{"product_id":"malignant-hyperthermia-mh","title":"MH Malignant hyperthermia","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Malignant hyperthermia (MH). This\u003c\/span\u003e test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\"\u003eTurnaround time\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eNegative for MH\u003c\/strong\u003e.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eAbsence of the allele responsible for Malignant Hyperthermia (MH).\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/N\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive heterozygous for MH\u003c\/strong\u003e. Presence of one copy of the allele responsible for MH. The horse is affected with the MH disorder and can pass the MH allele\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eto 50% of their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/\u003c\/strong\u003e -\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive homozygous for MH\u003c\/strong\u003e. Presence of two copies of the allele responsible for MH.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected with the MH disorder and will pass the MH allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMalignant Hyperthermia or MH is a genetic muscle disorder that affects Quarter Horses and related breeds. Horses with the MH mutation may not show any physical signs of the disorder until triggered by exposure to anaesthesia or extreme exercise or stress. Symptoms can include high temperature, increased heart rate, high blood pressure, sweating, acidosis, and muscle rigidity. Symptoms develop rapidly, and if not treated quickly, this condition can be fatal. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMH is inherited as an autosomal dominant trait, so the disorder can be passed on even if only one parent has the defective gene. The mutation can be present along with PSSM and if a horse also has PSSM, the symptoms associated with MH can be more severe. Therefore, testing for both PSSM and MH is recommended for Quarter Horse breeds.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAlthough this condition is rare, testing for MH is recommended in case a horse must undergo anaesthesia. Horses that are known to have the MH mutation can be given medication prior to administering anaesthesia to help reduce the severity of the symptoms.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451615731756,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Hyperthermia_maligna.png?v=1571094693","url":"https:\/\/www.equigerminal.org\/eu\/products\/malignant-hyperthermia-mh","provider":"Equigerminal","version":"1.0","type":"link"}