample type\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003e\u003cstrong\u003eCollection\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003e\n\u003cstrong\u003eVolume \u003c\/strong\u003e(mL)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 20%;\"\u003eCoggins test\u003c\/td\u003e\n\u003ctd style=\"width: 22%;\"\u003eSerum\/ Whole blood\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003eSerum tubes\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003e1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 20%;\"\u003eEVA PCR\u003c\/td\u003e\n\u003ctd style=\"width: 22%;\"\u003eEDTA blood\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003eK3 EDTA tube\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003e 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 20%;\"\u003eCEMO PCR\u003c\/td\u003e\n\u003ctd style=\"width: 22%;\"\u003e3 genital swabs (foreskin, urethra, glans fossa)\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003eSynthetic swab without media\u003c\/td\u003e\n\u003ctd style=\"width: 14.7224%;\"\u003eN.A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29391355707436,"sku":"","price":151.29,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Stallionprofile.png?v=1665065789"},{"product_id":"mare-profile-2-agents","title":"Breeding mare profile","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cstrong\u003e\u003cspan\u003e\u003cem\u003eBreeding mare Profile\u003c\/em\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e includes \u003cstrong\u003e2\u003c\/strong\u003e\u003c\/span\u003e\u003cstrong\u003e tests\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e:\u003c\/strong\u003e \u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003eCoggins Test \u003cspan style=\"color: #e8b80d;\"\u003e(accredited test for AIE)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e (CEMO) testing by qPCR\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements\u003cbr\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 70.341%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24%;\"\u003e\u003cstrong\u003eTest\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 27%;\"\u003e\u003cstrong\u003eSample type\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 19.4979%;\"\u003e\u003cstrong\u003eCollection\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 16.5021%;\"\u003e\n\u003cstrong\u003eVolume \u003c\/strong\u003e(mL)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24%;\"\u003eCoggins test\u003c\/td\u003e\n\u003ctd style=\"width: 27%;\"\u003eSerum\/ Whole blood\u003c\/td\u003e\n\u003ctd style=\"width: 19.4979%;\"\u003eSerum tubes\u003c\/td\u003e\n\u003ctd style=\"width: 16.5021%;\"\u003e1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24%;\"\u003eEVA PCR\u003c\/td\u003e\n\u003ctd style=\"width: 27%;\"\u003eEDTA blood\u003c\/td\u003e\n\u003ctd style=\"width: 19.4979%;\"\u003eK3 EDTA tube\u003c\/td\u003e\n\u003ctd style=\"width: 16.5021%;\"\u003e 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 24%;\"\u003eCEMO PCR\u003c\/td\u003e\n\u003ctd style=\"width: 27%;\"\u003e2 genital swabs: clitoral fossa and clitoral sinuses\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.4979%;\"\u003eSynthetic swab without media\u003c\/td\u003e\n\u003ctd style=\"width: 16.5021%;\"\u003eN.A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29391375630380,"sku":"","price":113.47,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Mareprofile.png?v=1665065790"},{"product_id":"equine-herpesvirus-type-1-1pcr","title":"Equine Herpesvirus Type 1, qPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe\u003cstrong\u003e qPCR test\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003e detects the\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cstrong\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eof  Equine Herpesvirus Type 1 (EHV-1).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1 nasal or nasopharyngeal swab\u003c\/strong\u003e ( see\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\" aria-describedby=\"a11y-external-message\" data-mce-href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\"\u003e AAEP guidelines)\u003c\/a\u003e \u003c\/li\u003e\n\u003cli\u003eand\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e5 mL - K3 EDTA tube\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - liquor (CSF) - sterile tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e24-48h - please contact lab\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003cmeta charset=\"UTF-8\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/inside.fei.org\/fei\/your-role\/veterinarians\/biosecurity-movements\/biosecurity\/testing-labs\"\u003e Our lab is approved by FEI for EHV-1 testing.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/inside.fei.org\/fei\/your-role\/veterinarians\/biosecurity-movements\/biosecurity\/testing-labs\"\u003e\u003cimg height=\"55\" width=\"103\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/1200px-FEI_Logo_RGB_Purple.svg_a1c2e1cd-e453-4940-bdd8-69689978c01f_480x480.png?v=1645556618\" alt=\"\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/1200px-FEI_Logo_RGB_Purple.svg_a1c2e1cd-e453-4940-bdd8-69689978c01f_480x480.png?v=1645556618\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 1?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEquine herpesvirus-1 (EHV-1) infection is ubiquitous in most horse populations throughout the world, and causes disease in horses and extensive economic losses through frequent outbreaks of respiratory disease, abortion, neonatal foal death, and myeloencephalopathy.\u003c\/li\u003e\n\u003cli\u003eInfections caused by EHV-1 are particularly common in young performance horses, and typically result in establishment of latent infection within the 1st weeks or months of life with subsequent viral reactivation causing clinical disease and viral shedding during periods of stress.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eRelevant effects of this virus on the equine population:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSporadic occurrence of mild respiratory disease associated with pyrexia, principally affecting horses under 2 years of age, can lead to interruptions in athletic training programs; this is economically the least important manifestation of EHV-1 disease.\u003c\/li\u003e\n\u003cli\u003eAbortion occurring during the 3rd trimester of pregnancy, results in important economic losses.\u003c\/li\u003e\n\u003cli\u003eOutbreaks of neurological disease (equine herpes myeloencephalopathy or EHM) cause suffering and loss of life and also lead to extensive movement restrictions, disrupting breeding or training schedules and causing management difficulties at training centers, race tracks, and horse events.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe most common way for EHV-1 to spread is by direct horse-to-horse contact.\u003c\/li\u003e\n\u003cli\u003eThis virus is shed from infected horses via the respiratory tract or through direct or indirect contact with an infected aborted foetus and fetal membranes.\u003c\/li\u003e\n\u003cli\u003eHorses may appear to be perfectly healthy yet spread the virus via the secretions from their nostrils.\u003c\/li\u003e\n\u003cli\u003eIt is important to realize that EHV-1 can also be spread indirectly through contact with physical objects contaminated with infectious virus.\u003c\/li\u003e\n\u003cli\u003eThe air around a horse that is shedding the virus can also be contaminated with infectious virus.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSubdivide horses into the small epidemiologically isolated closed groups.\u003c\/li\u003e\n\u003cli\u003eMinimize risks of exogenous and endogenous (stress- induced viral reactivation) introduction of EHV-1.\u003c\/li\u003e\n\u003cli\u003eMaximize herd immunity through vaccination.\u003c\/li\u003e\n\u003cli\u003eImportant measures in the case of an EHV-1 outbreak:\u003c\/li\u003e\n\u003cli\u003eDisinfection of areas contaminated by virus from the aborted foetus and placental membranes.\u003c\/li\u003e\n\u003cli\u003eIsolation of affected horses.\u003c\/li\u003e\n\u003cli\u003eSubmission of clinical samples to a diagnostic laboratory.\u003c\/li\u003e\n\u003cli\u003eImplementation of hygienic procedures to prevent spread of infection (biosecurity).\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29396136099884,"sku":"","price":55.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HEV-1.png?v=1571168270"},{"product_id":"equine-herpesvirus-type-4-qpcr","title":"Equine Herpesvirus Type 4, qPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe\u003cstrong\u003e\u003cspan\u003e q\u003c\/span\u003ePCR test\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003e detects the\u003cspan\u003e \u003c\/span\u003e\u003cspan style=\"text-decoration: underline;\" data-mce-style=\"text-decoration: underline;\"\u003e\u003cstrong\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eof  Equine Herpesvirus Type 4 (EHV-4).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cem\u003eMolecular detection of EHV-4 by PCR is the most sensitive, specific and accurate tool in assessing the infectivity of an affected horse\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1 nasal or nasopharyngeal swab\u003c\/strong\u003e ( see\u003ca aria-describedby=\"a11y-external-message\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\" data-mce-href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\"\u003e AAEP guidelines)\u003c\/a\u003e \u003c\/li\u003e\n\u003cli\u003eand\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e5 mL - K3 EDTA tube\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e20 gr - placental or foetal tissue - sterile flask\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan style=\"color: #e8b80d;\" data-mce-style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 4?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine Herpesvirus Type 4 (EHV-4) is a health risk to equine populations worldwide. Disease severity depends on multiple factors and may be latent in normal horses. And because clinical signs are similar to other respiratory diseases, it is difficult to make a definitive diagnosis from clinical presentation alone.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEHV-4 infections are restricted to respiratory tract epithelium and associated lymph nodes,\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eInfection of pregnant mares with EHV-4 strains rarely results in abortion.\u003c\/li\u003e\n\u003cli\u003eLike EHV-1 the EHV-4 establish latent infection in the majority of horses, which do not show clinical signs but may experience reactivation of infection and shedding of the virus when stressed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEHV-4 spread via aerosolised secretions from infected coughing horses, by direct and indirect (fomite) contact with nasal secretions.\u003c\/li\u003e\n\u003cli\u003eThe most common way for EHV-4 to spread is by direct horse-to-horse contact.\u003c\/li\u003e\n\u003cli\u003eThis virus is shed from infected horses via the respiratory tract.\u003c\/li\u003e\n\u003cli\u003eHorses may appear to be perfectly healthy yet spread the virus via the secretions from their nostrils.\u003c\/li\u003e\n\u003cli\u003eIt is important to realize that EHV-4 can also be spread indirectly through contact with physical objects contaminated with infectious virus.\u003c\/li\u003e\n\u003cli\u003eThe air around a horse that is shedding the virus can also be contaminated with infectious virus.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eHerd elimination of equine herpesviruses is virtually impossible because of the pervasiveness of the carrier state.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDisease prevention, rather than treatment or attempts at eradication, offers the most effective means for controlling herpesvirus and its potential sequelae.\u003c\/li\u003e\n\u003cli\u003eStrategies aimed at reducing the economic and welfare impact associated with EHV-1 and EHV-4 respiratory infections include (1) prophylactic immunisation and (2) the implementation of preventive herd management practices.\u003c\/li\u003e\n\u003cli\u003eSubdivide horses into the small epidemiologically isolated closed groups.\u003c\/li\u003e\n\u003cli\u003eMinimize risks of exogenous and endogenous (stress induced viral reactivation) introduction of EHV-1.\u003c\/li\u003e\n\u003cli\u003eMaximize herd immunity through vaccination.\u003c\/li\u003e\n\u003cli\u003eImportant measures in the case of an EHV-4 outbreak:\u003c\/li\u003e\n\u003cli\u003eDisinfection of areas contaminated by virus from the aborted foetus and placental membranes.\u003c\/li\u003e\n\u003cli\u003eIsolation of affected horses.\u003c\/li\u003e\n\u003cli\u003eSubmission of clinical samples to a diagnostic laboratory.\u003c\/li\u003e\n\u003cli\u003eImplementation of hygienic procedures to prevent spread of infection (biosecurity).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29396168212524,"sku":"","price":55.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HEV-4.png?v=1571168218"},{"product_id":"equine-coital-exanthema-qpcr","title":"Equine Coital Exanthema, qPCR","description":"\u003cp\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe qPCR test\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003e detects the\u003cspan\u003e \u003c\/span\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eof  \u003cem\u003eEquine Herpesvirus Type 3 \u003c\/em\u003e(EHV-3), the pathogen responsible for the Equine Coital Exanthema.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cem\u003eMolecular detection of EHV-3 by PCR is the most sensitive, specific and accurate tool in assessing the infectivity of an affected horse\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003cli\u003e1 genital swab - dry swab\u003c\/li\u003e\n\u003cli\u003e20 gr - placental or foetal tissue - sterile flask\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Equine Coital Exanthema?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan style=\"color: #ff00ff;\"\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003eEquine Herpesvirus type 3 (EHV-3) causes coital exanthema, a contagious genital infection (vulva in mares, penis and scrotum in stallions), spread venereally and characterised by numerous small blisters or spots, sometimes called ‘the pox’.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe clinical presentation of equine coital exanthema (ECE) is characterised by the presence of superficial lesions on the skin of the external genitalia of mares or stallions. The progress of each cutaneous lesion follows a well-defined and predictable course.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfection by EHV-3 occurs via direct cutaneous contact either during the act of coitus or by the transfer of virus-containing secretions from contaminated objects, such as hands, gloves, instruments, palpation sleeves, sponges and the lips or nose of a horse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe virus is easily transmitted by simple contact with the skin; the epidermal surface need not be damaged for infection to be established.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePrevention\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThere is no commercial vaccine against EHV-3.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eA stringent code of practice should be implemented within breeding sheds following observation of a case of ECE.\u003c\/li\u003e\n\u003cli\u003eThe three priorities necessary for successful ECE control are:\u003c\/li\u003e\n\u003cli\u003eCessation of breeding of clinically affected animals;\u003c\/li\u003e\n\u003cli\u003eHeightened vigilance on the part of personnel for early recognition of new clinical cases;\u003c\/li\u003e\n\u003cli\u003eStrict adherence to breeding shed hygiene procedures designed to eliminate mechanical transmission of the virus.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29396197769260,"sku":"","price":55.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/EHV-3.png?v=1571097120"},{"product_id":"equine-viral-arteritis-eva-elisa","title":"Equine Viral ArteritisELISA","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003eELISA test\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003edetects\u003cstrong\u003e \u003cspan style=\"text-decoration: underline;\"\u003eantibodies\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e to Equine Viral Arteritis (EVA) virus.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - serum tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Equine Viral Arteritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine viral arteritis (EVA) is an economically important viral disease of equids.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eStallions can become long term carriers of the virus, and transmit it during breeding. Although carrier stallions can be bred if precautions are taken, the need to mate them with seropositive or vaccinated mares decreases their desirability as breeders.\u003c\/li\u003e\n\u003cli\u003eAcute illness also occurs in some horses. Although deaths are very rare in healthy adults, pregnant mares that become infected may abort, and very young foals may die of fulminating pneumonia and enteritis. Equine viral arteritis has recently increased in prevalence, possibly due to increased transportation of horses and semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMost EAV infections, especially those that occur in mares bred to long-term carriers, are asymptomatic.\u003c\/li\u003e\n\u003cli\u003eThe clinical signs are generally more severe in old or very young animals, and in horses that are immunocompromised or in poor condition.\u003c\/li\u003e\n\u003cli\u003eFulminant infections with severe interstitial pneumonia and\/ or enteritis can be seen in foals up to a few months of age.\u003c\/li\u003e\n\u003cli\u003eSystemic illness also occurs in some adults. In adult horses, the clinical signs may include fever, depression, anorexia, limb edema (particularly in the hindlimbs), and dependent edema of the prepuce, scrotum, mammary gland and\/or ventral body wall.\u003c\/li\u003e\n\u003cli\u003eConjunctivitis, photophobia, periorbital or supraorbital edema and rhinitis can also be seen.\u003c\/li\u003e\n\u003cli\u003eAbortions or stillbirths can occur in mares that are pregnant when they are exposed. Abortions are not necessarily preceded by systemic signs.\u003c\/li\u003e\n\u003cli\u003eTemporary decreases in fertility, including reduced quality sperm and decreased libido, may be seen in stallions during the acute stage of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine Arteritis Virus (EAV) can be transmitted by the respiratory and the venereal routes.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eAcutely affected horses excrete the virus in respiratory secretions; aerosol transmission is common when horses are gathered at racetracks, sales, shows and other events.\u003c\/li\u003e\n\u003cli\u003eThis virus has also been found in urine and feces during the acute stage.\u003c\/li\u003e\n\u003cli\u003eIt occurs in the reproductive tract of acutely infected mares, and both acutely and chronically infected stallions.\u003c\/li\u003e\n\u003cli\u003eIn mares, EAV can be found in vaginal and uterine secretions, as well as in the ovary and oviduct, for a short period after infection.\u003c\/li\u003e\n\u003cli\u003eMares infected late in pregnancy may give birth to infected foals.\u003c\/li\u003e\n\u003cli\u003eStallions shed EAV in semen, and can carry the virus for years. Transmission from stallions can occur by natural service or artificial insemination.\u003c\/li\u003e\n\u003cli\u003eSome carriers may eventually clear the infection.\u003c\/li\u003e\n\u003cli\u003eTrue carrier states have not been reported in mares, geldings or sexually immature colts; however, EAV can occasionally be found for up to six months in the reproductive tract of older prepubertal colts.\u003c\/li\u003e\n\u003cli\u003eEquine arteritis virus can be transmitted on fomites including equipment, and may be spread mechanically by humans or animals.\u003c\/li\u003e\n\u003cli\u003eSemen remains infectious after freezing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAcutely infected horses should be isolated to prevent transmission in secretions and excretions.\u003c\/li\u003e\n\u003cli\u003ePrecautions should also be taken to avoid spreading the virus on fomites.\u003c\/li\u003e\n\u003cli\u003eEAV is readily inactivated by detergents, common disinfectants and lipid solvents.\u003c\/li\u003e\n\u003cli\u003eNo specific treatment is available; however, most healthy horses other than young foals recover on their own.\u003c\/li\u003e\n\u003cli\u003eGood nursing and symptomatic treatment should be used in severe cases.\u003c\/li\u003e\n\u003cli\u003eVaccination can also help contain outbreaks.\u003c\/li\u003e\n\u003cli\u003eVenereal transmission can be controlled by good management and vaccination.\u003c\/li\u003e\n\u003cli\u003eTo protect pregnant mares from abortion, they should be separated from other horses and maintained in small groups according to their predicted foaling dates.\u003c\/li\u003e\n\u003cli\u003eNewly acquired horses should be isolated for 3 to 4 weeks.\u003c\/li\u003e\n\u003cli\u003eVaccination appears to prevent uninfected stallions from becoming long term carriers.\u003c\/li\u003e\n\u003cli\u003eStallions that are not carriers should be vaccinated before the start of the breeding season.\u003c\/li\u003e\n\u003cli\u003ePrepubertal colts are given the vaccine when they are 6-12 months old.\u003c\/li\u003e\n\u003cli\u003eCarrier stallions are identified and bred only to well vaccinated or naturally seropositive mares.\u003c\/li\u003e\n\u003cli\u003eSimilarly, semen that contains EAV should be used only in these mares.\u003c\/li\u003e\n\u003cli\u003eBecause first-time vaccinates may shed field viruses for a short time after exposure, these mares should be isolated from seronegative horses, particularly pregnant mares, for three weeks after breeding.\u003c\/li\u003e\n\u003cli\u003eNaturally infected mares and those that are not first-time vaccinates are isolated for 24-48 hours, to protect other horses from the viruses present in semen.\u003c\/li\u003e\n\u003cli\u003eCarrier stallions should be housed where they can be physically separated from uninfected horses; in one case, stallions apparently became infected by indirect exposure to semen. However, this appears to be rare.\u003c\/li\u003e\n\u003cli\u003eEAV is sensitive to sunlight and low humidity, and uninfected stallions have been kept near carriers for years without infection.\u003c\/li\u003e\n\u003cli\u003eExcellent hygiene and decontamination of fomites should be practiced when breeding infected horses or collecting semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397195292716,"sku":"","price":43.27,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/EVA_ELISA.png?v=1571166984"},{"product_id":"equine-viral-arteritis-eva-rt-qpcr","title":"Equine Viral Arteritis RTqPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis\u003cstrong\u003e\u003cspan\u003e RT-qPCR\u003c\/span\u003e test\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003edetects\u003cstrong\u003e \u003c\/strong\u003ethe\u003cstrong\u003e\u003cspan style=\"text-decoration: underline;\"\u003e genome (RNA)\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e to Equine Viral Arteritis (EVA) virus.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA blood\u003c\/li\u003e\n\u003cli\u003e10 mL - semen - sterile tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Equine Viral Arteritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine viral arteritis (EVA) is an economically important viral disease of equids.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eStallions can become long term carriers of the virus, and transmit it during breeding. Although carrier stallions can be bred if precautions are taken, the need to mate them with seropositive or vaccinated mares decreases their desirability as breeders.\u003c\/li\u003e\n\u003cli\u003eAcute illness also occurs in some horses. Although deaths are very rare in healthy adults, pregnant mares that become infected may abort, and very young foals may die of fulminating pneumonia and enteritis. Equine viral arteritis has recently increased in prevalence, possibly due to increased transportation of horses and semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMost EAV infections, especially those that occur in mares bred to long-term carriers, are asymptomatic.\u003c\/li\u003e\n\u003cli\u003eThe clinical signs are generally more severe in old or very young animals, and in horses that are immunocompromised or in poor condition.\u003c\/li\u003e\n\u003cli\u003eFulminant infections with severe interstitial pneumonia and\/ or enteritis can be seen in foals up to a few months of age.\u003c\/li\u003e\n\u003cli\u003eSystemic illness also occurs in some adults. In adult horses, the clinical signs may include fever, depression, anorexia, limb edema (particularly in the hindlimbs), and dependent edema of the prepuce, scrotum, mammary gland and\/or ventral body wall.\u003c\/li\u003e\n\u003cli\u003eConjunctivitis, photophobia, periorbital or supraorbital edema and rhinitis can also be seen.\u003c\/li\u003e\n\u003cli\u003eAbortions or stillbirths can occur in mares that are pregnant when they are exposed. Abortions are not necessarily preceded by systemic signs.\u003c\/li\u003e\n\u003cli\u003eTemporary decreases in fertility, including reduced quality sperm and decreased libido, may be seen in stallions during the acute stage of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine Arteritis Virus (EAV) can be transmitted by the respiratory and the venereal routes.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eAcutely affected horses excrete the virus in respiratory secretions; aerosol transmission is common when horses are gathered at racetracks, sales, shows and other events.\u003c\/li\u003e\n\u003cli\u003eThis virus has also been found in urine and feces during the acute stage.\u003c\/li\u003e\n\u003cli\u003eIt occurs in the reproductive tract of acutely infected mares, and both acutely and chronically infected stallions.\u003c\/li\u003e\n\u003cli\u003eIn mares, EAV can be found in vaginal and uterine secretions, as well as in the ovary and oviduct, for a short period after infection.\u003c\/li\u003e\n\u003cli\u003eMares infected late in pregnancy may give birth to infected foals.\u003c\/li\u003e\n\u003cli\u003eStallions shed EAV in semen, and can carry the virus for years. Transmission from stallions can occur by natural service or artificial insemination.\u003c\/li\u003e\n\u003cli\u003eSome carriers may eventually clear the infection.\u003c\/li\u003e\n\u003cli\u003eTrue carrier states have not been reported in mares, geldings or sexually immature colts; however, EAV can occasionally be found for up to six months in the reproductive tract of older prepubertal colts.\u003c\/li\u003e\n\u003cli\u003eEquine arteritis virus can be transmitted on fomites including equipment, and may be spread mechanically by humans or animals.\u003c\/li\u003e\n\u003cli\u003eSemen remains infectious after freezing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAcutely infected horses should be isolated to prevent transmission in secretions and excretions.\u003c\/li\u003e\n\u003cli\u003ePrecautions should also be taken to avoid spreading the virus on fomites.\u003c\/li\u003e\n\u003cli\u003eEAV is readily inactivated by detergents, common disinfectants and lipid solvents.\u003c\/li\u003e\n\u003cli\u003eNo specific treatment is available; however, most healthy horses other than young foals recover on their own.\u003c\/li\u003e\n\u003cli\u003eGood nursing and symptomatic treatment should be used in severe cases.\u003c\/li\u003e\n\u003cli\u003eVaccination can also help contain outbreaks.\u003c\/li\u003e\n\u003cli\u003eVenereal transmission can be controlled by good management and vaccination.\u003c\/li\u003e\n\u003cli\u003eTo protect pregnant mares from abortion, they should be separated from other horses and maintained in small groups according to their predicted foaling dates.\u003c\/li\u003e\n\u003cli\u003eNewly acquired horses should be isolated for 3 to 4 weeks.\u003c\/li\u003e\n\u003cli\u003eVaccination appears to prevent uninfected stallions from becoming long term carriers.\u003c\/li\u003e\n\u003cli\u003eStallions that are not carriers should be vaccinated before the start of the breeding season.\u003c\/li\u003e\n\u003cli\u003ePrepubertal colts are given the vaccine when they are 6-12 months old.\u003c\/li\u003e\n\u003cli\u003eCarrier stallions are identified and bred only to well vaccinated or naturally seropositive mares.\u003c\/li\u003e\n\u003cli\u003eSimilarly, semen that contains EAV should be used only in these mares.\u003c\/li\u003e\n\u003cli\u003eBecause first-time vaccinates may shed field viruses for a short time after exposure, these mares should be isolated from seronegative horses, particularly pregnant mares, for three weeks after breeding.\u003c\/li\u003e\n\u003cli\u003eNaturally infected mares and those that are not first-time vaccinates are isolated for 24-48 hours, to protect other horses from the viruses present in semen.\u003c\/li\u003e\n\u003cli\u003eCarrier stallions should be housed where they can be physically separated from uninfected horses; in one case, stallions apparently became infected by indirect exposure to semen. However, this appears to be rare.\u003c\/li\u003e\n\u003cli\u003eEAV is sensitive to sunlight and low humidity, and uninfected stallions have been kept near carriers for years without infection.\u003c\/li\u003e\n\u003cli\u003eExcellent hygiene and decontamination of fomites should be practiced when breeding infected horses or collecting semen.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397208596524,"sku":"","price":61.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/EVA_RT-qPCR.png?v=1571167008"},{"product_id":"contagious-equine-metritis-organism-cemo-qpcr","title":"Contagious Equine Metritis Organism (CEMO), qPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis\u003cstrong\u003e\u003cspan\u003e PCR\u003c\/span\u003e test\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003edetects\u003cstrong\u003e \u003c\/strong\u003ethe\u003cstrong\u003e genome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e of \u003cem\u003eTaylorella equigenitalis \u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003ethe most comum bacteria responsible for the\u003cstrong\u003e\u003cspan\u003e \u003c\/span\u003eContagious Equine Metritis.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e3 genital swabs - swab Amies transport with charcoal.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa\u003c\/em\u003e \u003c\/strong\u003e– use standard swab with Amies culture and transport system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swabbed – use Minitip Amies culture and transport system. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\" data-mce-style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efrom a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eequigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ein the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003euntil results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eare detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397235531820,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/T._equigenitalis_qPCR.png?v=1665065819"},{"product_id":"contagious-equine-metritis-organism-cemo-culture","title":"Contagious Equine Metritis Organism - CEMO,  7d culture","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003ePathogen test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eculture test\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003edetects the presence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e\u003ci\u003e, \u003c\/i\u003ethe most comum bacteria responsible for the\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eContagious Equine Metritis.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e3 genital swabs - swab Amies transport with charcoal.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa\u003c\/em\u003e \u003c\/strong\u003e– use standard swab with Amies culture and transport system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swabbed – use Minitip Amies culture and transport system. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eNOTE: Schedule all CEM culture submissions in advance with the laboratory. Multiple culture instances are often required and timing is critical. Official CEM testing generally involves multiple sets of samples taken on multiple days. Exact sampling schedules need to be confirmed with appropriate regulatory agencies in advance of testing. Horses cannot be tested while being treated and for a period of time after treatment with antibiotics.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e7  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efrom a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eequigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ein the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003euntil results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eare detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397245591596,"sku":"","price":92.25,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/T._equigenitalis_Culture_7d.png?v=1665065819"},{"product_id":"contagious-equine-metritis-organism-cemo-culture-14-days","title":"Contagious Equine Metritis Organism (CEMO), 14d Culture","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eThis culture test detects the presence \u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e by culturing, the most common bacteria responsible for the Contagious Equine Metritis.\u003c\/p\u003e\n\u003cstrong style=\"font-size: 1.4em;\"\u003e\u003c\/strong\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e2 or 3 genital swabs - swab Amies transport with charcoal.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa\u003c\/em\u003e \u003c\/strong\u003e– use standard swab with Amies culture and transport system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swabbed – use Minitip Amies culture and transport system. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eNOTE: Schedule all CEM culture submissions in advance with the laboratory. Multiple culture instances are often required and timing is critical. Official CEM testing generally involves multiple sets of samples taken on multiple days. Exact sampling schedules need to be confirmed with appropriate regulatory agencies in advance of testing. Horses cannot be tested while being treated and for a period of time after treatment with antibiotics.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e14  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efrom a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eequigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ein the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003euntil results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eare detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397256732716,"sku":"","price":98.4,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/T._equigenitalis_Culture_14d.png?v=1665065817"},{"product_id":"contagious-equine-metritis-cem-qpcr","title":"Contagious Equine Metritis (CEM), qPCR","description":"\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eScreening of 3\u003cstrong\u003e pathogens\u003c\/strong\u003e responsible \u003cstrong\u003eContagious Equine Metritis\u003c\/strong\u003e (CEM): \u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eTaylorella equigenitalis,\u003c\/em\u003e\u003cb\u003e qPCR\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePseudomonas aeruginosa\u003c\/em\u003e,\u003cb\u003e\u003cspan\u003e \u003c\/span\u003eqPCR\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eKlebsiela pneumonia\u003c\/em\u003e,\u003cb\u003e\u003cspan\u003e \u003c\/span\u003eqPCR\u003c\/b\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e2 or 3 genital swabs -  use standard swab in dry swabs or transport media for molecular biology\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa \u003c\/em\u003e\u003c\/strong\u003e\u003cem\u003eswab\u003c\/em\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli style=\"list-style-type: none;\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swab. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efrom a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eequigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ein the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003euntil results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eare detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397301985324,"sku":"","price":99.3,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/CEM_3_Pathogens_qPCR.png?v=1665065816"},{"product_id":"contagious-equine-metritis-cem-culture-7-days","title":"Contagious Equine Metritis (CEM), 7d Culture","description":"\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003eScreening of 3\u003cstrong\u003e pathogens\u003c\/strong\u003e responsible for \u003cstrong\u003eContagious Equine Metritis\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e(CEM):\u003cbr\u003e\u003c\/p\u003e\n\u003cli\u003e\n\u003cem\u003eTaylorella equigenitalis by\u003c\/em\u003e\u003cb\u003e Culture over 7 days\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePseudomonas aeruginosa\u003c\/em\u003e,\u003cb\u003e\u003cspan\u003e \u003c\/span\u003eCulture \u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eKlebsiela pneumonia\u003c\/em\u003e,\u003cb\u003e\u003cspan\u003e \u003c\/span\u003eCulture\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e2 or 3 genital swabs in swab Amies transport medium with charcoal.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa\u003c\/em\u003e \u003c\/strong\u003e– use standard swab with Amies culture and transport system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swabbed – use Minitip Amies culture and transport system. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eNOTE: Schedule all CEM culture submissions in advance with the laboratory. Multiple culture instances are often required and timing is critical. Official CEM testing generally involves multiple sets of samples taken on multiple days. Exact sampling schedules need to be confirmed with appropriate regulatory agencies in advance of testing. Horses cannot be tested while being treated and for a period of time after treatment with antibiotics.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e7  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\" data-mce-style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003efrom a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eequigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003ein the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003euntil results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eequigenitalis\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eare detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397311488044,"sku":"","price":90.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/CEM_3_Pathogens_7d.png?v=1665065814"},{"product_id":"contagious-equine-metritis-cem-culture-14-days","title":"Contagious Equine Metritis (CEM), 14d Culture","description":"\u003cp\u003eScreening of 3\u003cstrong\u003e pathogens\u003c\/strong\u003e responsible for \u003cstrong\u003eContagious Equine Metritis\u003c\/strong\u003e (CEM):\u003cbr\u003e\u003c\/p\u003e\n\u003cli\u003e\n\u003cem\u003eTaylorella equigenitalis by c\u003c\/em\u003e\u003cb\u003eulture over 14 days\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePseudomonas aeruginosa by\u003c\/em\u003e\u003cb\u003e culture \u003c\/b\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eKlebsiela pneumonia by\u003c\/em\u003e\u003cb\u003e culture\u003c\/b\u003e\n\u003c\/li\u003e\n\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e2 or 3 genital swabs in Amies transport  medium with charcoal.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cem\u003eClitoral fossa\u003c\/em\u003e \u003c\/strong\u003e– use standard swab with Amies culture and transport system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eClitoral sinuses\u003c\/strong\u003e swabbed – use Minitip Amies culture and transport system. Openings to the sinuses are on the dorsum of the clitoris - the central one is usually always present whereas the lateral sinuses may be multiple or not be present. Swab all that are present.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eEither \u003cstrong\u003e\u003cem\u003ecervical\u003c\/em\u003e\u003c\/strong\u003e (closed cervix if pregnant or mid-cycle) or \u003cem\u003e\u003cstrong\u003eendometrial\u003c\/strong\u003e \u003c\/em\u003e(while in estrus or true anestrus) swab – use guarded 25” swab.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eNOTE: Schedule all CEM culture submissions in advance with the laboratory. Multiple culture instances are often required and timing is critical. Official CEM testing generally involves multiple sets of samples taken on multiple days. Exact sampling schedules need to be confirmed with appropriate regulatory agencies in advance of testing. Horses cannot be tested while being treated and for a period of time after treatment with antibiotics.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e14  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Contagious Equine Metritis?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eContagious equine metritis is an inflammatory disease of the proximal and distal reproductive tract of the mare caused by \u003cem\u003eTaylorella equigenitalis\u003c\/em\u003e, which usually results in temporary infertility. It is a nonsystemic infection, the effects of which are restricted to the reproductive tract of the mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical signs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eWhen present, general clinical signs include endometritis, cervicitis and vaginitis of variable severity and a slight to copious mucopurulent vaginal discharge.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eIn mares there are two states of infection:\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eThe active state\u003c\/strong\u003e in which the main outward sign is a vulval discharge, which may range from very mild to extremely profuse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThe carrier state\u003c\/strong\u003e in which there are no outward signs of infection. However, the mare remains capable of transmitting infection because the bacteria are established on the surface of the clitoris, the clitoral fossa and sinuses and, in the case of pneumoniae and \u003cem\u003eP. aeruginosa\u003c\/em\u003e, sometimes in the urethra and bladder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eI\u003cem\u003en stallions: (‘stallion’ means mating stallions, teasers and stallions used for AI)\u003c\/em\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eInfected stallions do not usually show clinical signs of infection but the bacteria are present on their penis, sheath and. These stallions can infect mares during mating, teasing or AI.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOccasionally, the bacteria may invade the stallion’s sex glands, causing pus and bacteria to contaminate the semen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eDirect venereal contact during natural mating presents the highest risk for the transmission of \u003cem\u003eequigenitalis\u003c\/em\u003e from a contaminated stallion or an infected mare.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eDirect venereal transmission can also take place by artificial insemination using infective raw, chilled and possibly frozen semen.\u003c\/li\u003e\n\u003cli\u003eIndirectly, infection may be acquired through fomite transmission, manual contamination, inadequate observance of appropriate biosecurity measures at the time of breeding and at semen- collection centres. Stallions can become asymptomatic carriers of\u003cem\u003e equigenitalis\u003c\/em\u003e.\u003c\/li\u003e\n\u003cli\u003eThe principal sites of colonisation by the bacterium are the urogenital membranes (urethral fossa, urethral sinus, terminal urethra and penile sheath).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe sites of persistence of \u003cem\u003eequigenitalis\u003c\/em\u003e in the majority of carrier mares are the clitoral sinuses and fossa and infrequently the uterus.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eFoals born of carrier mares may also become carriers.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe organism can infect equid species other than horses, e.g. donkeys.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIf infection with \u003cem\u003eequigenitalis\u003c\/em\u003e is suspected in any mare, stallion or teaser on the basis of clinical signs, all breeding activities must cease immediately.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe affected horse(s) should be isolated and swabbed by the attending veterinary surgeon.\u003c\/li\u003e\n\u003cli\u003eArrange swabbing of any at risk horse.\u003c\/li\u003e\n\u003cli\u003eDisinfect all equipment used for breeding procedures.\u003c\/li\u003e\n\u003cli\u003eInform all owners of mares booked to the stallion, including any which have already left the premises;\u003c\/li\u003e\n\u003cli\u003eInform people to whom semen from the stallion has been sent;\u003c\/li\u003e\n\u003cli\u003eArrange for one straw from every ejaculate of stored semen from infected and at risk stallions to be tested by a laboratory. If a straw from any ejaculate is infected, all straws from that ejaculate should be destroyed;\u003c\/li\u003e\n\u003cli\u003eAny at risk pregnant mare must be foaled in isolation. The placenta must be incinerated. Foals born to these mares should be swabbed three times, at intervals of not less than seven days, before three months of age.\u003c\/li\u003e\n\u003cli\u003eAny mares with an abnormal vaginal exudate, or returning to oestrus prematurely, should be investigated and managed as though infected with \u003cem\u003eequigenitalis\u003c\/em\u003e until results of laboratory testing prove otherwise.\u003c\/li\u003e\n\u003cli\u003eIf carriers of \u003cem\u003eequigenitalis\u003c\/em\u003e are detected, the organism can be eliminated by treatment with systemic and\/or local antibiotics combined with antiseptic washing of the sites of persistence in the mare and the stallion.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29397322629164,"sku":"","price":100.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/CEM_3_Pathogens_14d.png?v=1571150667"},{"product_id":"lethal-white-foal-syndrome-lwfs-qpcr","title":"LWFS Lethal White Foal Syndrome","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Overo gene that is associated with the Lethal White Foal Syndrome (LWFS).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\nor\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe relationship between Lethal White Foal Syndrome (LWFS) and the frame overo coat pattern is not always straightforward. Usually carriers of LWFS are frame overo in pattern, and have 1 copy of the mutated allele (nL). But not all frame overo horses carry the mutated allele, some have the genotype (nn).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eAnd some horses with other coat patterns (including solid coloured paints and tobiano) have been found to carry the mutated allele.\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIt should also be remembered that not all white foals have the genotype (LL) ,and may not be affected by LWFS.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the mutation associated to the Overo and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e \u003cb\u003eN\/\u003c\/b\u003e\u003c\/span\u003e – \u003cstrong\u003eNon-Overo\u003c\/strong\u003e or ‘solid’ horse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eO\/N\u003c\/b\u003e – \u003cstrong\u003eFrame Overo\u003c\/strong\u003e horse. Horse carries just a single copy of frame Overo. Since frame Overo is a dominant gene, the coat pattern should be present in all horses with a single copy of the mutated gene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eO\/\u003c\/strong\u003e – A \u003cstrong\u003eLethal White Foal Syndrome\u003c\/strong\u003e (LWFS). Foal carries two copies, homozygous for frame Overo. Since no living frame Overo horse more than a week old will test as being homozygous, it applies only to horses in the Lethal White condition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo is a highly desirable white pattern gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll Frame Overo horses carry a single inherited copy of the Ile118Lys EDNRB mutation. This mutation causes pigment loss, producing white markings on certain areas of the horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eWhile the mutation produces visually desirable horses, it is also linked to a fatal condition known as Lethal White Foal Syndrome (LWFS), whereby a foal is born almost pure white in appearance, and dies within its first few days of life. Correct breeding can avoid this occurrence.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003cspan class=\"s1\"\u003eLWFS occurs when a horse inherits two copies of the mutated gene, one from both parents. Whereas horses with just one copy of the gene will live normally and exhibit the desirable pattern. A horse with two copies of the mutated gene will suffer intestinal abnormalities caused by undeveloped nerves of the foal’s digestive system. These animals die within the first 72 hours of being born and are typically euthanized sooner for humane reasons.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo horses which carry just a single copy of the gene, will pass one copy of it to their foals approximately 50% of the time when bred.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTherefore, when breeding an Overo horse to a solid non-Overo horse, the foal can only inherit one copy. However, if two Overo horses are bred together they could potentially both pass the Overo gene to the foal, meaning it inherits two copies. Horses which inherit two copies of Frame Overo will suffer the Lethal White condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eProper mating must be carried out to ensure that two frame Overo horses do not breed. This will prevent any risk of the foal inheriting two copies of the mutated gene.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435113340972,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/LethalWhiteFoalSyndrome.png?v=1662540405"},{"product_id":"lavander-foal-syndrome-lfs-qpcr","title":"LFS Lavender Foal Syndrome","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Lavender Foal Syndrome (LFS) – Pure and part-bred Arab horses. This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e test verifies the presence of the recessive LFS gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis genetic test determines LFS clear, carrier or affected status. Informed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive LFS gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e N\/\u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003c\/strong\u003e–\u003cstrong\u003e Non-carrier\u003c\/strong\u003e of the LFS gene. Tested negative for the LFS gene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/LFS\u003c\/strong\u003e - \u003cstrong\u003eHeterozygous\u003c\/strong\u003e horse for LFS, both the normal and LFS alleles were detected. The horse is a carrier of LFS genetic disorder and there is a 50% chance this horse will pass a LFS allele to its offspring\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLFS\/\u003c\/strong\u003e – \u003cstrong\u003eHomozygous\u003c\/strong\u003e horse for LFS, carrier of two copies of the LFS gene. The horse is affected with the LFS genetic disorder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eLavender Foal Syndrome (LFS) is a recessive genetic disorder.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAffected foals born with the unique diluted coat color that can appear to be pale lavender, pale pink or silver. This foals-often have a difficult delivery, problems standing at birth and usually have episodes where they rigidly extend their limbs, neck and back. These episodes tend to resemble a seizure, although the affected foal does not seem normal between episodes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll affected foals are usually euthanised within days or weeks of birth.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eLFS is rare and is considered to be an autosomal recessive trait. “Autosomal” means that there is no sex linkage, so both males and females can be equally affected. “Recessive” means that in order for a foal to be affected, it must have received two copies of the mutated gene, inheriting one copy from each parent.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses that have one copy of the mutated gene, in combination with one copy of the normal gene, are physically normal but are considered carriers and have a 50% probability, each time they are bred, of passing the mutation along to their offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe SNP mutation that causes LFS has not been detected in other breeds.\u003c\/span\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTesting for this mutation in horses with no Arabian blood lines is not recommended. However, in cases where pedigree is not known, testing could be a useful tool to prevent possible affected foals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435115274284,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Lavander_Foal.png?v=1571095199"},{"product_id":"warmblood-fragile-foal-syndrome-wffs-qpcr","title":"FFS (WFFS) Fragile Foal Syndrome","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eWFFS DNA Test\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eEnsure the Health and Future of Your Horses with Accurate WFFS Testing.\u003c\/strong\u003e Our DNA test verifies the presence of the affected allele at the PLOD1 locus responsible for Warmblood Fragile Foal Syndrome (WFFS), also known as Fragile Foal Syndrome (FFS).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Requirements\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e30 to 40 hair roots - envelope\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test verifies the presence of the affected allele at the PLOD1 locus responsible for WFFS and presents results as one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present. The horse is not a carrier of the WFFS mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/WFFS:\u003c\/strong\u003e Carrier, heterozygous for WFFS. One mutated allele present. The horse can pass the WFFS allele to 50% of its progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS\/WFFS:\u003c\/strong\u003e Positive, homozygous for WFFS. Two mutated alleles present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eGenetic Inheritance\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eWarmblood Fragile Foal Syndrome (WFFS) is an inherited autosomal recessive disorder caused by a single mutation in the PLOD1 gene.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eClinical Signs and Affected Breeds\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe disease is present at birth. Affected foals have skin that lacks tensile strength, characterized by tearing, ulceration, and other lesions from normal contact. Lesions are most noted on pressure points, gums, and other oral cavity mucous membranes. Limb joints are lax and hyper-extensible, making it difficult for affected foals to stand normally.\u003c\/p\u003e\n\u003cp\u003eWFFS\/FFS is similar to Ehlers Danlos Syndrome (EDS) in humans. The mutation has been reported in Warmblood breeds (11-30% carriers) and at low frequency in Thoroughbreds (2.75% of Irish Thoroughbreds), as well as in Hanoverian, Selle Français, KWPN, Oldenburg, and Westphalians.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eTesting for WFFS is crucial for breeders to make informed decisions. By identifying carriers and avoiding breeding two carriers together, the risk of producing affected foals can be minimized. This helps ensure the health and wellbeing of future generations of horses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eDetailed Results Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present. The horse is not a carrier of the WFFS mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/WFFS:\u003c\/strong\u003e Carrier, heterozygous for WFFS. One mutated allele present. The horse can pass the WFFS allele to 50% of its progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS\/WFFS:\u003c\/strong\u003e Positive, homozygous for WFFS. Two mutated alleles present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eWarmblood Fragile Foal Syndrome (WFFS) is a fatal genetic defect of connective tissue, resulting from a mutation in the PLOD1 gene. WFFS is characterized by hyperextensible, fragile skin and mucous membranes, leading to severe lesions and often resulting in euthanasia of affected foals shortly after birth. This condition significantly impacts a horse's health and performance, making genetic testing an essential tool for breeders and buyers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAblondi, M., et al. (2022). \u003ca href=\"https:\/\/doi.org\/10.1186\/s12711-021-00693-4\" target=\"_blank\"\u003ePerformance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects\u003c\/a\u003e. Genet Sel Evol 54, 4.\u003c\/li\u003e\n\u003cli\u003eRowe, Á., et al. (2021). \u003ca href=\"https:\/\/doi.org\/10.1186\/s13620-021-00206-1\" target=\"_blank\"\u003eWarmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland\u003c\/a\u003e. Ir Vet J 74, 27.\u003c\/li\u003e\n\u003cli\u003eDias, N. M., et al. (2019). \u003ca href=\"https:\/\/doi.org\/10.1016\/j.tvjl.2019.05.002\" target=\"_blank\"\u003eWarmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil\u003c\/a\u003e. Vet J 248, 101–102.\u003c\/li\u003e\n\u003cli\u003eHoelzle, L., et al. (2020). \u003ca href=\"https:\/\/doi.org\/10.3390\/genes11121518\" target=\"_blank\"\u003eDistribution of the Warmblood Fragile Foal Syndrome Type 1 Mutation (PLOD1 c.2032G\u0026gt;A) in Different Horse Breeds from Europe and the United States\u003c\/a\u003e. Genes 11(12), 1518.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWFFS primarily affects Warmbloods but has also been detected in breeds like Thoroughbreds, Knabstruppers, Haflingers, and American Sport Ponies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is WFFS inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWFFS is inherited as an autosomal recessive trait, requiring two copies of the mutated gene (WFFS\/WFFS) for the disease to manifest. Affected foals with two copies of the WFFS mutation will not survive to adulthood and must be euthanized shortly after birth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can WFFS be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUnfortunately, there is no cure for WFFS. The condition is lethal, and affected foals exhibit severe clinical signs shortly after birth. The best management strategy is through genetic testing to inform breeding decisions and avoid producing affected foals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is it important to test for WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTesting for WFFS is crucial for breeders to make informed decisions. By identifying carriers and avoiding breeding two carriers together, the risk of producing affected foals can be minimized. This helps ensure the health and wellbeing of future generations of horses.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n        function toggleSection(id) {\n            var content = document.getElementById(id);\n            if (content.style.display === \"none\" || content.style.display === \"\") {\n                content.style.display = \"block\";\n            } else {\n                content.style.display = \"none\";\n            }\n        }\n    \u003c\/script\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435119468588,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/FFStest.png?v=1716900031"},{"product_id":"severe-combined-immunodeficiency-scid","title":"SCID Severe Combined Immunodeficiency","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eDNA test\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eDNA test for the Severe Combined Immunodeficiency (SCID). \u003c\/span\u003e\u003cspan class=\"s1\"\u003eSCID is an inherited disease seen in pure and part-bred Arab horses.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe DNA test for SCID helps breeders to identify the animals that are carriers of the SCID mutation. This information allows breeders to prevent two carriers from breeding, which reduce the chances of producing an SCID foal.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eContinued breeding of horses that are carriers of the SCID gene is now possible without the worry of producing SCID foals. For example, carrier stallions that possess highly desirable traits can now be selectively bred to clear (homozygous normal) mares (and vice versa). The resulting foals would have an equal chance of being a carrier or clear of SCID, but would definitely not be affected.\u003c\/li\u003e\n\u003cli\u003eThe foals could be tested anytime after birth to determine their SCID genotype and future matings could be rationally planned.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence recessive SCID mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan class=\"s1\"\u003enn \u003c\/span\u003e\u003c\/strong\u003e– \u003cstrong\u003eNon-carrier\u003c\/strong\u003e of the SCID gene.Tested negative for the SCID mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003enSCID \u003c\/strong\u003e– Heterozygous horse for SCID gene, both the normal and SCID alleles were detected. The horse is a carrier of SCID genetic disorder and there is a 50% chance this horse will pass a SCID allele to its offspring\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSCID SCID\u003c\/strong\u003e – Carrier of two copies of the SCID gene. Homozygous horse for SCID mutation. The horse is affected with the SCID genetic disorder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSevere Combined Immunodeficiency Disease (SCID) is an inherited disease seen in pure and part-bred Arab horses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAnimals with this inherited condition have an enhanced susceptibility to infection and first show signs of disease at between two days and eight weeks of age. Clinical diagnosis of the disease is not straightforward as the symptoms, such as raised temperature, respiratory complications and diarrhoea, are typical of new-born foals with a range of infections.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFoals affected by SCID always die from the disorder within the first six months of life. This happens regardless of the level of veterinary care. SCID is therefore a distressing condition for the effected animal and the owners or caregivers, and results in financial loss due to dead foals and veterinary expenses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe disorder is recessive, which means that a horse must be homozygous positive or have two copies of the defective gene to suffer from the disease. Consequently both the sire and the dam must possess at least one copy of the mutated gene in order for the offspring to be afflicted. Offspring born with one copy of the defective gene and one non-defective copy are considered a carrier and have a 50% chance of passing the defective gene on.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA number of studies have attempted to estimate the frequency of SCID carriers in the Arab horse population. Most sources speculate that the percentage of Arab foals which die of SCID is 2-3%.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIf breeding is random then it would imply that roughly 28-35% of Arab horses are carriers. However, most breeding is rather selective, making the true frequency of carriers in the population somewhat unclear.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451223236652,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/SCID.png?v=1571095001"},{"product_id":"hereditary-equine-regional-dermal-asthenia-herda","title":"HERDA Hereditary Equine Regional Dermal Asthenia","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for Hereditary Equine Regional Dermal Asthenia (HERDA). This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e test verifies the presence of the recessive HERDA gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis DNA test helps breeders to identify horses that carrying the HERDA recessive mutation. \u003c\/span\u003eInformed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive HERDA gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003cstrong\u003eNegative\u003c\/strong\u003e for HERDA. Absence of the defective gene responsible for HERDA.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/HERDA\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eCarrier - Positive heterozygous for HERDA\u003c\/strong\u003e. Presence of one copy of the allele responsible for HERDA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is a carrier for HERDA and can pass on a copy of HERDA allele to their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eHERDA\/ -\u003c\/strong\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003ePositive Homozygous for HERDA\u003c\/strong\u003e. Presence of two copies of the allele responsible for HERDA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected by\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eHERDA disorder and can pass the HERDA allele to 100% of their progeny when bred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHereditary equine regional dermal asthenia (HERDA) is a genetic skin disease predominantly found in the American Quarter Horse. Within the breed, the disease is prevalent in particular lines of cutting horses. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHERDA is characterised by hyper-extensible skin, scarring, and severe lesions along the back of affected horses. Affected foals rarely show symptoms at birth. The condition typically occurs by the age of two, most notably when the horse is first being broke to saddle. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThere is no cure, and the majority of diagnosed horses are euthanised because they are unable to be ridden and are inappropriate for future breeding. HERDA has an autosomal recessive mode of inheritance and affects stallions and mares in equal proportions.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451396677676,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HERDA.png?v=1571094928"},{"product_id":"glycogen-branching-enzyme-deficiency-gbed","title":"GBED Glycogen Branching Enzyme Deficiency","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Glycogen Branching Enzyme Deficiency (GBED). This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e DNA test verifies the presence of the\u003cstrong\u003e recessive GBED allele\u003c\/strong\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis DNA test identify \u003cstrong\u003einapparent carriers\u003c\/strong\u003e of the GBED fatal disorder. \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eIn \u003cstrong\u003ebreeding selection\u003c\/strong\u003e is recommended to avoid the crossbreeding of two GBED inapparent carriers to prevent\u003cem\u003e in utero\u003c\/em\u003e abortion of foetus and the birth of foals affected by GBED.\u003c\/span\u003e \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eTo confirm GBED in affected foals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDNA testing provide important tools for \u003cstrong\u003einformed choices\u003c\/strong\u003e about breeding selections to prevent abortion and the birth of affected foals.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e \u003cstrong\u003eFrequency and affected breeds\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMore frequent in Paint Horses and Quarter horses related breeds.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eA prevalence of  7,1% and 8,3% in the Paint and Quarter Horse breeds, respectively (Wagner et al., 2006).\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the\u003cstrong\u003e recessive GBED alleles\u003c\/strong\u003e and presents results as one of the following: \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003cstrong\u003eNegative\u003c\/strong\u003e for GBED. Absence of the defective allele responsible for GBED.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGBED\/N\u003c\/strong\u003e - \u003cstrong\u003eCarrier - Positive heterozygous for GBED\u003c\/strong\u003e. Presence of one copy of the allele responsible for GBED.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is a carrier for GBED and can pass on a copy of GBED allele to their progeny when bred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGBED\/ -\u003cspan class=\"Apple-converted-space\"\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003eAffected - Positive Homozygous for GBED\u003c\/strong\u003e. Presence of two copies of the allele responsible for GBED.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe animal is affected by GBED disorder. GBED is lethal causing abortion and\/or\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eneonatal mortality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGlycogen Branching Enzyme Deficiency (GBED) \u003cstrong\u003efatal condition\u003c\/strong\u003e caused by an \u003cstrong\u003eautosomal recessive\u003c\/strong\u003e genetic disorder that results in the bodies' inability to properly store sugar in the glycogen form.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eIn a \u003cstrong\u003enormal horse\u003c\/strong\u003e, the body stores sugar as energy by converting glucose to glycogen.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eThis \u003cstrong\u003egenetic disorder\u003c\/strong\u003e  affects the production of the enzyme needed to branch the glycogen structure, preventing the horse from being able to adequately store sugar in the glycogen form. This means that the horse will not be able to store enough energy to fuel important organs, such as the muscles and brain.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eUnfortunately, \u003cstrong\u003eGBED is always fatal. \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGBED often causes the foetus to be aborted \u003ci\u003ein utero. \u003c\/i\u003eWhen born \u003c\/span\u003e\u003cspan class=\"s1\"\u003emost affected foals will die in the first weeks of age\u003cstrong\u003e.\u003c\/strong\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eResearch studies showed that as many as 2,5% of aborted Quarter Horse foetus were homozygous for the GBED mutation \u003cspan\u003e(Wagner et al., 2006). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFoals born which are affected by GBED suffer from a range of clinical signs associated with this lack of sugar, such as low energy, weakness and difficulty rising.  \u003c\/span\u003e\u003cspan class=\"s1\"\u003eOther clinical signs include low body temperature, contracted muscles, seizures, and sudden death.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eREFERENCES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTryon RC, Penedo MC, McCue ME, Valberg SJ, Mickelson JR, Famula TR, Wagner ML, Jackson M, Hamilton MJ, Nooteboom S, Bannasch DL.\u003cstrong\u003e Evaluation of allele frequencies of inherited disease genes in subgroups of American Quarter Horses\u003c\/strong\u003e. J Am Vet Med Assoc. 2009 Jan 1;234(1):120-5. doi: 10.2460\/javma.234.1.120. PubMed PMID: 19119976.DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2460\/javma.234.1.120\" ref=\"aid_type=doi\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e10.2460\/javma.234.1.120\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eWagner ML, Valberg SJ, Ames EG, Bauer MM, Wiseman JA, Penedo MC, Kinde H, Abbitt B, Mickelson JR. \u003cstrong\u003eAllele frequency and likely impact of the glycogen branching enzyme deficiency gene in Quarter Horse and Paint Horse populations.\u003c\/strong\u003e J Vet Intern Med. 2006 Sep-Oct;20(5):1207-11. PubMed PMID: 17063718.DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1892\/0891-6640(2006)20%5B1207:afalio%5D2.0.co;2\" ref=\"aid_type=doi\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e10.1892\/0891-6640(2006)20[1207:afalio]2.0.co;2\u003c\/a\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451474927660,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/GBED.png?v=1571094714"},{"product_id":"advanced-profile-10-genetic-disorders","title":"DNA Disorder-Free Certified","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003cmeta name=\"description\" content=\"Ensure your horse's lineage is free from genetic disorders with our Certified DNA Disorder-Free Lines test. Certify your horse against 10 genetic disorders.\"\u003e \u003cmeta name=\"keywords\" content=\"DNA testing, horse genetics, genetic disorders, horse breeding, SCID, LFS, CA, PSSM1, HYPP, GBED, HERDA, MH, CM, WFFS\"\u003e \u003cmeta name=\"author\" content=\"Equigerminal\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eCertified DNA Disorder-Free Lines\u003c\/h2\u003e\n\u003cp class=\"highlight\"\u003eEnsure your horse's lineage is free from genetic disorders with our comprehensive DNA testing panel. Certify your horse against 10 genetic disorders: \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/severe-combined-immunodeficiency-scid\"\u003eSCID\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/lavander-foal-syndrome-lfs-qpcr\"\u003eLFS\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/cerebellar-abiotrophy\"\u003eCA\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/polyssaccharide-storage-myophaty-type-1-pssm1-qpcr\"\u003ePSSM1\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/hyperkalemic-periodic-paralysis-hypp\"\u003eHYPP\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/glycogen-branching-enzyme-deficiency-gbed\"\u003eGBED\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/hereditary-equine-regional-dermal-asthenia-herda\"\u003eHERDA\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/malignant-hyperthermia-mh\"\u003eMH\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/congenital-myotonia-cm\"\u003eCM\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/warmblood-fragile-foal-syndrome-wffs-qpcr\"\u003eWFFS\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eSample Collection\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Roots:\u003c\/strong\u003e 30 to 40 hair roots.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Sample:\u003c\/strong\u003e 5 mL blood in a K3 EDTA tube.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTurnaround Time\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 to 10 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Test?\u003c\/h2\u003e\n\u003cp\u003eOur Certified DNA Disorder-Free Lines test helps breeders, purchasers, and studbook certifiers ensure that horses are free from genetic disorders. This guarantees healthier horses, informed breeding decisions, and enhanced peace of mind.\u003c\/p\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch2\u003eResults Description\u003c\/h2\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/P1:\u003c\/strong\u003e Positive heterozygous. One mutated allele present. The horse can pass the allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP1\/P1:\u003c\/strong\u003e Positive homozygous. Two mutated alleles present. The horse will pass the allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAdditional Information\u003c\/h2\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease that affects many breeds. The condition is caused by a mutation in the GYS1 gene, leading to an abnormal accumulation of glycogen in the muscles. This can cause symptoms such as muscle tremors, stiffness, reluctance to move, and excessive sweating. Management of PSSM1 includes dietary changes and regular exercise to help mitigate symptoms.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is genetic testing important for horse breeders?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic testing is essential for breeders to make informed breeding decisions and to ensure that their horses do not carry alleles for genetic disorders. This helps in maintaining the health and performance of the breed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by SCID and LFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSCID and LFS are commonly found in Arabian horses and breeds influenced by Arabian bloodlines. Testing is crucial for breeding and purchasing decisions to ensure the health of the horses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow prevalent are genetic disorders in certain horse breeds?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic disorders can have significant frequencies in specific breeds. For example, HERDA is prevalent in Quarter Horses, while WFFS often affects Warmbloods. Regular testing helps in identifying carriers and making informed decisions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do genetic disorders impact horse health?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic disorders such as SCID, LFS, PSSM1, HYPP, and others can significantly impact the health, performance, and longevity of horses. Early detection through genetic testing allows for better management and breeding practices to ensure healthier future generations.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eHow it Works\u003c\/h2\u003e\n\u003cp\u003e✨ \u003cstrong\u003ePurchase the Test:\u003c\/strong\u003e Select and buy the DNA test online.\u003c\/p\u003e\n\u003cp\u003e📄 \u003cstrong\u003eReceive Instructions:\u003c\/strong\u003e After payment confirmation, receive instructions for hair root collection and a printable submission form.\u003c\/p\u003e\n\u003cp\u003e✂️ \u003cstrong\u003eCollect Hair Roots:\u003c\/strong\u003e Pluck hair roots, tape them on the submission form, place it in an envelope or sealed plastic bag.\u003c\/p\u003e\n\u003cp\u003e📬 \u003cstrong\u003eSend Samples:\u003c\/strong\u003e Send to our lab by regular mail or express delivery to:\u003c\/p\u003e\n\u003cp\u003eEquigerminal Lab\u003cbr\u003eRua Eduardo Correia, Nº13\u003cbr\u003e3030-504 Coimbra, PORTUGAL\u003c\/p\u003e\n\u003cp\u003e📧 \u003cstrong\u003eReceive Results:\u003c\/strong\u003e Get the result certificate by email. If you need assistance, contact us at support@equigerminal.pt.\u003c\/p\u003e\n\u003cp\u003e♻️ \u003cstrong\u003eNote:\u003c\/strong\u003e No need for a sample collection kit, enhancing sustainability by reducing waste and plastic use.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990970179734,"sku":"","price":299.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/CertifiedDNADisorder-FreeLines.png?v=1721076875"},{"product_id":"lcorl-projected-height-test","title":"Projected Height test, LCORL\/NCAPG","description":"\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test kit\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test to predict the genetic potential for being a \u003cstrong\u003esmall\u003c\/strong\u003e, \u003cstrong\u003emedium\u003c\/strong\u003e or \u003cstrong\u003etall\u003c\/strong\u003e height horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood  - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 to 8  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e \u003cspan class=\"s1\"\u003eConfidently predict the expected mature height at withers of a young foal.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eIdentify horses that are 70% likely to be within the specific height range desired by the owner.\u003c\/li\u003e\n\u003cli\u003eProduce horses of a desired height more consistently.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the (C) allele associated to tall height horses, and presents the results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e \u003cstrong\u003eC\/C\u003c\/strong\u003e – \u003cstrong\u003eTall physical height\u003c\/strong\u003e. This genotype, with two copies of the (C) allele,\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eis associated with large horses, (169+\/-4 cm height at the withers). This genotype can be found in draught horses, Westphalians (31%), Oldenburgs (29%), Hanoverians (28%), Holsteiners (18%) and Pureblood Lusitanos (4%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT\/C\u003c\/strong\u003e – \u003cstrong\u003eMedium physical height\u003c\/strong\u003e. This genotype, with one copy of the (T) allele and another of the (C) allele,\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eis associated with medium-sized horses (164+\/-5 cm height at the withers). This genotype can be found in the Holsteiner (64%), Westphalian (60%), Hanoverian (56%) and Pureblood Lusitano (29%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT\/T\u003c\/strong\u003e – \u003cstrong\u003eSmall physical height\u003c\/strong\u003e. This genotype, with two copies of the (T) allele, is associated with smaller horses (159 +\/- 4 cm height at the withers) and ponies (\u0026lt;148 cm height at the withers). This genotype can be found in the majority of ponies, Arabs (100%) and Pureblood Lusitanos (67%). \u003cspan class=\"Apple-converted-space\"\u003e                               \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/PHtest_1024x1024.png?v=1573246253\" style=\"float: none;\" width=\"1024x1024\" height=\"1024x1024\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe development of the skeletal apparatus is regulated by the expression of the gene LCORL.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eRecent studies have identified a variation of a simple nucleotide base (Single Nucleotide Polymorphism) in the promoter of this gene.\u003c\/li\u003e\n\u003cli\u003eThe replacement of a thymine (T) with a cytosine (C) varies the expression of the LCORL gene. This variation in the expression influences the horse’s dimension. Consequently, if the expression of the LCORL gene is diminished the resulting horse has a larger body dimension (bones are longer).\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":30303074287660,"sku":"","price":62.73,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Cx_Projected_Height.png?v=1580503071"},{"product_id":"equine-herpesvirus-type-1-equine-herpesvirus-type-4-qpcr","title":"Equine Herpesvirus Type 1 \u0026 Equine Herpesvirus Type 4, qPCR","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp class=\"p1\" data-mce-fragment=\"1\"\u003e\u003cspan class=\"s1\" data-mce-fragment=\"1\"\u003e\u003cstrong\u003eTwo qPCR test, \u003c\/strong\u003eone\u003cstrong\u003e \u003c\/strong\u003ethat \u003c\/span\u003e\u003cspan class=\"s1\" data-mce-fragment=\"1\"\u003edetects the\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eof  Equine Herpesvirus Type 1 (\u003cstrong\u003eEHV-1\u003c\/strong\u003e) and one that detects the genome (DNA) of Equine Herpesvirus Type 4 (\u003cstrong\u003eEHV-4\u003c\/strong\u003e).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli\u003e\n\u003cstrong\u003e1 nasal or nasopharyngeal swab\u003c\/strong\u003e ( see\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\" aria-describedby=\"a11y-external-message\" data-mce-href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EHV1_4_AAEP.pdf?v=1614720976\"\u003e AAEP guidelines)\u003c\/a\u003e \u003c\/li\u003e\n\u003cli\u003eand\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e5 mL - K3 EDTA tube\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e2 to 5 working days\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e24-48h - please contact lab\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/inside.fei.org\/fei\/your-role\/veterinarians\/biosecurity-movements\/biosecurity\/testing-labs\"\u003e Our lab is approved by FEI for EHV-1 testing.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/inside.fei.org\/fei\/your-role\/veterinarians\/biosecurity-movements\/biosecurity\/testing-labs\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/1200px-FEI_Logo_RGB_Purple.svg_a1c2e1cd-e453-4940-bdd8-69689978c01f_480x480.png?v=1645556618\" width=\"103\" height=\"55\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 1?\u003c\/strong\u003e\u003c\/span\u003e more info \u003ca href=\"https:\/\/equigerminal.shop\/products\/equine-herpesvirus-type-1-1pcr?_pos=4\u0026amp;_sid=ea0a61397\u0026amp;_ss=r\"\u003ehere\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 4? \u003c\/strong\u003e\u003c\/span\u003emore info \u003ca href=\"https:\/\/equigerminal.shop\/products\/equine-herpesvirus-type-4-qpcr?_pos=2\u0026amp;_sid=78f228717\u0026amp;_ss=r\"\u003ehere\u003c\/a\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":39302962315414,"sku":"","price":86.1,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/EHV1_4.png?v=1614718197"},{"product_id":"equine-uterine-culture","title":"Equine uterine culture","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eParameter\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\u003cspan\u003eCulture of the uterus \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eUterine swab in \u003cspan data-mce-fragment=\"1\"\u003especial culture transport system\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eTurnaround time\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e1-15 day for bacterial growth\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\u003cspan\u003eSeveral days (\u0026gt;15) for yeast and other fungal growth \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":40176243245206,"sku":"","price":39.43,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Equineuterineculture.png?v=1625047395"},{"product_id":"special-offer-package-pssm1-wffs-30-off","title":"WFFS\/FFS \u0026 PSSM1 - DNA Test bundle","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eDNA Test Bundle: PSSM1 \u0026amp; WFFS\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eDiscover Peace of Mind with Precision Equine Genetics.\u003c\/strong\u003e Our DNA test bundle offers a comprehensive genetic screening for Polysaccharide Storage Myopathy Type 1 (PSSM1) and Warmblood Fragile Foal Syndrome (WFFS), empowering you with essential information for the wellbeing of your equine companion.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTests Included\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 Genetic Test:\u003c\/strong\u003e Uncover the presence of the specific allele at the GYS1 locus responsible for PSSM1, a condition affecting muscle metabolism in horses. Early detection can guide management and care. Learn more about the PSSM1 test \u003ca href=\"https:\/\/equigerminal.shop\/products\/polyssaccharide-storage-myophaty-type-1-pssm1-qpcr\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS Genetic Test:\u003c\/strong\u003e This test identifies the allele at the PLOD1 locus responsible for Warmblood Fragile Foal Syndrome (WFFS). Knowing your horse's genetic status aids in making informed breeding decisions. Further details on the WFFS test can be found \u003ca href=\"https:\/\/equigerminal.shop\/products\/warmblood-fragile-foal-syndrome-wffs-qpcr?_pos=2\u0026amp;_sid=1c7559dd5\u0026amp;_ss=r\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Collection\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e20-30 hair roots. Tape the hair to the\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\"\u003e printable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood in an EDTA tube. Send the tube with the \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" target=\"_blank\" rel=\"noopener\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremium Processing:\u003c\/strong\u003e Results in 2 working days after sample arrival. \u003cmeta charset=\"UTF-8\"\u003e \u003cspan\u003eThis service includes free express delivery. For an additional fee of €35, the laboratory arranges express shipping with package pick-up from your address (available for non-remote regions). For premium processing, please contact the laboratory at \u003c\/span\u003e\u003ca rel=\"noreferrer\" target=\"_new\"\u003esupport@equigerminal.pt\u003c\/a\u003e\u003cspan\u003e for further assistance.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cp\u003eThis genetic test helps breeders identify horses carrying the PSSM1 and WFFS alleles. Informed breeding choices can prevent the birth of affected foals. While PSSM1 affects muscle metabolism, WFFS is a fatal connective tissue disorder. Testing for these conditions is often required by studbooks and is highly recommended during pre-purchase exams to ensure the horse's health and performance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/n:\u003c\/strong\u003e Negative for PSSM1. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/P1:\u003c\/strong\u003e Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 P1\/P1:\u003c\/strong\u003e Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/WFFS:\u003c\/strong\u003e Carrier for WFFS. One copy of the mutated allele present. The horse can pass the WFFS allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS WFFS\/WFFS:\u003c\/strong\u003e Positive for WFFS. Two copies of the mutated allele present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease. Such foals will not survive to adulthood and hence will not pass on the allele.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease affecting many breeds, caused by a mutation in the GYS1 gene. Warmblood Fragile Foal Syndrome (WFFS) is a fatal genetic defect of connective tissue, resulting from a mutation in the PLOD1 gene. WFFS is characterized by hyperextensible, fragile skin and mucous membranes, leading to severe lesions and often resulting in euthanasia of affected foals shortly after birth. Both conditions can significantly impact a horse's health and performance, making genetic testing an essential tool for breeders and buyers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\nAblondi, M., et al. (2022). \u003ca href=\"https:\/\/doi.org\/10.1186\/s12711-021-00693-4\" target=\"_blank\"\u003ePerformance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects\u003c\/a\u003e. Genet Sel Evol 54, 4.Rowe, Á., et al. (2021). \u003ca href=\"https:\/\/doi.org\/10.1186\/s13620-021-00206-1\" target=\"_blank\"\u003eWarmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland\u003c\/a\u003e. Ir Vet J 74, 27.Dias, N. M., et al. (2019). \u003ca\u003eDias, N. M., et al. (2019). \u003c\/a\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.tvjl.2019.05.002\" target=\"_blank\"\u003eWarmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil\u003c\/a\u003e. Vet J 248, 101–102.Hoelzle, L., et al. (2020). \u003ca href=\"https:\/\/doi.org\/10.3390\/genes11121518\" target=\"_blank\"\u003eDistribution of the Warmblood Fragile Foal Syndrome Type 1 Mutation (PLOD1 c.2032G\u0026gt;A) in Different Horse Breeds from Europe and the United States\u003c\/a\u003e. Genes 11(12), 1518.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\u003c\/p\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by PSSM1 and WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. WFFS primarily affects Warmbloods but has also been detected in breeds like Thoroughbreds, Knabstruppers, Haflingers, and American Sport Ponies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow are PSSM1 and WFFS inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 is inherited in an autosomal dominant manner, meaning horses with one (n\/P1) or two (P1\/P1) copies of the mutated gene can develop the disease. WFFS is inherited as an autosomal recessive trait, requiring two copies of the mutated gene (WFFS\/WFFS) for the disease to manifest. Affected foals with two copies of the WFFS mutation will not survive to adulthood and must be euthanized shortly after birth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can PSSM1 and WFFS be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 management includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. WFFS, however, is a lethal condition with no cure, emphasizing the importance of genetic testing to inform breeding decisions and avoid producing affected foals.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990960906390,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/FFSPSSM1.png?v=1711469296"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/collections\/Discover_your_animal_heart_health_30.png?v=1782467039","url":"https:\/\/www.equigerminal.org\/en-it\/collections\/breeding-reproduction.oembed","provider":"Equigerminal","version":"1.0","type":"link"}