{"product_id":"equine-herpesvirus-qpcr","title":"Equine Herpesvirus Type 2, qPCR","description":"\u003cp\u003e\u003cspan style=\"color: #c729d2;\"\u003e\u003cstrong\u003ePathogen test \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe\u003cstrong\u003e\u003cspan\u003e q\u003c\/span\u003ePCR test\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003e detects the\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003e\u003cstrong\u003egenome (DNA)\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eof  Equine Herpesvirus Type 2 (EHV-2).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003e Serological detection of EHV-2 is of limited use to determine the re-activation of this herpesvirus. EHV-2 can remain latent in affected animals while shedding at levels adequate to infect other horses.\u003cstrong\u003e Molecular detection\u003c\/strong\u003e of EHV-2 by qPCR is the most sensitive, specific and accurate tool in assessing the infectivity of an affected horse.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c729d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e1 nasopharyngeal swab - dry swab\u003c\/li\u003e\n\u003cli\u003e5 mL - K3 EDTA tube\u003c\/li\u003e\n\u003cli\u003e5 mL - liquor (CSF) - sterile tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c729d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhat is Herpesvirus Type 2?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquine Herpesvirus Type1 2 (EHV-2) was recently classified within the Gammaherpesvirinae subfamily. EHV-2 is widely spread in horse populations and it has been isolated from healthy animals as well as from horses with different clinical signs.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e EHV-2 is able to establish persistent infections. Various observations indicate that EHV-2 should not be neglected as a pathogen in equids. There are convincing results indicating that EHV-2 has a role as a predisposing factor for \u003cem\u003eRhodococcus equ\u003c\/em\u003ei invasion in the respiratory tract. Also as been suggested that EHV-2 may play a role in transactivation and reactivation of latent EHV-1 and EHV-4 infections.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eClinical signs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEHV-2 infection occurs most frequently in young foals, and the most common symptoms are keratoconjunctivitis, respiratory disease with pneumonia and pharyngitis, fever, enlarged lymph nodes, inappetence\/anorexia, general malaise, and poor performance.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThere is no evidence that EHV-2 has abortigenic potential.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eTransmission\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe prowess of EHV-2 as a successfully adapted viral parasite of the horse is substantiated by seroepidemiological and virological studies which indicate almost universal acquisition of viral infection by young foals.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe limited data collected supports the scenario that EHV-2, in aerosolised infective material excreted from the respiratory tract of another virus-shedding horse, enters the new host through the upper respiratory tract where it infects and replicates first in the respiratory mucosal epithelium.\u003c\/li\u003e\n\u003cli\u003ePrenatal infection with EHV-2 has not been recorded, and the virus has not been detected in colostrum or milk.\u003c\/li\u003e\n\u003cli\u003eExperimental infection of a mid-gestational equine foetus in utero resulted in normal term delivery, although the foal showed mild rhinitis and conjunctivitis, with nasal shed- ding of EHV-2.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003ePrevention\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eOn the basis of evidence suggesting that EHV-2 infection can play an etiological role in predisposing foals to subsequent \u003cem\u003eR. equi\u003c\/em\u003e pneumonia, both passive immunisation with hyperimmune equine serum against EHV-2 and active immunisation with an vaccine containing EHV-2 glycoprotein antigens have been used, with reported success, for the prophylactic treatment of annual reoccurrences of this highly fatal foal disease.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eOcular disease in foals associated with infection by EHV-2 on breeding farms has been successfully treated with ophthalmic ointments containing either idoxuridine or trifluridine together with antibiotics and non-steroidal anti-inflammatory agents.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29396176928812,"sku":"","price":55.35,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HEV-2.png?v=1571168299","url":"https:\/\/www.equigerminal.org\/eu\/products\/equine-herpesvirus-qpcr","provider":"Equigerminal","version":"1.0","type":"link"}