{"product_id":"melanoma-dermal-melanoma","title":"Melanoma","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e2 DNA tests that can help to predict the possible type of incidence for developing  dermal melanomas on grey horses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis 2 DNA tests for melanoma confirms if the grey horse is heterozygous (G\/N) or homozygous (G\/) for the Grey gene and if is Homozygous for non-agouti (a\/a).\u003c\/span\u003eThe results can predict the type incidence for developing dermal melanomas.  \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe genetic profile test verifies the genotype of the Grey and Agouti genes, and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003cspan class=\"s1\"\u003eMelanoma incidence risk\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cstrong\u003eG\/N\u003c\/strong\u003e + \u003c\/span\u003e\u003cstrong\u003eA\/a\u003c\/strong\u003e or \u003cstrong\u003eA\/A\u003c\/strong\u003e – \u003cstrong\u003eModerate incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/N\u003c\/strong\u003e + \u003cstrong\u003ea\/a\u003c\/strong\u003e – \u003cstrong\u003eModerate to high incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/G\u003c\/strong\u003e + \u003cstrong\u003eA\/a\u003c\/strong\u003e or \u003cstrong\u003eA\/A\u003c\/strong\u003e – \u003cstrong\u003eHigh incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/G\u003c\/strong\u003e + \u003cstrong\u003ea\/a\u003c\/strong\u003e – \u003cstrong\u003eVery high incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMost melanomas found in horses are benign.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eOnce present these benign types of melanoma are not aggressive in their growth and may progress over several years requiring little treatment. A melanoma is one of the most common skin tumors seen in a horse or pony.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey horses have a high incidence of dermal melanomas that are commonly seen around the tail and head. Over 80% of Grey horses older than 15 years will develop melanoma.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey homozygotes are more likely to develop melanoma than heterozygotes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey horses that are homozygous for non-agouti (aa) genotype at the Agouti locus, also have a higher risk for melanoma. Many Grey horses show depigmentation of the skin around the eyes, mouth and anus but there are no health risks associated with this condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMalignant melanomas in horses can cause severe problems and can be life-threatening. Problems develop when melanomas are present internally or if they become so large that they ulcerate, bleed and become infected.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eEquine melanomas sometimes grow so large that they can cause severe weight loss and\/or colic. If a melanoma is situated on the head in an area where a bridle, saddle, head collar or rug might rub, it will be uncomfortable for the horse, potentially causing behavioural problems. Infections can also occur.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451118936108,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Melanoma.png?v=1571095012","url":"https:\/\/www.equigerminal.org\/eu\/products\/melanoma-dermal-melanoma","provider":"Equigerminal","version":"1.0","type":"link"}