{"title":"Genetic Testing","description":"\u003cdiv style=\"color: #333; font-family: Arial, sans-serif;\" class=\"product-description\"\u003e\n\u003ch3 style=\"color: #2e6da4;\"\u003e\u003cstrong\u003eDiscover Your Horse's Genetics: Simple, Non-Invasive DNA Testing\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAnimal-friendly 🐾 and eco-conscious 🌿.\u003c\/p\u003e\n\u003cp\u003eGet to know your horse's genetic profile with our DNA testing services - as easy as combing their hair. Our non-invasive testing options are designed to be gentle and stress-free for your horse, eliminating the need for blood or needles.\u003c\/p\u003e\n\u003cp\u003eExplore our range of genetic tests for \u003cstrong\u003edisorders\u003c\/strong\u003e, \u003cstrong\u003etraits\u003c\/strong\u003e, \u003cstrong\u003ecoat color and pattern\u003c\/strong\u003e, \u003cstrong\u003eparentage testing\u003c\/strong\u003e, and more.\u003c\/p\u003e\n\u003ch3 style=\"color: #2e6da4;\"\u003eEco-friendly ♻️\u003c\/h3\u003e\n\u003cp\u003eSay goodbye to traditional sample collection kits and embrace sustainability with reduced waste and minimal plastic use. Order now and receive a printable sample submission form for DNA testing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWe offer PREMIUM processing services for urgent results in just 1-2 days.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca style=\"color: #00afab; text-decoration: none; font-weight: bold;\" href=\"https:\/\/equigerminal.shop\/pages\/how-it-works\"\u003eFind out how it works\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" title=\"DNA testing - sample submission form\"\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cspan\u003e\u003cb\u003eDNA testing printable sample submission form\u003c\/b\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e","products":[{"product_id":"lethal-white-foal-syndrome-lwfs-qpcr","title":"LWFS Lethal White Foal Syndrome","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Overo gene that is associated with the Lethal White Foal Syndrome (LWFS).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\nor\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe relationship between Lethal White Foal Syndrome (LWFS) and the frame overo coat pattern is not always straightforward. Usually carriers of LWFS are frame overo in pattern, and have 1 copy of the mutated allele (nL). But not all frame overo horses carry the mutated allele, some have the genotype (nn).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eAnd some horses with other coat patterns (including solid coloured paints and tobiano) have been found to carry the mutated allele.\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIt should also be remembered that not all white foals have the genotype (LL) ,and may not be affected by LWFS.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the mutation associated to the Overo and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e \u003cb\u003eN\/\u003c\/b\u003e\u003c\/span\u003e – \u003cstrong\u003eNon-Overo\u003c\/strong\u003e or ‘solid’ horse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eO\/N\u003c\/b\u003e – \u003cstrong\u003eFrame Overo\u003c\/strong\u003e horse. Horse carries just a single copy of frame Overo. Since frame Overo is a dominant gene, the coat pattern should be present in all horses with a single copy of the mutated gene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eO\/\u003c\/strong\u003e – A \u003cstrong\u003eLethal White Foal Syndrome\u003c\/strong\u003e (LWFS). Foal carries two copies, homozygous for frame Overo. Since no living frame Overo horse more than a week old will test as being homozygous, it applies only to horses in the Lethal White condition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo is a highly desirable white pattern gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll Frame Overo horses carry a single inherited copy of the Ile118Lys EDNRB mutation. This mutation causes pigment loss, producing white markings on certain areas of the horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eWhile the mutation produces visually desirable horses, it is also linked to a fatal condition known as Lethal White Foal Syndrome (LWFS), whereby a foal is born almost pure white in appearance, and dies within its first few days of life. Correct breeding can avoid this occurrence.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003cspan class=\"s1\"\u003eLWFS occurs when a horse inherits two copies of the mutated gene, one from both parents. Whereas horses with just one copy of the gene will live normally and exhibit the desirable pattern. A horse with two copies of the mutated gene will suffer intestinal abnormalities caused by undeveloped nerves of the foal’s digestive system. These animals die within the first 72 hours of being born and are typically euthanized sooner for humane reasons.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo horses which carry just a single copy of the gene, will pass one copy of it to their foals approximately 50% of the time when bred.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTherefore, when breeding an Overo horse to a solid non-Overo horse, the foal can only inherit one copy. However, if two Overo horses are bred together they could potentially both pass the Overo gene to the foal, meaning it inherits two copies. Horses which inherit two copies of Frame Overo will suffer the Lethal White condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eProper mating must be carried out to ensure that two frame Overo horses do not breed. This will prevent any risk of the foal inheriting two copies of the mutated gene.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435113340972,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/LethalWhiteFoalSyndrome.png?v=1662540405"},{"product_id":"lavander-foal-syndrome-lfs-qpcr","title":"LFS Lavender Foal Syndrome","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Lavender Foal Syndrome (LFS) – Pure and part-bred Arab horses. This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e test verifies the presence of the recessive LFS gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis genetic test determines LFS clear, carrier or affected status. Informed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive LFS gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e N\/\u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003c\/strong\u003e–\u003cstrong\u003e Non-carrier\u003c\/strong\u003e of the LFS gene. Tested negative for the LFS gene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/LFS\u003c\/strong\u003e - \u003cstrong\u003eHeterozygous\u003c\/strong\u003e horse for LFS, both the normal and LFS alleles were detected. The horse is a carrier of LFS genetic disorder and there is a 50% chance this horse will pass a LFS allele to its offspring\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLFS\/\u003c\/strong\u003e – \u003cstrong\u003eHomozygous\u003c\/strong\u003e horse for LFS, carrier of two copies of the LFS gene. The horse is affected with the LFS genetic disorder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eLavender Foal Syndrome (LFS) is a recessive genetic disorder.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAffected foals born with the unique diluted coat color that can appear to be pale lavender, pale pink or silver. This foals-often have a difficult delivery, problems standing at birth and usually have episodes where they rigidly extend their limbs, neck and back. These episodes tend to resemble a seizure, although the affected foal does not seem normal between episodes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll affected foals are usually euthanised within days or weeks of birth.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eLFS is rare and is considered to be an autosomal recessive trait. “Autosomal” means that there is no sex linkage, so both males and females can be equally affected. “Recessive” means that in order for a foal to be affected, it must have received two copies of the mutated gene, inheriting one copy from each parent.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses that have one copy of the mutated gene, in combination with one copy of the normal gene, are physically normal but are considered carriers and have a 50% probability, each time they are bred, of passing the mutation along to their offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe SNP mutation that causes LFS has not been detected in other breeds.\u003c\/span\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTesting for this mutation in horses with no Arabian blood lines is not recommended. However, in cases where pedigree is not known, testing could be a useful tool to prevent possible affected foals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435115274284,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Lavander_Foal.png?v=1571095199"},{"product_id":"polyssaccharide-storage-myophaty-type-1-pssm1-qpcr","title":"PSSM1 Polysaccharide Storage Myopathy Type 1","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eAbout the Test\u003c\/h2\u003e\n\u003cp class=\"highlight\"\u003eThe PSSM1 DNA test verifies the presence of the affected allele at the GYS1 locus responsible for Polysaccharide Storage Myopathy Type 1 (PSSM1).\u003c\/p\u003e\n\u003ch2\u003eSample Collection\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Roots:\u003c\/strong\u003e 20 to 30 hair roots. Pull the hair and tape it onto the \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Sample:\u003c\/strong\u003e 5 mL blood in a K3 EDTA tube. Collect the blood and send the tube together with the \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" target=\"_blank\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTurnaround Time\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Test?\u003c\/h2\u003e\n\u003cp\u003eThis genetic test helps breeders identify horses carrying the PSSM allele. Informed breeding choices can prevent the birth of affected foals. While PSSM cannot be cured, muscle function can be managed with dietary changes and exercise routines.\u003c\/p\u003e\n\u003cp\u003eThe PSSM1 test is required by many studbooks and is highly recommended when considering the purchase of a horse. Testing for PSSM1 as part of the pre-purchase examination can ensure that you are making an informed decision, as the condition can impact the horse's performance and overall health.\u003c\/p\u003e\n\u003ca class=\"toggle-btn\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch2\u003eResults Description\u003c\/h2\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for PSSM1. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/P1:\u003c\/strong\u003e Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP1\/P1:\u003c\/strong\u003e Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAdditional Information\u003c\/h2\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease that affects many breeds. The condition is caused by a mutation in the GYS1 gene, leading to an abnormal accumulation of glycogen in the muscles. This can cause symptoms such as muscle tremors, stiffness, reluctance to move, and excessive sweating. Management of PSSM1 includes dietary changes and regular exercise to help mitigate symptoms.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by PSSM1?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. The prevalence of the mutation varies by breed, with some breeds having a higher incidence of the condition.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is PSSM1 inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 is inherited in an autosomal dominant manner, meaning that horses with one (n\/P1) or two (P1\/P1) copies of the mutated gene can develop the disease. Horses with two copies generally show more severe symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can PSSM1 be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eManagement includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. These measures can help prevent the onset of symptoms or reduce their severity.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Standard. Results in 5 days","offer_id":47813083988296,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/PSSM1test.png?v=1716890764"},{"product_id":"warmblood-fragile-foal-syndrome-wffs-qpcr","title":"FFS (WFFS) Fragile Foal Syndrome","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eWFFS DNA Test\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eEnsure the Health and Future of Your Horses with Accurate WFFS Testing.\u003c\/strong\u003e Our DNA test verifies the presence of the affected allele at the PLOD1 locus responsible for Warmblood Fragile Foal Syndrome (WFFS), also known as Fragile Foal Syndrome (FFS).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Requirements\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e30 to 40 hair roots - envelope\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test verifies the presence of the affected allele at the PLOD1 locus responsible for WFFS and presents results as one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present. The horse is not a carrier of the WFFS mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/WFFS:\u003c\/strong\u003e Carrier, heterozygous for WFFS. One mutated allele present. The horse can pass the WFFS allele to 50% of its progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS\/WFFS:\u003c\/strong\u003e Positive, homozygous for WFFS. Two mutated alleles present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eGenetic Inheritance\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eWarmblood Fragile Foal Syndrome (WFFS) is an inherited autosomal recessive disorder caused by a single mutation in the PLOD1 gene.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eClinical Signs and Affected Breeds\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe disease is present at birth. Affected foals have skin that lacks tensile strength, characterized by tearing, ulceration, and other lesions from normal contact. Lesions are most noted on pressure points, gums, and other oral cavity mucous membranes. Limb joints are lax and hyper-extensible, making it difficult for affected foals to stand normally.\u003c\/p\u003e\n\u003cp\u003eWFFS\/FFS is similar to Ehlers Danlos Syndrome (EDS) in humans. The mutation has been reported in Warmblood breeds (11-30% carriers) and at low frequency in Thoroughbreds (2.75% of Irish Thoroughbreds), as well as in Hanoverian, Selle Français, KWPN, Oldenburg, and Westphalians.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eTesting for WFFS is crucial for breeders to make informed decisions. By identifying carriers and avoiding breeding two carriers together, the risk of producing affected foals can be minimized. This helps ensure the health and wellbeing of future generations of horses.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eDetailed Results Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present. The horse is not a carrier of the WFFS mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/WFFS:\u003c\/strong\u003e Carrier, heterozygous for WFFS. One mutated allele present. The horse can pass the WFFS allele to 50% of its progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS\/WFFS:\u003c\/strong\u003e Positive, homozygous for WFFS. Two mutated alleles present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eWarmblood Fragile Foal Syndrome (WFFS) is a fatal genetic defect of connective tissue, resulting from a mutation in the PLOD1 gene. WFFS is characterized by hyperextensible, fragile skin and mucous membranes, leading to severe lesions and often resulting in euthanasia of affected foals shortly after birth. This condition significantly impacts a horse's health and performance, making genetic testing an essential tool for breeders and buyers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAblondi, M., et al. (2022). \u003ca href=\"https:\/\/doi.org\/10.1186\/s12711-021-00693-4\" target=\"_blank\"\u003ePerformance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects\u003c\/a\u003e. Genet Sel Evol 54, 4.\u003c\/li\u003e\n\u003cli\u003eRowe, Á., et al. (2021). \u003ca href=\"https:\/\/doi.org\/10.1186\/s13620-021-00206-1\" target=\"_blank\"\u003eWarmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland\u003c\/a\u003e. Ir Vet J 74, 27.\u003c\/li\u003e\n\u003cli\u003eDias, N. M., et al. (2019). \u003ca href=\"https:\/\/doi.org\/10.1016\/j.tvjl.2019.05.002\" target=\"_blank\"\u003eWarmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil\u003c\/a\u003e. Vet J 248, 101–102.\u003c\/li\u003e\n\u003cli\u003eHoelzle, L., et al. (2020). \u003ca href=\"https:\/\/doi.org\/10.3390\/genes11121518\" target=\"_blank\"\u003eDistribution of the Warmblood Fragile Foal Syndrome Type 1 Mutation (PLOD1 c.2032G\u0026gt;A) in Different Horse Breeds from Europe and the United States\u003c\/a\u003e. Genes 11(12), 1518.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWFFS primarily affects Warmbloods but has also been detected in breeds like Thoroughbreds, Knabstruppers, Haflingers, and American Sport Ponies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is WFFS inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWFFS is inherited as an autosomal recessive trait, requiring two copies of the mutated gene (WFFS\/WFFS) for the disease to manifest. Affected foals with two copies of the WFFS mutation will not survive to adulthood and must be euthanized shortly after birth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can WFFS be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUnfortunately, there is no cure for WFFS. The condition is lethal, and affected foals exhibit severe clinical signs shortly after birth. The best management strategy is through genetic testing to inform breeding decisions and avoid producing affected foals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is it important to test for WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTesting for WFFS is crucial for breeders to make informed decisions. By identifying carriers and avoiding breeding two carriers together, the risk of producing affected foals can be minimized. This helps ensure the health and wellbeing of future generations of horses.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n        function toggleSection(id) {\n            var content = document.getElementById(id);\n            if (content.style.display === \"none\" || content.style.display === \"\") {\n                content.style.display = \"block\";\n            } else {\n                content.style.display = \"none\";\n            }\n        }\n    \u003c\/script\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29435119468588,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/FFStest.png?v=1716900031"},{"product_id":"extension-base-colour","title":"Extension, Chestnut or Sorrel","description":"\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\"\u003e DNA test\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Extension gene that controls the production of black or red pigment throughout the coat.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe DNA testing for the Extension gene can be used to identify those black horses for which neither pedigree nor breeding records is informative for identifying carriers of the recessive red factor.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eSince red is inherited as a recessive trait, it is relatively easy to start up a breeding program that will produce only red horses. It has been more difficult to initiate a black breeding program as black (Ee) horses can produce red foals. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test for Extension gene verifies the base coat color and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eE\/E\u003c\/strong\u003e \u003cstrong\u003e- Dominant Homozygous for Extension - Black, Bay or Brown - Only the black facto\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003er\u003c\/strong\u003e is expressed. The horse can only transmit the (E) allele \u003c\/span\u003e\u003cspan\u003eE\/E \u003c\/span\u003e\u003cspan\u003eto it offspring. It cannot have foals with basic coat colour Chestnut or Sorrel foals regardless of the color of the mate. The Agouti gene will\u003c\/span\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003edetermine if the basic coat color will be black, bay or brown, unless modified by other color modifying genes. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eE\/e\u003c\/strong\u003e - \u003cstrong\u003eHeterozygous for Extension - Black, Bay or Brown\u003c\/strong\u003e - \u003cspan\u003eBoth red and black factor are expressed. It can transmit either (E) or (e) allele to its offspring. The Agouti gene will determine if the basic coat color will be black, bay or brown, unless modified by other color modifying genes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ee\/e\u003c\/strong\u003e - \u003cstrong\u003eRecessive homozygous for Extension - Chestnut or Sorrel\u003c\/strong\u003e \u003cspan\u003e- Only the red pigment is expressed. The basic coat color is chestnut or sorrel unless modified by other color modifying genes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eEquine coat color is built on one of two possible base pigments: red or black.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Extension gene controls the production of this base pigment (red or black).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll horses will have the genetics for black or red pigment, regardless of their physical appearance. There are a number of dilutions patterns and modifiers, which a horse can carry that affect the base pigment of a horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Extension gene (red factor) has two alternative states (alleles). The dominant allele (E) produces black pigment in the coat. The recessive allele (e) produces red pigment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eRed horses (chestnuts, sorrels, palominos…) are homozygous, that is they have two alleles, for the recessive red allele (e\/e).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eBlack pigmented horses (black, bay, brown, buckskin…) have at least one (E) allele. They can be homozygous (E\/E) or heterozygous (E\/e).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA horse that is homozygous (E\/E) will not produce red offspring, regardless of the color of the mate.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451057856556,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Extension.png?v=1571095160"},{"product_id":"agouti-base-colour","title":"Agouti DNA test - Bay \/ Black","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cspan style=\"color: #000000;\"\u003eAgouti\u003cem\u003e locus \u003c\/em\u003e\u003c\/span\u003e\u003cspan style=\"color: #000000;\"\u003econtrols distribution of black pigment throughout the coat. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003eThis DNA test determine if a horse is A\/A, A\/a or a\/a for the Agouti. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003eTo determine base colour Extension and Agouti testing are needed.  \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eBuy the \u003ca title=\"Base colour test - A and E loci\" href=\"https:\/\/equigerminal.shop\/products\/base-colour-testing-a-and-e-loci?_pos=1\u0026amp;_sid=3064ad34c\u0026amp;_ss=r\"\u003e\u003cstrong\u003eBase colour test\u003c\/strong\u003e\u003c\/a\u003e and get DNA tests for Agouti (A) and Extension (E) \u003cem\u003eloci.\u003c\/em\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample requirements  and submission form\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e30 to 40  hair roots\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood in a K3 EDTA tube \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eGet the sample submission form \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_testing_-_sample_submission_form.pdf?v=1602238338\"\u003ehere\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStandard processing\u003c\/b\u003e - Results in 3-5 working days after sample arrival at the laboratory. Clients organize and support the costs of sending the samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePREMIUM processing\u003c\/b\u003e - Results in 1 days after sample arrival. Includes free express delivery** . The laboratory organizes Express shipping with pick-up of the package at the client's address and delivery at the laboratory.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003e** PREMIUM SERVICES INCLUDE AN EXPRESS SHIPPING DELIVERY FOR EUROPEAN COUNTRIES FROM NON-REMOTE REGIONS.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"https:\/\/www.tnt.com\/dam\/tnt_express_media\/global_media_library\/New_Site_Structure\/Home_Page\/HelpCentre\/Postcodes.pdf\"\u003eCheck here to know if you are in a remote European region.\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFor remote\/outreach regions EXTRA fees are applied.\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg style=\"float: none;\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eAgouti is not shown physically on red (e\/e) horses. Therefore, a breeder might want to test a chestnut base horse to see if it is an Agouti carrier.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eTesting bay horses might be desired to see whether the horse carries one (A\/a) or two (A\/A) copies of the Agouti allele. A homozygous Agouti (A\/A) horse will always pass Agouti to its offspring whereas a heterozygous (A\/a) horse will have a 50% chance of passing on the gene.\u003c\/li\u003e\n\u003cli\u003eAnother reason to test for Agouti might be if there is some doubt whether a black horse is truly black or a very dark bay. The effects of other genes might also make it hard to tell if Agouti is present or not.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003e \u003cstrong\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eA\/A - \u003c\/span\u003e\u003c\/strong\u003eBay or Brown - Dominant Homozygous for Agouti\u003c\/strong\u003e. Black pigment restricted to the points. The horse cannot have black foals regardless of the coat color of the mate. The basic coat color will be bay or brown in the absence of other color modifying genes. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003e \u003cstrong\u003eA\/a - Bay or Brown - Heterozygous for Agouti.\u003c\/strong\u003e Black pigment distributed in point pattern. The horse can transmit either (A) or (a) allele to its offspring. The basic coat color will be bay or brown unless modified by other coat color modifying genes. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"color: #000000;\"\u003e \u003cstrong\u003ea\/a\u003c\/strong\u003e - \u003cstrong\u003eBlack - Recessive homozygous for Agouti\u003c\/strong\u003e. \u003c\/span\u003e\u003cspan\u003e\u003cspan style=\"color: #000000;\"\u003eBlack pigment distributed un\u003c\/span\u003eiformly. The basic coat color will be black in the absence of other coat color modifying genes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Agouti gene controls the distribution of black pigment. This pigment can be either uniformly distributed or distributed to “points” of the body (ear rims, lower legs, mane, tail).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAgouti has been linked to a deletion of 11 nucleotides in the Agouti locus. The 11 nucleotide deletion of this gene is the recessive form of the gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eOnly when the agouti gene is homozygous for the deletion (aa) is the black pigment evenly distributed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHeterozygous (A\/a) or homozygous for the absence of the 11 nucleotide deletion (A\/A) results in point distribution of black pigment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAgouti has no effect on homozygous positive red factor (ee) horses as there has to be black pigment present for agouti to have an effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990990725270,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Agouti.png?v=1662414394"},{"product_id":"cream-dilution","title":"Cream dilution","description":"\u003cp\u003e \u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe cream dilution gene has varying effects on different base colours.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTo obtain the exact ‘type name’ of cream dilute of the horse it is recommended to run this test in conjunction with Extension and Agouti genes.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eTesting is useful where genetic confirmation is required or to define cream dilute horses aside from other genes with similar effects (such as champagne dilution and grey).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eRunning this test will confirm if a horse is cream dilute. As mentioned the cream dilution gene has varying effects on different base colours. To obtain the exact ‘type name’ of cream dilute of the horse (eg.\u003cem\u003e Buckskin\u003c\/em\u003e, \u003cem\u003ePalomino\u003c\/em\u003e, \u003cem\u003eCremello\u003c\/em\u003e…) it is recommended to run this test in conjunction with red factor and agouti.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the Cream dilution gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e - \u003cstrong\u003eNon-dilute\u003c\/strong\u003e. Basic colours are black, bay or chestnut, in the absence of other modifying genes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/Cr\u003c\/strong\u003e – \u003cstrong\u003eDilute\u003c\/strong\u003e. Heterozygous, one copy of the Cream (Cr) allele. \u003cem\u003eChestnut\u003c\/em\u003e is diluted to \u003cem\u003epalomino\u003c\/em\u003e; \u003cem\u003ebay\u003c\/em\u003e is diluted to \u003cem\u003ebuckskin\u003c\/em\u003e and \u003cem\u003eblack\u003c\/em\u003e is diluted to \u003cem\u003esmoky black\u003c\/em\u003e. These colours can be further modified by the actions of other genes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCr\/\u003c\/strong\u003e - \u003cstrong\u003eDouble dilute\u003c\/strong\u003e, two copies of the Cream (Cr) allele. Chestnut is diluted to \u003cem\u003ecremello\u003c\/em\u003e; bay is diluted to \u003cem\u003eperlino\u003c\/em\u003e and black is diluted to \u003cem\u003esmoky cream.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe cream dilution gene affects both red and black pigment and is responsible for ‘diluting’ the carrying horse to lighter coat shades and colours. In many breeds this is often considered a highly desirable trait. Cream dilution is the gene responsible for \u003cem\u003epalominos\u003c\/em\u003e, \u003cem\u003ebuckskins\u003c\/em\u003e, \u003cem\u003ecremellos\u003c\/em\u003e and many more.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses which carry one copy of the cream gene are identified as single dilutes; they are heterozygous for the cream dilution gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIn the simplest case, a \u003cem\u003ebay\u003c\/em\u003e horse with a single copy of cream is known as a \u003cem\u003ebuckskin\u003c\/em\u003e, a single dilute \u003cem\u003eblack\u003c\/em\u003e horse is known as a \u003cem\u003esmoky black\u003c\/em\u003e and a single dilute \u003cem\u003echestnut\u003c\/em\u003e or\u003cem\u003e sorrel\u003c\/em\u003e horse is known as a \u003cem\u003epalomino\u003c\/em\u003e. Single dilute horses have a 50% chance on passing the cream gene on to its offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses which carry two copies of the cream gene are referred to as double dilutes; they are homozygous for the cream dilution gene. A \u003cem\u003ebay\u003c\/em\u003e horse with two copies of cream is known as a \u003cem\u003eperlino\u003c\/em\u003e. A \u003cem\u003eblack\u003c\/em\u003e horse with two copies of cream is known as a \u003cem\u003esmoky cream\u003c\/em\u003e and a \u003cem\u003echestnut\u003c\/em\u003e or \u003cem\u003esorrel\u003c\/em\u003e horse that carries two copies of cream is known as a \u003cem\u003ecremello\u003c\/em\u003e. Double dilute horses will always pass on a copy of the cream gene to its foals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: right;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: right;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: right;\"\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451065557036,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Cream.png?v=1571095139"},{"product_id":"peral-dilution","title":"Pearl dilution","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003c\/div\u003e\n\u003cdiv\u003eThe DNA test is designed to verify the presence of the pearl allele (Prl), a coat color dilution modifier discovered in horses of Iberian origin. This variant produces dilutions of the base color, introducing golden tones to the coat.\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample \u003c\/strong\u003e\u003c\/span\u003e\u003cspan style=\"color: #c739d2;\" color=\"#c739d2\"\u003e\u003cspan style=\"caret-color: #c739d2;\"\u003e\u003cb\u003erequirements \u003c\/b\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e20 to 30 hair roots, or\u003c\/li\u003e\n\u003cli\u003e5 mL of blood in a K3 EDTA tube.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe results are available within 2 to 5 working days.\u003c\/p\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePurpose of the Test\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003ePearl is a rare variant that dilutes the base coat colors in a less pronounced manner than the cream variant (Cr). It can complement the effect of the Cream variant, leading to very diluted coats similar to Cream double dilutes when both are present in heterozygosity. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTesting is crucial for breeding purposes, as heterozygous Pearl horses can produce diluted offspring when bred with another Pearl carrier or a Cream dilute horse. The impact of the Pearl dilution varies based on the horse's base color, affecting the phenotype differently across different base colors.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #06b2ae;\"\u003e \u003cstrong\u003eInterpretation of Results for the Pearl Locus\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong style=\"color: #000000; font-size: 0.875rem;\"\u003e\u003cstrong style=\"color: #000000; font-size: 0.875rem;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e N\/N - Negative for Pearl\u003c\/strong\u003e\u003c\/strong\u003e\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"padding-left: 30px;\"\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eThe horse is genetically negative for the pearl allele, meaning it does not have any copies of this genetic variant. Its phenotype reflects the natural, unaltered base coat color. This horse will not pass the pearl dilution trait to its offspring, ensuring the continuation of the base coat color in the lineage.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong style=\"color: #000000; font-size: 0.875rem;\"\u003eN\/Prl\u003c\/strong\u003e\u003cspan style=\"color: #000000; font-size: 0.875rem;\"\u003e –\u003cmeta charset=\"UTF-8\"\u003e \u003cstrong data-mce-fragment=\"1\"\u003ePositive Heterozygous \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"padding-left: 30px;\"\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eThe horse is positive for the Pearl allele in a heterozygous state, indicating it carries one copy of the pearl variant. \u003c\/span\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cspan style=\"font-size: 0.875rem;\" data-mce-fragment=\"1\"\u003eThis configuration subtly dilutes the base coat color, infusing it with golden tones, although in some instances, the dilution effect may not be visually apparent. \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e As a heterozygous carrier, there's a 50% probability that it will transmit this dilution trait to its offspring, potentially leading to varied coat colors among the progeny.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003ePrl\/Prl -  Positive Homozygous \u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"padding-left: 30px;\"\u003eThe horse is positive for the pearl allele in a homozygous state, carrying two copies of this genetic variant. This genotype manifests in a more noticeable dilution of the coat color, even in the absence of other dilution genes. Being homozygous, the horse will invariably pass the pearl allele to all of its offspring, ensuring the trait's propagation and contributing to the diversity of coat colors in future generations.\u003c\/div\u003e\n\u003cdiv style=\"padding-left: 30px;\"\u003e \u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003eAdditional insights\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cp class=\"p1\"\u003eThe interplay between the Cream and Pearl genes subtly yet significantly affects horse coat colors, particularly evident in horses heterozygous for both genes (N\/Cr + N\/Prl). These horses often resemble double cream dilutes but can be distinguished by slightly darker eye colors and a marginally darker coat. Unlike double cream dilutes, the combined dilution effect of heterozygous Cream and Pearl genes might not be as pronounced, requiring careful observation or genetic testing for accurate identification.\u003cbr\u003e\u003cbr\u003eHomozygous Pearl horses (Prl\/Prl) exhibit a more noticeable dilution, displaying pronounced golden tones in their coats compared to their homozygous Cream counterparts (Cr\/Cr), whose phenotype is lighter. Interestingly, the eye and skin colors in foals—typically blue and pinkish, respectively—tend to darken with age, while the coat lightens.\u003cbr\u003e\u003cbr\u003eThe subtle dilution effects of a single Pearl allele (N\/Prl) often go undetected without genetic analysis, as they minimally alter the horse's appearance. However, the presence of two Pearl alleles (Prl\/Prl) significantly enhances the dilution, affecting not just the coat but also the eye color, with amber or green hues depending on the base coat color.\u003cbr\u003e\u003cbr\u003eIdentified in Iberian breeds like the Purebred Lusitano (PSL) and Purebred Spanish Horse (PRE), and speculated in the Spanish Mustang, the Pearl gene's inclusion in genetic discussions highlights its broad impact across equine breeds. This genetic diversity, particularly when Pearl intersects with Cream, underscores the complexity of equine coat colors and the value of genetic testing for breeders. \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451068309548,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Pearl.png?v=1571095127"},{"product_id":"silver-dilution","title":"Silver dilution (Dapple)","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe genetic test verifies the presence of the\u003cstrong\u003e Silver\u003c\/strong\u003e \u003cspan\u003ecoat dilution modifier.\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThe Silver\u003c\/span\u003e genetic variant is associated with \u003cstrong\u003eMultiple Congenital Ocular Abnormalities\u003c\/strong\u003e (MCOA) in some breeds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan style=\"font-size: 1.4em;\"\u003e \u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the silver gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan class=\"s1\"\u003eN\/ \u003c\/span\u003e\u003c\/strong\u003e– \u003cstrong\u003eNegative for Silver\u003c\/strong\u003e - No evidence of the genetic variant for Silver. No risk to develop \u003cspan\u003e Multiple Congenital Ocular Abnormalities (MCOA) associated to Silver.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eZ\/N\u003c\/strong\u003e - \u003cstrong\u003eHeterozygous for Silver\u003c\/strong\u003e - The Black and Bay basic coat colour will be diluted by Silver. Black-based horses will be chocolate with flaxen mane and tail. Bay-based horses will have pigment on lower legs lightened and flaxen mane and tail. No effect on chestnut color. Moderate risk to develop MCOA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eZ\/\u003c\/strong\u003e – \u003cstrong\u003eHomozygous for Silver\u003c\/strong\u003e - Two copies of altered sequence detected. Black-based horses will be chocolate with flaxen mane and tail. Bay-based horses will have pigment on lower legs lightened and flaxen mane and tail. No effect on chestnut color, but will pass the variant on to 100% of offspring.  Higher\u003cspan\u003e risk to develop severe MCOA.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003eThe Silver dilution behaves as a coat colour \u003cspan\u003edominant trait on bay and black base coat colours. W\u003c\/span\u003e\u003cspan\u003ehile\u003c\/span\u003e chestnut base colour is not affected by the Silver dilution and can pass the variant silently to the offspring. \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIn short, the Silver dilution variant (Z) will only affect coat colour phenotype of black pigmented horses (E\/e or E\/E) and has no effect on red pigmented horses (e\/e). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan\u003eIn addition, the eye disorders associated to Silver genetic variant are incomplete autosomal dominant:  homozygous horses (with two copies of Z)  may be at higher risk of developing severe Multiple Congenital Ocular Abnormalities (MCOA), while heterozygous (with one copy of Z) may develop a milder form of MCOA.  \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003eThe effects of the silver dilution on coat colour gene can vary widely.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe agouti gene affects the coat colour by controlling the distribution of the black pigment whereas the\u003cspan style=\"text-decoration: underline;\"\u003e Silver dilution\u003c\/span\u003e variant dilutes areas of the black pigment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003eDilution by the Silver variant on a horse with a uniform \u003cspan style=\"text-decoration: underline;\"\u003eblack base\u003c\/span\u003e typically involves lightening of the mane and tail and a dilution of the body to a chocolate color, often \u003cspan style=\"text-decoration: underline;\"\u003edappled\u003c\/span\u003e as well.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA \u003cspan style=\"text-decoration: underline;\"\u003eBay horse\u003c\/span\u003e carrying the Silver gene will usually have a lightened mane and tail, as well as lightened lower legs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIt is important to know that although a red horse (e\/e) will not be diluted by the silver variant, it can be a carrier of the genetic variant and thus potentially pass the gene on to its offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSilver dilution has been identified in a number of horse breeds including the Quarter horse, the Rocky Mountain horse, the Icelandic horse, Morgans, Shetland ponies and the Miniature horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eReferences:\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBrunberg, E., Andersson, L., Cothran, G., Sandberg, K., Mikko, S., Lindgren, G.: A missense mutation in PMEL17 is associated with the silver \u003cmark class=\"hilite term-0\"\u003e\u003c\/mark\u003ecoat color in the horse. BMC Genetics 7:46, 2006.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAndersson, L.S., Wilbe, M., Viluma, A., Cothran, G., Ekesten, B., Ewart, S., Lindgren, G.: Equine Multiple Congenital Ocular Anomalies and Silver Coat Colour Result from the Pleiotropic Effects of Mutant PMEL. PLoS One 8:e75639, 2013.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451076272172,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Silver.png?v=1571095115"},{"product_id":"champagne-dilution","title":"Champagne dilution","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the champagne mutation. Champagne \u003c\/span\u003e\u003cspan class=\"s1\"\u003e is a coat dilution modifier.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eEquigerminal offers testing for the dominant champagne gene-mutation. DNA testing may be useful in cases whereby a horse has previously tested negative for cream or silver dilutions, but appears to have a lightened-coat.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eTesting is also used to determine Homozygosity of the champagne gene.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e Results description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the champagne mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e – Non-champagne horse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/Ch\u003c\/strong\u003e – Positive for dominant champagne gene, possessing one inherited copy. Coat will be diluted accordingly. Will pass champagne gene to approximately 50% of the offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCh\/\u003c\/strong\u003e – Positive for dominant champagne gene, possessing two inherited copies. Coat will be diluted accordingly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eChampagne dilution is caused by a dominant gene, meaning that a horse with a single copy of the Champagne gene will have Champagne characteristics.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Champagne dilution gene lightens a horse’s coat color by diluting the pigment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe specific color produced will depend on the horse’s base color: bay coats to a golden brown, black coats can lighten to a dark brown, and chestnut coats to an apricot or gold.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA horse can carry more than one dilution gene which can further affect coat color. Unlike cream dilution, there are no visual differences between a horse with one copy or two copies of Champagne.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAlthough similar to the cream, pearl and dun dilutions, the Champagne gene has certain characteristics that distinguish it from other dilutions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eCommon characteristics of a Champagne horse include pinkish freckled or mottled skin, a shiny coat that is often slightly darker in the winter, and a hazel eye color.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eChampagne horses are typically born with a blue eye color that evolves to a hazel or an amber colour and pink skin that becomes darker and more freckled over time, especially around the eyes and muzzle.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA homozygous Champagne horse will always pass one copy of the Champagne gene to its foal. Heterozygous horses have a 50% chance of passing the gene on to its foals.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451078991916,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Champagne.png?v=1665065800"},{"product_id":"grey-depigmentation","title":"Grey depigmentation","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the grey mutation. \u003c\/span\u003e\u003cspan class=\"s1\"\u003eGrey is the dominant gene responsible for the gradual and progressive de-pigmentation (fading) of the carrying horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis genetic test can help breeders that are interested in specifically breeding grey foals. Homozygous grey specimens are ideal as they will always transmit the grey gene when bred, thus guaranteeing eventual grey progeny.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eFor the breeder that wants to  “breed-out” the grey modifier to gain non-fading foals may hope for heterozygous grey horses.\u003c\/li\u003e\n\u003cli\u003eSome breed-types have a large percentage of grey stock which through historical lineage may harbour colours and dilutions that are ‘hidden’ by the masking effect of the grey.\u003c\/li\u003e\n\u003cli\u003eInsight into a foal’s potential to fade: since grey may cause slow de-pigmentation, it may not be visually apparent whether or not a newborn foal will eventually fade to grey. The de-pigmentation process may take many years and therefore DNA testing is useful in the cases whereby a foal is born of one or more grey parents and verification of the presence of grey is necessary.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the grey mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/\u003c\/strong\u003e – \u003cstrong\u003eNon-grey horse\u003c\/strong\u003e. Negative for grey. Horse will not turn grey.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/N\u003c\/strong\u003e - \u003cstrong\u003eGrey horse.\u003c\/strong\u003e Positive for dominant grey gene, carrying a single inherited copy. Carrier’s coat modified and will eventually become de-pigmented. Heterozygous grey horses are statistically likely to pass the gene to 50% off their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/\u003c\/strong\u003e - \u003cstrong\u003eGrey horse\u003c\/strong\u003e. Positive for dominant grey gene, carrying two inherited copies. Carrier’s coat modified and will eventually become de-pigmented. Homozygous grey horses are genetically bound to pass the gene to 100% of their progeny when bred, so all foals will receive grey and fade-out.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey is the dominant gene responsible for the gradual and progressive de-pigmentation (fading) of the carrying horse. \u003c\/span\u003e\u003cspan class=\"s1\"\u003eGrey cannot be considered a base-color, or a dilution, but rather a gene which slowly removes pigment from the coat. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis gene is considered to be the ‘strongest’ of all coat modifiers, and acts upon any base-color regardless of the carrying horse’s phenotype. The fading process itself may last for years, but once hair is de-pigmented, the horse’s original colouring will never return.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSince grey is a dominant gene, where it is present it is expressed. However, the final phenotype of the carrier will vary from horse to horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSome grey horses fade to full de-pigmentation (almost pure white) whereas others may be ‘fleabitten’. Fleabitten refers to grey horses with tiny non-faded spots or ‘fleabites.’ The grey carrying horse may also experience de-pigmentation of the skin itself, and before skin is fully faded may display ‘mottling’.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eEquine melanomas occur most often in grey horses, and it is expected that at least 80% of grey horses will develop melanoma.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451081711660,"sku":"","price":49.2,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Grey.png?v=1571095092"},{"product_id":"dun-dilution","title":"Dun dilution","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003eDNA\u003cstrong\u003e test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of \u003c\/span\u003e2 mutations of the TBX3 gene responsible for Dun dilution and primitive markings. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThe DNA test that will provide information for both dun dilution (D) and the primitive markings (nd1, nd2). \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #00afab;\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eD\/\u003c\/strong\u003e \u003cstrong\u003e- Homozygous for Dun.\u003c\/strong\u003e The basic coat colour will be diluted by Dun and primitive markings expressed. The Dun genetic variant will be passed on 100% of the offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eD\/nd1 - 1 copy of Dun and one copy of nd1.\u003c\/strong\u003e The basic coat colour will be diluted by Dun and primitive markings expressed. Horse can pass on Dun dilution (50%) or primitive markings without dilution (50%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eD\/nd2\u003c\/strong\u003e \u003cstrong\u003e- 1 copy of Dun and one copy of nd2\u003c\/strong\u003e. Horse will have Dun dilution and express primitive markings. The Dun genetic variant will be passed\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003ewith a 50% chance to the offspring\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003end1\/nd1 - Homozygous for nd1.\u003c\/strong\u003e The basic coat colour will not be diluted but primitive markings are expressed in varying levels. The primitive markings will be passed on 100% of the offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003end1\/nd2\u003c\/strong\u003e \u003cstrong\u003e- 1 copy of nd1 and one copy of nd2.\u003c\/strong\u003e The basic coat colour will not be diluted but primitive markings are expressed in varying levels. The primitive markings will be passed on 50% of the offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cstrong\u003e\u003cspan\u003end2\/nd2 - \u003c\/span\u003e\u003c\/strong\u003eNegative\u003c\/strong\u003e for Dun Dilution and primitive markings.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDun is a dominant dilution gene of equines characterised by lightening of the body color, leaving the head, lower legs, mane and tail undiluted.\u003c\/li\u003e\n\u003cli\u003eDun is also typically characterised by “primitive markings” consisting of a dark dorsal stripe and sometimes leg barring, shoulder stripes and concentric marks on the forehead.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDun is present in many breeds of horses including (but not limited to) Appaloosa, Bashkir Curly, Iberian horse breeds, Icelandic Horse, Mustang, Norwegian Fjord, Paint, Paso Fino, Peruvian Paso, Quarter Horse and several of the pony breeds\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451093704748,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Dun.png?v=1570529267"},{"product_id":"tobiano-coat-pattern","title":"Tobiano coat pattern","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the chromosomal inversion. \u003c\/span\u003e\u003c\/span\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Tobiano coat pattern usually involves some white on all four legs and rounded white spots on the body with sharp, clean edges.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\"\u003eTurnaround time\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis genetic test can confirm is the horse is heterozygous (To\/N) or homozygous (To\/) for the Tobiano gene. For breeding purposes,\u003cstrong\u003e homozygous\u003c\/strong\u003e Tobiano horses are \u003cspan style=\"text-decoration: underline;\"\u003ehighly desirable\u003c\/span\u003e as they are guaranteed to produce Tobiano foals regardless of their mate.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eSince Tobiano is only responsible for the white markings of a so called “colored” horse, the test does not determine the horse’s base-color. This is determined using the extension test. The two tests in conjunction not only verify the likelihood of Tobiano being passed to foals, but also the likelihood the foals will be piebald or skewbald.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the chromosomal inversion and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e – \u003cstrong\u003eNon-tobiano\u003c\/strong\u003e horse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTo\/N\u003c\/strong\u003e – \u003cstrong\u003ePositive\u003c\/strong\u003e for the dominant Tobiano gene mutation, carrier of a single inherited copy of Tobiano. Horse’s base color may be modified to varying degrees by the Tobiano markings.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTo\/\u003c\/strong\u003e – \u003cstrong\u003ePositive\u003c\/strong\u003e for dominant Tobiano gene mutation, carrying two inherited copies of Tobiano. Will always pass Tobiano to foals. For breeding purposes, homozygous Tobiano horses are highly desirable as they are guaranteed to produce Tobiano foals regardless of their mate.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe Tobiano coat pattern usually involves some white on all four legs and rounded white spots on the body with sharp, clean edges.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe head of the horse is usually colored and will not have white caused by the Tobiano gene. The white on the body will generally cross the top-line of the horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAlthough white often incorrectly referred to as adding color it is actually a deletion of color. Tobiano is the result of a chromosomal inversion, affecting regulatory regions of the KIT gene. The Tobiano coat pattern is governed by the dominant KIT gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eOnly one copy of Tobiano gene (To\/N) is required to express Tobiano coat pattern.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHomozygosity of the Tobiano gene (To\/) may show visual clues (“ink spots” or “paw prints”) but only genetic testing will tell you more conclusively that the horse is homozygous for the Tobiano gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eWhen there is no presence of the Tobiano gene (N), the Tobiano coat pattern is not possible.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451094589484,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Tobiano.png?v=1571390930"},{"product_id":"overo-coat-pattern","title":"Overo - coat pattern","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the mutation associated to the Overo. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e Frame Overo is a highly desirable white pattern gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong style=\"color: #c739d2;\"\u003eSample\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe relationship between Lethal White Foal Syndrome (LWFS) and the frame overo coat pattern is not always straightforward. Usually carriers of LWFS are frame overo in pattern, and have 1 copy of the mutated allele (nL). But not all frame overo horses carry the mutated allele, some have the genotype (nn).\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eAnd some horses with other coat patterns (including solid coloured paints and tobiano) have been found to carry the mutated allele.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eIt should also be remembered that not all white foals have the genotype (LL) ,and may not be affected by LWFS.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eResults description\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the mutation associated to the Overo and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cb\u003eN\/\u003c\/b\u003e - \u003c\/span\u003e\u003cstrong\u003eNon-Overo \u003c\/strong\u003ehorse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eO\/N\u003c\/b\u003e - \u003cstrong\u003eFrame Overo \u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003ehorse\u003c\/strong\u003e. Horse is heterozygous for the dominant gene causative of frame Overo. A characteristic Overo coat pattern is present in \u003c\/span\u003e\u003cspan\u003eO\/N \u003c\/span\u003e\u003cspan\u003eall horses with a copy of frame Overo and will pass this allele to 50% of offspring. Matting two Frame Overo horses has a 50% chance to\u003c\/span\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003egenerate Lethal White foals and should be avoided.\u003cbr\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eO\/\u003c\/strong\u003e – \u003cstrong\u003eA Lethal White Foal Syndrome \u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e(LWFS)\u003c\/strong\u003e. Homozygous for frame Overo are lethal and newborns survive less than a week old.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo is a highly desirable white pattern gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAll Frame Overo horses carry a single inherited copy of the Ile118Lys EDNRB mutation. This mutation causes pigment loss, producing white markings on certain areas of the horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eWhile the mutation produces visually desirable horses, it is also linked to a fatal condition known as Lethal White Foal Syndrome (LWFS), whereby a foal is born almost pure white in appearance, and dies within its first few days of life. Correct breeding can avoid this occurrence.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eLWFS occurs when a horse inherits two copies of the mutated gene, one from both parents. Whereas horses with just one copy of the gene will live normally and exhibit the desirable pattern. A horse with two copies of the mutated gene will suffer intestinal abnormalities caused by undeveloped nerves of the foal’s digestive system. These animals die within the first 72 hours of being born and are typically euthanised sooner for humane reasons.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFrame Overo horses which carry just a single copy of the gene, will pass one copy of it to their foals approximately 50% of the time when bred.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eTherefore, when breeding an Overo horse to a solid non-Overo horse, the foal can only inherit one copy. However, if two Overo horses are bred together they could potentially both pass the Overo gene to the foal, meaning it inherits two copies. Horses which inherit two copies of Frame Overo will suffer the Lethal White condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eProper mating must be carried out to ensure that two frame Overo horses do not breed. This will prevent any risk of the foal inheriting two copies of the mutated gene.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451095736364,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Overo.png?v=1662414566"},{"product_id":"leopard-coat-pattern","title":"Leopard, ERU \u0026 CSNB","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant LP gene. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThe LP gene is associated to high risk of Equine Recurrent Uveitis (\u003cstrong\u003eERU\u003c\/strong\u003e) and Congenital Stationary Night Blindness (\u003cstrong\u003eCSNB\u003c\/strong\u003e).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong style=\"color: #c739d2;\"\u003eSample\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant LP Gene (designated LP) and presents results as one of the following: \u003cspan class=\"Apple-converted-space\"\u003e                                                            \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e -\u003cstrong\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eNegative for LP.\u003c\/strong\u003e \u003cspan\u003eAbsence of the dominante LP gene, non spotted horse. \u003c\/span\u003e\u003cspan\u003eLower risk \u003c\/span\u003e\u003cspan\u003eto develop Equine Recurrent Uveitis \u003c\/span\u003e\u003cspan\u003e(ERU) \u003c\/span\u003e\u003cspan\u003eand Congenital \u003c\/span\u003e\u003cspan\u003eN\/ \u003c\/span\u003e\u003cspan\u003eStationary Night Blindness (\u003c\/span\u003e\u003cspan\u003eCSNB) \u003c\/span\u003e\u003cspan\u003eassociated to Leopard.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eLP\/N\u003c\/strong\u003e - \u003cstrong\u003eP\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eositive heterozygous for LP.\u003c\/strong\u003e \u003cspan\u003ePresence of one copy of the incomplete dominant LP gene responsible spotted coat (Appaloosa coat pattern). \u003c\/span\u003eHorses \u003cspan\u003ehave high risk \u003c\/span\u003e\u003cspan\u003eto develop Equine Recurrent Uveitis (\u003c\/span\u003e\u003cspan\u003eERU). \u003c\/span\u003e\u003cspan\u003eThe horse can pass the LP gene to 50% of their progeny when bred.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eLP\/\u003c\/strong\u003e -\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003ePositive homozygous for LP\u003c\/strong\u003e. \u003cspan\u003ePresence of two copies of the incomplete dominant LP gene responsible for spotted coat (Appaloosa coat pattern). \u003c\/span\u003eAdditionally horses have \u003cspan\u003ehighest risk \u003c\/span\u003e\u003cspan\u003eto develop Equine Recurrent Uveitis (\u003c\/span\u003e\u003cspan\u003eERU) \u003c\/span\u003e\u003cspan\u003eand Congenital Stationary Night Blindness (\u003c\/span\u003e\u003cspan\u003eCSNB). \u003c\/span\u003e\u003cspan\u003eThe horse will \u003c\/span\u003e\u003cspan\u003eLP\/LP \u003c\/span\u003e\u003cspan\u003epass the LP gene to 100% of its offspring. Risk for ERU associated to LP is evaluated LP\/LP \u0026gt; LP\/N \u0026gt; N\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eAdditional information\u003c\/span\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"s1\"\u003eThe white patterns called Leopard Complex (LP), also know as Appaloosa spotting, has an high variable expression ranging from absent to extreme white patterning. \u003c\/span\u003e\u003cbr\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"s1\"\u003e\u003cspan\u003eThe expression of Leopard Complex includes several effects on the horse's coat: speckled\/mottled skin around the eyes, muzzle, anus, genitalia, and eyes, and progressive roaning (varnish roan) of pigmented coat areas with age. White spotting may also be present, with pigmented leopard spots tending to occur on the white spotting background of heterozygous horses. \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe inheritance of this coat colour trait is incomplete dominant. The amount of white present is not dosage related, such that homozygous horses can have minimal expression of white patterning. The variability in the amount of white on leopard complex patterned horses is controlled by other genes, one of which is \u003ca href=\"https:\/\/equigerminal.shop\/products\/patn1-coat-pattern?_pos=1\u0026amp;_sid=b36c4afb5\u0026amp;_ss=r\"\u003ePattern 1. \u003c\/a\u003e \/PATN1, the coat pattern spotting. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eHorses that are homozyous for the Leopard Complex  develop \u003cstrong\u003eCongenital Stationary Night Blindness (CSNB)\u003c\/strong\u003e which is the inability to see in low to no-light conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEquine Recurrent Uveitis (ERU), \u003c\/strong\u003ealso known as moon blindness, is also associated to the LP genetic variant. ERU is characterised by repeated episodes of inflammation of the iris, ciliary body, and choroid. The cumulative effects of the immune mediated process can lead to glaucoma, cataracts, and complete loss of vision. \u003c\/p\u003e\n\u003cp\u003eERU is the most common cause of blindness in horses. The LP test is the most effective genetic test to ascertain risk for ERU. \u003c\/p\u003e\n\u003cp\u003eRisk for ERU based on this genetic test can be evaluated as \u003cstrong\u003eLP\/LP \u0026gt; LP\/N \u0026gt; N\/N. \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHorses homozygous for LP mutation are the highest risk of developing ERU.\u003c\/li\u003e\n\u003cli\u003eHorses heterozygous for LP mutation are at higher risk of developing ERU than those with the mutation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cspan class=\"s1\"\u003eThe LP variant is closely identified to the Appaloosa breed, though has indicated has a very ancient genetic variant. European cave paintings have recorded spotted horses and archaegenetic studies have identified the LP genetic variant in European horses of the Pleistocene and Copper Age.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"s1\"\u003eThe LP genetic variant can be found in many different breeds such as pony of Americas breeds, British Spotted Pony, Knabstrupper, Noriker, Tannu Tuva Pony, American Miniature Horse, Mustang breeds and Tiger horses . \u003c\/span\u003e\u003cbr\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eReferences\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBellone, R.R., Holl, H., Setaluri, V., Devi, S., Maddodi, N., Archer, S., Sandmeyer, L., Ludwig, A., Foerster, D., Pruvost, M., Reissmann, M., Bortfeldt, R., Adelson, D.L., Lim, S.L., Nelson, J., Haase, B., Engensteiner, M., Leeb, T., Forsyth, G., Mienaltowski, M.J., Mahadevan, P., Hofreiter, M., Paijmans, J.L., Gonzalez-Fortes, G., Grahn, B., Brooks, S.A.: Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse. PLoS One 8:e78280, 2013. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBellone RR. Genetic Testing as a Tool to Identify Horses with or at Risk for Ocular Disorders. \u003ci\u003eVet Clin North Am Equine Pract\u003c\/i\u003e. 2017;33(3):627–645. doi:10.1016\/j.cveq.2017.08.005\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePruvost M. et al.. Genotypes of predomestic horses match phenotypes painted in Paleolithic works of cave art. Proc. Natl. Acad. Sci. 108, 18626–18630 (2011). [\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3219153\/\"\u003ePMC free article\u003c\/a\u003e] [\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22065780\"\u003ePubMed\u003c\/a\u003e] [\u003ca href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Proc.+Natl.+Acad.+Sci.\u0026amp;title=Genotypes+of+predomestic+horses+match+phenotypes+painted+in+Paleolithic+works+of+cave+art\u0026amp;author=M.+Pruvost\u0026amp;volume=108\u0026amp;publication_year=2011\u0026amp;pages=18626-18630\u0026amp;pmid=22065780\u0026amp;\"\u003eGoogle Scholar\u003c\/a\u003e]\u003c\/span\u003e\u003c\/p\u003e\n\u003cbr\u003e\u003cbr\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451098062892,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Leopard.png?v=1571095049"},{"product_id":"patn1-coat-pattern","title":"PATN1 - coat pattern spotting","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant (PATN1) mutation. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e20 to 30 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant (PATN1) mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/ \u003c\/strong\u003e- \u003cstrong\u003eNegative\u003c\/strong\u003e for PATN1.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eAbsence of the dominante PATN1 gene - non spotted horse.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003ePATN1\/N\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003ePositive heterozygous for PATN1 (Dominant)\u003c\/strong\u003e\u003cspan\u003e. Presence of one copy of the dominant PATN1 gene responsible spotted coat. The horse can \u003c\/span\u003epass the PATN1 variant to 50% of their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003ePATN1\/\u003c\/strong\u003e -\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003e\u003cstrong\u003ePositive homozygous for PATN1 (Dominant)\u003c\/strong\u003e. Presence of two copies of the dominant PATN1 gene responsible for spotted coat.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse will pass the PATN1 gene to 100% of its offspring.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451099439148,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/PATN1.png?v=1571095039"},{"product_id":"coat-colour-profile","title":"Coat colour profile","description":"\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cspan color=\"#c739d2\" style=\"color: #c739d2;\"\u003e8 panel genetic test for \u003cspan style=\"caret-color: #c739d2;\"\u003ecoat colour \u003c\/span\u003ewith results in 5 to 10 working days.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIncludes \u003cstrong\u003e8 coat colour genetic markers:  \u003c\/strong\u003e2 base colour - \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/agouti-base-colour\"\u003eAgouti\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/extension-base-colour\"\u003eExtension\u003c\/a\u003e; 5 dilutions - \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/cream-dilution\"\u003eCream\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/peral-dilution\"\u003ePearl\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/champagne-dilution\"\u003eChampagne\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/silver-dilution\"\u003eSilver\u003c\/a\u003e and \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/dun-dilution\"\u003eDun\u003c\/a\u003e (D, nd1, nd2) and the \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/grey-depigmentation\"\u003eGrey\u003c\/a\u003e* (G\/G, G\/N or N\/N) depigmentation gene.\u003c\/li\u003e\n\u003cli\u003eOur Grey test in panels provide the number of copies of the \u003cstrong\u003eGrey gene\u003c\/strong\u003e (G\/G, G\/N, N\/N)\u003c\/li\u003e\n\u003cli style=\"font-weight: bold;\"\u003e\n\u003cp\u003eA Genetic Colour Certificate - Coat Genotype and Offspring Prediction\u003cspan class=\"Apple-converted-space\"\u003e of coat colour is provided\u003c\/span\u003e\u003c\/p\u003e\n\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample type:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood  (K3 EDTA tube)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e5 to 10 working days\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDNA tests for coats can be an important tool for selection, elimination of coat-related diseases and enhancing your stud farm.\u003c\/li\u003e\n\u003cli\u003eThere are various coat colours and tones in the horse species. Judging coat colour by eye is always subjective and can be influenced by a number of environmental factors (light exposure, time of year and feeding) and it doesn’t allow us to predict with any confidence that the “colour” will be passed down. Genetic determination of coat colour can be done correctly in a laboratory using DNA tests. This method allows us to determine with rigour and objectivity the horse´s coat colour and also forecast the potential transmission of “colour” to offspring.\u003c\/li\u003e\n\u003cli\u003eCurrently more than 16 gene variants have been identified that can influence this phenotypic characteristic.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451114545196,"sku":"","price":184.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/CoatcolourProfile.png?v=1771413862"},{"product_id":"melanoma-dermal-melanoma","title":"Melanoma","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e2 DNA tests that can help to predict the possible type of incidence for developing  dermal melanomas on grey horses.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis 2 DNA tests for melanoma confirms if the grey horse is heterozygous (G\/N) or homozygous (G\/) for the Grey gene and if is Homozygous for non-agouti (a\/a).\u003c\/span\u003eThe results can predict the type incidence for developing dermal melanomas.  \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe genetic profile test verifies the genotype of the Grey and Agouti genes, and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\u003cspan class=\"s1\"\u003eMelanoma incidence risk\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cstrong\u003eG\/N\u003c\/strong\u003e + \u003c\/span\u003e\u003cstrong\u003eA\/a\u003c\/strong\u003e or \u003cstrong\u003eA\/A\u003c\/strong\u003e – \u003cstrong\u003eModerate incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/N\u003c\/strong\u003e + \u003cstrong\u003ea\/a\u003c\/strong\u003e – \u003cstrong\u003eModerate to high incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/G\u003c\/strong\u003e + \u003cstrong\u003eA\/a\u003c\/strong\u003e or \u003cstrong\u003eA\/A\u003c\/strong\u003e – \u003cstrong\u003eHigh incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eG\/G\u003c\/strong\u003e + \u003cstrong\u003ea\/a\u003c\/strong\u003e – \u003cstrong\u003eVery high incidence\u003c\/strong\u003e of dermal melanomas.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMost melanomas found in horses are benign.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eOnce present these benign types of melanoma are not aggressive in their growth and may progress over several years requiring little treatment. A melanoma is one of the most common skin tumors seen in a horse or pony.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey horses have a high incidence of dermal melanomas that are commonly seen around the tail and head. Over 80% of Grey horses older than 15 years will develop melanoma.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey homozygotes are more likely to develop melanoma than heterozygotes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGrey horses that are homozygous for non-agouti (aa) genotype at the Agouti locus, also have a higher risk for melanoma. Many Grey horses show depigmentation of the skin around the eyes, mouth and anus but there are no health risks associated with this condition.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMalignant melanomas in horses can cause severe problems and can be life-threatening. Problems develop when melanomas are present internally or if they become so large that they ulcerate, bleed and become infected.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eEquine melanomas sometimes grow so large that they can cause severe weight loss and\/or colic. If a melanoma is situated on the head in an area where a bridle, saddle, head collar or rug might rub, it will be uncomfortable for the horse, potentially causing behavioural problems. Infections can also occur.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451118936108,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Melanoma.png?v=1571095012"},{"product_id":"severe-combined-immunodeficiency-scid","title":"SCID Severe Combined Immunodeficiency","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003e\u003cspan class=\"s1\"\u003eDNA test\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eDNA test for the Severe Combined Immunodeficiency (SCID). \u003c\/span\u003e\u003cspan class=\"s1\"\u003eSCID is an inherited disease seen in pure and part-bred Arab horses.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe DNA test for SCID helps breeders to identify the animals that are carriers of the SCID mutation. This information allows breeders to prevent two carriers from breeding, which reduce the chances of producing an SCID foal.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eContinued breeding of horses that are carriers of the SCID gene is now possible without the worry of producing SCID foals. For example, carrier stallions that possess highly desirable traits can now be selectively bred to clear (homozygous normal) mares (and vice versa). The resulting foals would have an equal chance of being a carrier or clear of SCID, but would definitely not be affected.\u003c\/li\u003e\n\u003cli\u003eThe foals could be tested anytime after birth to determine their SCID genotype and future matings could be rationally planned.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence recessive SCID mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003cspan class=\"s1\"\u003enn \u003c\/span\u003e\u003c\/strong\u003e– \u003cstrong\u003eNon-carrier\u003c\/strong\u003e of the SCID gene.Tested negative for the SCID mutation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003enSCID \u003c\/strong\u003e– Heterozygous horse for SCID gene, both the normal and SCID alleles were detected. The horse is a carrier of SCID genetic disorder and there is a 50% chance this horse will pass a SCID allele to its offspring\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSCID SCID\u003c\/strong\u003e – Carrier of two copies of the SCID gene. Homozygous horse for SCID mutation. The horse is affected with the SCID genetic disorder.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSevere Combined Immunodeficiency Disease (SCID) is an inherited disease seen in pure and part-bred Arab horses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAnimals with this inherited condition have an enhanced susceptibility to infection and first show signs of disease at between two days and eight weeks of age. Clinical diagnosis of the disease is not straightforward as the symptoms, such as raised temperature, respiratory complications and diarrhoea, are typical of new-born foals with a range of infections.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFoals affected by SCID always die from the disorder within the first six months of life. This happens regardless of the level of veterinary care. SCID is therefore a distressing condition for the effected animal and the owners or caregivers, and results in financial loss due to dead foals and veterinary expenses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe disorder is recessive, which means that a horse must be homozygous positive or have two copies of the defective gene to suffer from the disease. Consequently both the sire and the dam must possess at least one copy of the mutated gene in order for the offspring to be afflicted. Offspring born with one copy of the defective gene and one non-defective copy are considered a carrier and have a 50% chance of passing the defective gene on.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA number of studies have attempted to estimate the frequency of SCID carriers in the Arab horse population. Most sources speculate that the percentage of Arab foals which die of SCID is 2-3%.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIf breeding is random then it would imply that roughly 28-35% of Arab horses are carriers. However, most breeding is rather selective, making the true frequency of carriers in the population somewhat unclear.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451223236652,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/SCID.png?v=1571095001"},{"product_id":"cerebellar-abiotrophy","title":"Cerebellar abiotrophy - CA","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e for the Cerebellar Abiotrophy (CA) – Pure and part-bred Arab horses. This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e test verifies the presence of the recessive CA mutation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis DNA test determines CA clear, carrier or affected status. Informed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eCA is sometimes confused with Wobbler’s syndrome, Equine Protozoal Myeloencephalitis (EPM) and injury-related problems, such as a concussion, so this DNA test could help on the diagnostic.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive CA mutation and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e –\u003cstrong\u003e Negative for CA\u003c\/strong\u003e. Absence of the allele responsible for CA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/CA\u003c\/strong\u003e \u003cstrong\u003e– Carrier - Positive heterozygous for CA.\u003c\/strong\u003e Presence of one copy of the allele responsible for CA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is a carrier for CA disorder and can pass on a copy of CA allele to 50% of their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCA\/\u003c\/strong\u003e–\u003cstrong\u003e Affected - Positive Homozygous for CA\u003c\/strong\u003e. Presence of two copies of the allele responsible for CA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected by\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eCA disorder and can pass the CA allele to 100% of their progeny when bred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eCerebellar Abiotrophy (CA), is a genetic neurological disease in certain species of animals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe disorder manifests itself when Purkinje cells, the neurons that affect balance and coordination, are present in the cerebellum of the brain.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis condition known to affect Arabian horses as well as Miniature horses, the Gotland Pony and possibly the Oldenburg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eIn most cases, foals appear normal at birth, and symptoms generally become noticeable after four months. There have been reported cases where the condition was observed shortly after birth, while others report symptoms developing after the first year.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses affected with CA tend to startle easily and often fall. Common symptoms include head tremor, a lack of balance and other neurological issues.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAffected horses may develop a wide-based stance of the forelegs and difficulty rising from a reclining position. In horses, CA is believed to be linked to an autosomal recessive gene. This means that it is not sex-linked and the allele has to be carried and passed on by both parents in order for an affected animal to be born.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHorses that only carry one copy of the gene may pass it on to their offspring, despite being perfectly healthy themselves and having no symptoms of the disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eBecause the disorder is recessive, the allele for CA may pass through multiple generations before it is expressed.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451250958380,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Cerebellar_Ab.png?v=1665065799"},{"product_id":"hyperkalemic-periodic-paralysis-hypp","title":"HYPP Hyperkalemic Periodic Paralysis","description":"\u003cp\u003e\u003cspan style=\"font-size: 1.4em;\" class=\"s1\"\u003eDNA test for the Hyperkalemic Periodic Paralysis Disease (HYPP). \u003c\/span\u003e\u003cspan style=\"font-size: 1.4em;\" class=\"s1\"\u003eThis DNA test verifies the presence of the recessive HYPP gene.\u003c\/span\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\" color=\"#c739d2\"\u003eSample \u003cspan style=\"caret-color: #c739d2;\"\u003erequirements\u003c\/span\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood in K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg style=\"float: none;\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis genetic test helps breeders to identify horses that carrying the HYPP recessive gene. Informed choices can be made for breeding selections, and prevent the born of affected foals. \u003c\/span\u003eAll offspring of Impressive should be tested for HYPP.\u003c\/li\u003e\n\u003cli\u003eBecause HYPP is dominant disorder, the effects of it can also be transposed to other breeds of horses when intermixing occurs. This test is important in preserving the inherited health of all horses.\u003c\/li\u003e\n\u003cli\u003eHorses with suspicious symptoms of the disease should also be tested.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive HYPP gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e –  \u003cstrong\u003eNormal - \u003c\/strong\u003eAbsence of the allele responsible for HYPP.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/H\u003c\/strong\u003e – \u003cstrong\u003eAffected - Positive heterozygous for HYPP.\u003c\/strong\u003e Presence of one copy of the allele responsible for HYPP. The horse is affected with the HYPP disorder and there is a 50% chance this horse will pass a HYPP allele to its offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eH\/\u003c\/strong\u003e \u003cstrong\u003e– Affected- Positive homozygous for HYPP\u003c\/strong\u003e. Presence of two copies of the allele responsible for HYPP. The horse is affected with the HYPP disorder and there is a 100% chance this horse will pass a HYPP allele to its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHyperkalemic Periodic paralysis (HYPP) is an inherited disease of the muscle, which is caused by an inherited genetic mutation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA point mutation in DNA exists in the sodium channel gene, which codes for an abnormal channel to be expressed in skeletal muscle. This mutation is passed on to offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSodium channels are “pores” in the muscle cell membrane which control contraction of the muscle fibers. When the defective sodium channel gene is present, the channel becomes “leaky” and makes the muscle overly excitable and contract involuntarily.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe channel become “leaky” when potassium levels fluctuate in the blood. This may occur with fasting followed by consumption of a high potassium feed such as alfalfa. Hyperkalemia, which is an excessive amount of potassium in the blood, causes the muscles in the horse to contract more readily than normal. This makes the horse susceptible to sporadic episodes of muscle tremors or paralysis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSeverity of attacks varies from unnoticeable to collapse or sudden death. The cause of death is usually respiratory failure and\/or cardiac arrest.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis genetic defect has been identified in offspring of the American Quarter Horse sire, Impressive. To date, confirmed cases of HYPP have been restricted to descendants of this horse. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHYPP is a dominant disorder meaning both homozygous positive (HH) and heterozygous (nH) horses will be affected. Only homozygous negative (nn) horses are not affected by HYPP.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451379081260,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HYPP.png?v=1571094950"},{"product_id":"hereditary-equine-regional-dermal-asthenia-herda","title":"HERDA Hereditary Equine Regional Dermal Asthenia","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for Hereditary Equine Regional Dermal Asthenia (HERDA). This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e test verifies the presence of the recessive HERDA gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis DNA test helps breeders to identify horses that carrying the HERDA recessive mutation. \u003c\/span\u003eInformed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive HERDA gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003cstrong\u003eNegative\u003c\/strong\u003e for HERDA. Absence of the defective gene responsible for HERDA.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/HERDA\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eCarrier - Positive heterozygous for HERDA\u003c\/strong\u003e. Presence of one copy of the allele responsible for HERDA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is a carrier for HERDA and can pass on a copy of HERDA allele to their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eHERDA\/ -\u003c\/strong\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003ePositive Homozygous for HERDA\u003c\/strong\u003e. Presence of two copies of the allele responsible for HERDA.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected by\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eHERDA disorder and can pass the HERDA allele to 100% of their progeny when bred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHereditary equine regional dermal asthenia (HERDA) is a genetic skin disease predominantly found in the American Quarter Horse. Within the breed, the disease is prevalent in particular lines of cutting horses. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHERDA is characterised by hyper-extensible skin, scarring, and severe lesions along the back of affected horses. Affected foals rarely show symptoms at birth. The condition typically occurs by the age of two, most notably when the horse is first being broke to saddle. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThere is no cure, and the majority of diagnosed horses are euthanised because they are unable to be ridden and are inappropriate for future breeding. HERDA has an autosomal recessive mode of inheritance and affects stallions and mares in equal proportions.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451396677676,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HERDA.png?v=1571094928"},{"product_id":"congenital-myotonia-cm","title":"Congenital Myotonia - CM","description":"\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Congenital Myotonia (CM). \u003c\/span\u003e\u003cspan class=\"s1\"\u003eThis test verifies the presence of the recessive \u003cem\u003ecm\u003c\/em\u003e gene.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood in a K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg style=\"float: none;\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis genetic test helps breeders to identify horses that carrying the \u003cem\u003ecm\u003c\/em\u003e recessive mutation. \u003c\/span\u003eInformed choices can be made for breeding selections, and prevent the born of affected foals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive \u003cem\u003ecm\u003c\/em\u003e gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cspan class=\"s1\"\u003e\u003cb\u003eN\/ -\u003c\/b\u003e \u003c\/span\u003e\u003cstrong\u003eNormal\u003c\/strong\u003e\u003cspan class=\"s2\"\u003e for Congenital Myotonia (CM).\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eAbsence of the affected variant responsible for Congenital Myotonia\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eN\/cm \u003c\/strong\u003e- \u003cstrong\u003eCarrier \u003c\/strong\u003eof Congenital Myotonia (CM). Presence of one copy of the genetic variant causative of Congenital Myotonia. The horse is \u003cspan class=\"s3\"\u003eclinical healthy \u003c\/span\u003e\u003cspan class=\"s2\"\u003eand can pass the genetic variant responsible for CM to 50% of their progeny when bred.\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003ecm\/ - Affected\u003c\/strong\u003e\u003c\/span\u003e\u003cspan class=\"s2\"\u003e\u003cspan style=\"color: #000000;\"\u003e by CM. Presence of two copies of the genetic variant causativ\u003c\/span\u003ee of Congenital Myotonia. The horse is \u003c\/span\u003e\u003cspan class=\"s3\"\u003eaffected \u003c\/span\u003e\u003cspan class=\"s2\"\u003ewith Congenital Myotonia and will pass genetic variant to 100% of its offspring.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eCongenital Myotonia is an inherited neuromuscular disorder characterised by the slow relaxation of muscles after voluntary contraction or electrical stimulation.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eThis disorder has been identified in New Forest ponies and it is caused by an autosomal recessive mutation, which is responsible for the function of chloride ion channels in the skeletal muscle.\u003c\/li\u003e\n\u003cli\u003eCarriers of the mutation appear normal, but when two carriers are mated, a 25 percent chance exists that an affected foal will be produced.\u003cspan class=\"s1\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eAffected foals appear normal at birth. The first symptoms are recurrent episodes of recumbency and difficulty rising to its feet as a result of muscle stiffness. They occur during the first weeks of age and usually increase in the following months.\u003c\/li\u003e\n\u003cli\u003ePicking up the limbs is not possible because of the muscle rigidity. The eye-bulb may be retracted due to the myotonia.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451405819948,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Myotonia_C..png?v=1571094917"},{"product_id":"polysaccharide-storage-myophaty-type-2-pssm2","title":"MIM (PSSM2) DNA Test - 6 variant panel","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eMIM (PSSM2) DNA Test\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eEnsure the Health and Performance of Your Horses with Accurate MIM Testing.\u003c\/strong\u003e Our DNA test identifies the presence of genetic variants associated with Muscle Integrity Myopathy (MIM), formerly known as PSSM2, which affects muscle function and structure.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Requirements\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e30 to 40 hair roots - envelope\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003eup to 15 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test identifies six genetic variants that predispose horses to developing symptoms of Muscle Integrity Myopathy:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eP2:\u003c\/strong\u003e Myotilinopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP3:\u003c\/strong\u003e Filaminopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP4:\u003c\/strong\u003e Myozenin-3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP8:\u003c\/strong\u003e PYROXD1-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePx:\u003c\/strong\u003e CACNA2D3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eK1:\u003c\/strong\u003e COL6A3-Myopathy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eGenetic Inheritance\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eMuscle Integrity Myopathy (MIM) is caused by a hereditary predisposition involving multiple genetic variants. These variants disrupt the structure and function of muscle fibers, leading to symptoms such as muscle stiffness, unexplained lameness, and difficulty building muscle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eClinical Signs and Affected Breeds\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eSymptoms of MIM can vary widely among horses and include unexplained lameness, muscle stiffness, difficulty with gait changes, reluctance to move, muscle atrophy, and behavioral changes. Almost any breed can be affected, with common occurrences in breeds like Quarter Horses, Warmbloods, and Thoroughbreds.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cp\u003eTesting for MIM is crucial for breeders and owners to make informed decisions. By identifying carriers of the genetic variants, breeding choices can be optimized to prevent the spread of these disorders. Additionally, knowing a horse's genetic status can help manage and mitigate symptoms through tailored exercise and feeding protocols.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv id=\"learn-more-content\" class=\"expandable\"\u003e\n\u003ch3 class=\"section-title\"\u003eDetailed Results Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will indicate the presence of the following genetic variants:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eP2:\u003c\/strong\u003e Myotilinopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP3:\u003c\/strong\u003e Filaminopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP4:\u003c\/strong\u003e Myozenin-3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP8:\u003c\/strong\u003e PYROXD1-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePx:\u003c\/strong\u003e CACNA2D3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eK1:\u003c\/strong\u003e COL6A3-Myopathy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eMuscle Integrity Myopathy (MIM) is a genetic disorder that disrupts muscle function and structure, leading to various clinical signs. While it is not possible to cure genetic disorders, optimized management through diet and exercise can help mitigate symptoms, allowing horses to lead normal lives.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\nGeneratio. \u003ca href=\"https:\/\/www.generatio.de\/mim-pssm2\" target=\"_blank\"\u003eMuscle Integrity Myopathy in Horses\u003c\/a\u003eEquiSeq. \u003ca href=\"https:\/\/www.equiseq.com\/learn_pssm2\" target=\"_blank\"\u003ePolysaccharide Storage Myopathy type 2 (PSSM2)\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\u003c\/p\u003e\n\u003cdiv id=\"faq-content\" class=\"expandable\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by MIM?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAlmost any breed can be affected by MIM, with common occurrences in breeds like Quarter Horses, Warmbloods, and Thoroughbreds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is MIM inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMIM is caused by multiple genetic variants that disrupt muscle structure and function. These variants are inherited and can predispose horses to developing symptoms of exertional myopathy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can MIM be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile genetic disorders cannot be cured, their symptoms can often be managed through optimized feeding and exercise protocols. Identifying genetic variants through testing allows for tailored management strategies to mitigate symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Generatio","offers":[{"title":"Default Title","offer_id":29451457724460,"sku":"","price":357.32,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/MIMPSSM2.png?v=1716904823"},{"product_id":"glycogen-branching-enzyme-deficiency-gbed","title":"GBED Glycogen Branching Enzyme Deficiency","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Glycogen Branching Enzyme Deficiency (GBED). This\u003c\/span\u003e\u003cspan class=\"s1\"\u003e DNA test verifies the presence of the\u003cstrong\u003e recessive GBED allele\u003c\/strong\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThis DNA test identify \u003cstrong\u003einapparent carriers\u003c\/strong\u003e of the GBED fatal disorder. \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eIn \u003cstrong\u003ebreeding selection\u003c\/strong\u003e is recommended to avoid the crossbreeding of two GBED inapparent carriers to prevent\u003cem\u003e in utero\u003c\/em\u003e abortion of foetus and the birth of foals affected by GBED.\u003c\/span\u003e \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003eTo confirm GBED in affected foals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDNA testing provide important tools for \u003cstrong\u003einformed choices\u003c\/strong\u003e about breeding selections to prevent abortion and the birth of affected foals.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e \u003cstrong\u003eFrequency and affected breeds\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMore frequent in Paint Horses and Quarter horses related breeds.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eA prevalence of  7,1% and 8,3% in the Paint and Quarter Horse breeds, respectively (Wagner et al., 2006).\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the\u003cstrong\u003e recessive GBED alleles\u003c\/strong\u003e and presents results as one of the following: \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003cstrong\u003eNegative\u003c\/strong\u003e for GBED. Absence of the defective allele responsible for GBED.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGBED\/N\u003c\/strong\u003e - \u003cstrong\u003eCarrier - Positive heterozygous for GBED\u003c\/strong\u003e. Presence of one copy of the allele responsible for GBED.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is a carrier for GBED and can pass on a copy of GBED allele to their progeny when bred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGBED\/ -\u003cspan class=\"Apple-converted-space\"\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003eAffected - Positive Homozygous for GBED\u003c\/strong\u003e. Presence of two copies of the allele responsible for GBED.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe animal is affected by GBED disorder. GBED is lethal causing abortion and\/or\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eneonatal mortality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGlycogen Branching Enzyme Deficiency (GBED) \u003cstrong\u003efatal condition\u003c\/strong\u003e caused by an \u003cstrong\u003eautosomal recessive\u003c\/strong\u003e genetic disorder that results in the bodies' inability to properly store sugar in the glycogen form.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eIn a \u003cstrong\u003enormal horse\u003c\/strong\u003e, the body stores sugar as energy by converting glucose to glycogen.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eThis \u003cstrong\u003egenetic disorder\u003c\/strong\u003e  affects the production of the enzyme needed to branch the glycogen structure, preventing the horse from being able to adequately store sugar in the glycogen form. This means that the horse will not be able to store enough energy to fuel important organs, such as the muscles and brain.\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eUnfortunately, \u003cstrong\u003eGBED is always fatal. \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eGBED often causes the foetus to be aborted \u003ci\u003ein utero. \u003c\/i\u003eWhen born \u003c\/span\u003e\u003cspan class=\"s1\"\u003emost affected foals will die in the first weeks of age\u003cstrong\u003e.\u003c\/strong\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003eResearch studies showed that as many as 2,5% of aborted Quarter Horse foetus were homozygous for the GBED mutation \u003cspan\u003e(Wagner et al., 2006). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eFoals born which are affected by GBED suffer from a range of clinical signs associated with this lack of sugar, such as low energy, weakness and difficulty rising.  \u003c\/span\u003e\u003cspan class=\"s1\"\u003eOther clinical signs include low body temperature, contracted muscles, seizures, and sudden death.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eREFERENCES\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTryon RC, Penedo MC, McCue ME, Valberg SJ, Mickelson JR, Famula TR, Wagner ML, Jackson M, Hamilton MJ, Nooteboom S, Bannasch DL.\u003cstrong\u003e Evaluation of allele frequencies of inherited disease genes in subgroups of American Quarter Horses\u003c\/strong\u003e. J Am Vet Med Assoc. 2009 Jan 1;234(1):120-5. doi: 10.2460\/javma.234.1.120. PubMed PMID: 19119976.DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.2460\/javma.234.1.120\" ref=\"aid_type=doi\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e10.2460\/javma.234.1.120\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eWagner ML, Valberg SJ, Ames EG, Bauer MM, Wiseman JA, Penedo MC, Kinde H, Abbitt B, Mickelson JR. \u003cstrong\u003eAllele frequency and likely impact of the glycogen branching enzyme deficiency gene in Quarter Horse and Paint Horse populations.\u003c\/strong\u003e J Vet Intern Med. 2006 Sep-Oct;20(5):1207-11. PubMed PMID: 17063718.DOI:\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1892\/0891-6640(2006)20%5B1207:afalio%5D2.0.co;2\" ref=\"aid_type=doi\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e10.1892\/0891-6640(2006)20[1207:afalio]2.0.co;2\u003c\/a\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451474927660,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/GBED.png?v=1571094714"},{"product_id":"advanced-profile-10-genetic-disorders","title":"DNA Disorder-Free Certified","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003cmeta name=\"description\" content=\"Ensure your horse's lineage is free from genetic disorders with our Certified DNA Disorder-Free Lines test. Certify your horse against 10 genetic disorders.\"\u003e \u003cmeta name=\"keywords\" content=\"DNA testing, horse genetics, genetic disorders, horse breeding, SCID, LFS, CA, PSSM1, HYPP, GBED, HERDA, MH, CM, WFFS\"\u003e \u003cmeta name=\"author\" content=\"Equigerminal\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eCertified DNA Disorder-Free Lines\u003c\/h2\u003e\n\u003cp class=\"highlight\"\u003eEnsure your horse's lineage is free from genetic disorders with our comprehensive DNA testing panel. Certify your horse against 10 genetic disorders: \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/severe-combined-immunodeficiency-scid\"\u003eSCID\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/lavander-foal-syndrome-lfs-qpcr\"\u003eLFS\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/cerebellar-abiotrophy\"\u003eCA\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/polyssaccharide-storage-myophaty-type-1-pssm1-qpcr\"\u003ePSSM1\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/hyperkalemic-periodic-paralysis-hypp\"\u003eHYPP\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/glycogen-branching-enzyme-deficiency-gbed\"\u003eGBED\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/hereditary-equine-regional-dermal-asthenia-herda\"\u003eHERDA\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/malignant-hyperthermia-mh\"\u003eMH\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/congenital-myotonia-cm\"\u003eCM\u003c\/a\u003e, \u003ca href=\"https:\/\/equigerminal.myshopify.com\/admin\/themes\/73319874604\/editor#\/products\/warmblood-fragile-foal-syndrome-wffs-qpcr\"\u003eWFFS\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eSample Collection\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Roots:\u003c\/strong\u003e 30 to 40 hair roots.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Sample:\u003c\/strong\u003e 5 mL blood in a K3 EDTA tube.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTurnaround Time\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 to 10 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Test?\u003c\/h2\u003e\n\u003cp\u003eOur Certified DNA Disorder-Free Lines test helps breeders, purchasers, and studbook certifiers ensure that horses are free from genetic disorders. This guarantees healthier horses, informed breeding decisions, and enhanced peace of mind.\u003c\/p\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch2\u003eResults Description\u003c\/h2\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/P1:\u003c\/strong\u003e Positive heterozygous. One mutated allele present. The horse can pass the allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP1\/P1:\u003c\/strong\u003e Positive homozygous. Two mutated alleles present. The horse will pass the allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAdditional Information\u003c\/h2\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease that affects many breeds. The condition is caused by a mutation in the GYS1 gene, leading to an abnormal accumulation of glycogen in the muscles. This can cause symptoms such as muscle tremors, stiffness, reluctance to move, and excessive sweating. Management of PSSM1 includes dietary changes and regular exercise to help mitigate symptoms.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is genetic testing important for horse breeders?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic testing is essential for breeders to make informed breeding decisions and to ensure that their horses do not carry alleles for genetic disorders. This helps in maintaining the health and performance of the breed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by SCID and LFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSCID and LFS are commonly found in Arabian horses and breeds influenced by Arabian bloodlines. Testing is crucial for breeding and purchasing decisions to ensure the health of the horses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow prevalent are genetic disorders in certain horse breeds?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic disorders can have significant frequencies in specific breeds. For example, HERDA is prevalent in Quarter Horses, while WFFS often affects Warmbloods. Regular testing helps in identifying carriers and making informed decisions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do genetic disorders impact horse health?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenetic disorders such as SCID, LFS, PSSM1, HYPP, and others can significantly impact the health, performance, and longevity of horses. Early detection through genetic testing allows for better management and breeding practices to ensure healthier future generations.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eHow it Works\u003c\/h2\u003e\n\u003cp\u003e✨ \u003cstrong\u003ePurchase the Test:\u003c\/strong\u003e Select and buy the DNA test online.\u003c\/p\u003e\n\u003cp\u003e📄 \u003cstrong\u003eReceive Instructions:\u003c\/strong\u003e After payment confirmation, receive instructions for hair root collection and a printable submission form.\u003c\/p\u003e\n\u003cp\u003e✂️ \u003cstrong\u003eCollect Hair Roots:\u003c\/strong\u003e Pluck hair roots, tape them on the submission form, place it in an envelope or sealed plastic bag.\u003c\/p\u003e\n\u003cp\u003e📬 \u003cstrong\u003eSend Samples:\u003c\/strong\u003e Send to our lab by regular mail or express delivery to:\u003c\/p\u003e\n\u003cp\u003eEquigerminal Lab\u003cbr\u003eRua Eduardo Correia, Nº13\u003cbr\u003e3030-504 Coimbra, PORTUGAL\u003c\/p\u003e\n\u003cp\u003e📧 \u003cstrong\u003eReceive Results:\u003c\/strong\u003e Get the result certificate by email. If you need assistance, contact us at support@equigerminal.pt.\u003c\/p\u003e\n\u003cp\u003e♻️ \u003cstrong\u003eNote:\u003c\/strong\u003e No need for a sample collection kit, enhancing sustainability by reducing waste and plastic use.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990970179734,"sku":"","price":299.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/CertifiedDNADisorder-FreeLines.png?v=1721076875"},{"product_id":"malignant-hyperthermia-mh","title":"MH Malignant hyperthermia","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Malignant hyperthermia (MH). This\u003c\/span\u003e test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\"\u003eTurnaround time\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eNegative for MH\u003c\/strong\u003e.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eAbsence of the allele responsible for Malignant Hyperthermia (MH).\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/N\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive heterozygous for MH\u003c\/strong\u003e. Presence of one copy of the allele responsible for MH. The horse is affected with the MH disorder and can pass the MH allele\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eto 50% of their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/\u003c\/strong\u003e -\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive homozygous for MH\u003c\/strong\u003e. Presence of two copies of the allele responsible for MH.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected with the MH disorder and will pass the MH allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMalignant Hyperthermia or MH is a genetic muscle disorder that affects Quarter Horses and related breeds. Horses with the MH mutation may not show any physical signs of the disorder until triggered by exposure to anaesthesia or extreme exercise or stress. Symptoms can include high temperature, increased heart rate, high blood pressure, sweating, acidosis, and muscle rigidity. Symptoms develop rapidly, and if not treated quickly, this condition can be fatal. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMH is inherited as an autosomal dominant trait, so the disorder can be passed on even if only one parent has the defective gene. The mutation can be present along with PSSM and if a horse also has PSSM, the symptoms associated with MH can be more severe. Therefore, testing for both PSSM and MH is recommended for Quarter Horse breeds.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAlthough this condition is rare, testing for MH is recommended in case a horse must undergo anaesthesia. Horses that are known to have the MH mutation can be given medication prior to administering anaesthesia to help reduce the severity of the symptoms.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451615731756,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Hyperthermia_maligna.png?v=1571094693"},{"product_id":"lcorl-projected-height-test","title":"Projected Height test, LCORL\/NCAPG","description":"\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test kit\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test to predict the genetic potential for being a \u003cstrong\u003esmall\u003c\/strong\u003e, \u003cstrong\u003emedium\u003c\/strong\u003e or \u003cstrong\u003etall\u003c\/strong\u003e height horse.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood  - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e5 to 8  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e \u003cspan class=\"s1\"\u003eConfidently predict the expected mature height at withers of a young foal.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003eIdentify horses that are 70% likely to be within the specific height range desired by the owner.\u003c\/li\u003e\n\u003cli\u003eProduce horses of a desired height more consistently.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the (C) allele associated to tall height horses, and presents the results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e \u003cstrong\u003eC\/C\u003c\/strong\u003e – \u003cstrong\u003eTall physical height\u003c\/strong\u003e. This genotype, with two copies of the (C) allele,\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eis associated with large horses, (169+\/-4 cm height at the withers). This genotype can be found in draught horses, Westphalians (31%), Oldenburgs (29%), Hanoverians (28%), Holsteiners (18%) and Pureblood Lusitanos (4%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT\/C\u003c\/strong\u003e – \u003cstrong\u003eMedium physical height\u003c\/strong\u003e. This genotype, with one copy of the (T) allele and another of the (C) allele,\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eis associated with medium-sized horses (164+\/-5 cm height at the withers). This genotype can be found in the Holsteiner (64%), Westphalian (60%), Hanoverian (56%) and Pureblood Lusitano (29%).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT\/T\u003c\/strong\u003e – \u003cstrong\u003eSmall physical height\u003c\/strong\u003e. This genotype, with two copies of the (T) allele, is associated with smaller horses (159 +\/- 4 cm height at the withers) and ponies (\u0026lt;148 cm height at the withers). This genotype can be found in the majority of ponies, Arabs (100%) and Pureblood Lusitanos (67%). \u003cspan class=\"Apple-converted-space\"\u003e                               \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/PHtest_1024x1024.png?v=1573246253\" style=\"float: none;\" width=\"1024x1024\" height=\"1024x1024\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"s1\"\u003eThe development of the skeletal apparatus is regulated by the expression of the gene LCORL.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eRecent studies have identified a variation of a simple nucleotide base (Single Nucleotide Polymorphism) in the promoter of this gene.\u003c\/li\u003e\n\u003cli\u003eThe replacement of a thymine (T) with a cytosine (C) varies the expression of the LCORL gene. This variation in the expression influences the horse’s dimension. Consequently, if the expression of the LCORL gene is diminished the resulting horse has a larger body dimension (bones are longer).\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":30303074287660,"sku":"","price":62.73,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Cx_Projected_Height.png?v=1580503071"},{"product_id":"special-offer-package-pssm1-wffs-30-off","title":"WFFS\/FFS \u0026 PSSM1 - DNA Test bundle","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eDNA Test Bundle: PSSM1 \u0026amp; WFFS\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eDiscover Peace of Mind with Precision Equine Genetics.\u003c\/strong\u003e Our DNA test bundle offers a comprehensive genetic screening for Polysaccharide Storage Myopathy Type 1 (PSSM1) and Warmblood Fragile Foal Syndrome (WFFS), empowering you with essential information for the wellbeing of your equine companion.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTests Included\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 Genetic Test:\u003c\/strong\u003e Uncover the presence of the specific allele at the GYS1 locus responsible for PSSM1, a condition affecting muscle metabolism in horses. Early detection can guide management and care. Learn more about the PSSM1 test \u003ca href=\"https:\/\/equigerminal.shop\/products\/polyssaccharide-storage-myophaty-type-1-pssm1-qpcr\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS Genetic Test:\u003c\/strong\u003e This test identifies the allele at the PLOD1 locus responsible for Warmblood Fragile Foal Syndrome (WFFS). Knowing your horse's genetic status aids in making informed breeding decisions. Further details on the WFFS test can be found \u003ca href=\"https:\/\/equigerminal.shop\/products\/warmblood-fragile-foal-syndrome-wffs-qpcr?_pos=2\u0026amp;_sid=1c7559dd5\u0026amp;_ss=r\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Collection\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e20-30 hair roots. Tape the hair to the\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\"\u003e printable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood in an EDTA tube. Send the tube with the \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" target=\"_blank\" rel=\"noopener\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremium Processing:\u003c\/strong\u003e Results in 2 working days after sample arrival. \u003cmeta charset=\"UTF-8\"\u003e \u003cspan\u003eThis service includes free express delivery. For an additional fee of €35, the laboratory arranges express shipping with package pick-up from your address (available for non-remote regions). For premium processing, please contact the laboratory at \u003c\/span\u003e\u003ca rel=\"noreferrer\" target=\"_new\"\u003esupport@equigerminal.pt\u003c\/a\u003e\u003cspan\u003e for further assistance.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cp\u003eThis genetic test helps breeders identify horses carrying the PSSM1 and WFFS alleles. Informed breeding choices can prevent the birth of affected foals. While PSSM1 affects muscle metabolism, WFFS is a fatal connective tissue disorder. Testing for these conditions is often required by studbooks and is highly recommended during pre-purchase exams to ensure the horse's health and performance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/n:\u003c\/strong\u003e Negative for PSSM1. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/P1:\u003c\/strong\u003e Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 P1\/P1:\u003c\/strong\u003e Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/WFFS:\u003c\/strong\u003e Carrier for WFFS. One copy of the mutated allele present. The horse can pass the WFFS allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS WFFS\/WFFS:\u003c\/strong\u003e Positive for WFFS. Two copies of the mutated allele present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease. Such foals will not survive to adulthood and hence will not pass on the allele.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease affecting many breeds, caused by a mutation in the GYS1 gene. Warmblood Fragile Foal Syndrome (WFFS) is a fatal genetic defect of connective tissue, resulting from a mutation in the PLOD1 gene. WFFS is characterized by hyperextensible, fragile skin and mucous membranes, leading to severe lesions and often resulting in euthanasia of affected foals shortly after birth. Both conditions can significantly impact a horse's health and performance, making genetic testing an essential tool for breeders and buyers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\nAblondi, M., et al. (2022). \u003ca href=\"https:\/\/doi.org\/10.1186\/s12711-021-00693-4\" target=\"_blank\"\u003ePerformance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects\u003c\/a\u003e. Genet Sel Evol 54, 4.Rowe, Á., et al. (2021). \u003ca href=\"https:\/\/doi.org\/10.1186\/s13620-021-00206-1\" target=\"_blank\"\u003eWarmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland\u003c\/a\u003e. Ir Vet J 74, 27.Dias, N. M., et al. (2019). \u003ca\u003eDias, N. M., et al. (2019). \u003c\/a\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.tvjl.2019.05.002\" target=\"_blank\"\u003eWarmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil\u003c\/a\u003e. Vet J 248, 101–102.Hoelzle, L., et al. (2020). \u003ca href=\"https:\/\/doi.org\/10.3390\/genes11121518\" target=\"_blank\"\u003eDistribution of the Warmblood Fragile Foal Syndrome Type 1 Mutation (PLOD1 c.2032G\u0026gt;A) in Different Horse Breeds from Europe and the United States\u003c\/a\u003e. Genes 11(12), 1518.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\u003c\/p\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by PSSM1 and WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. WFFS primarily affects Warmbloods but has also been detected in breeds like Thoroughbreds, Knabstruppers, Haflingers, and American Sport Ponies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow are PSSM1 and WFFS inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 is inherited in an autosomal dominant manner, meaning horses with one (n\/P1) or two (P1\/P1) copies of the mutated gene can develop the disease. WFFS is inherited as an autosomal recessive trait, requiring two copies of the mutated gene (WFFS\/WFFS) for the disease to manifest. Affected foals with two copies of the WFFS mutation will not survive to adulthood and must be euthanized shortly after birth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can PSSM1 and WFFS be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 management includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. WFFS, however, is a lethal condition with no cure, emphasizing the importance of genetic testing to inform breeding decisions and avoid producing affected foals.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990960906390,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/FFSPSSM1.png?v=1711469296"},{"product_id":"base-colour-testing-a-and-e-loci","title":"Base colour test - A and E loci","description":"\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003eBuy a Base colour test and find out if your horse's base colour is Black, Bay or Chestnut. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cspan style=\"color: #000000;\"\u003eResults within 24 h are available.\u003c\/span\u003e\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Agouti and Extension \u003cem\u003eloci\u003c\/em\u003e that controls distribution of Black and Red pigment throughout the coat.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40  hair roots \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStandard processing\u003c\/b\u003e - Results in 3-5 working days after sample arrival at the laboratory. Clients organize and support the costs of sending the samples to the laboratory.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePREMIUM processing\u003c\/b\u003e - Results in 1 day after sample arrival. Includes free express delivery** . The laboratory organizes Express shipping with pick-up of the package at the client's address and delivery at the laboratory.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003e** PREMIUM SERVICES INCLUDE AN EXPRESS SHIPPING DELIVERY FOR EUROPEAN COUNTRIES FROM NON-REMOTE REGIONS.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"https:\/\/www.tnt.com\/dam\/tnt_express_media\/global_media_library\/New_Site_Structure\/Home_Page\/HelpCentre\/Postcodes.pdf\"\u003eCheck here to know if you are in a remote European region.\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFor remote\/outreach regions EXTRA fees are applied.\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg style=\"float: none;\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003eHorses have only three base colours: Bay, Black or Chestnut\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThese different colours are controlled by 2 \u003cem\u003eloci\u003c\/em\u003e, the \u003cstrong\u003e\u003cb\u003eExtension\u003c\/b\u003e\u003c\/strong\u003e  (Red\/Black) and \u003cstrong\u003eAgouti\u003c\/strong\u003e\u003cem\u003e.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003e\u003cb\u003eExtension\u003c\/b\u003e\u003c\/strong\u003e \u003cem\u003elocus\u003c\/em\u003e controls the production of black or red pigment throughout the coat. The allele for black color (E) is dominant over the red allele (e), so a horse only needs one copy of the black allele to appear black-based. But if the horse has two alleles (e\/e) he will appear \u003cspan style=\"text-decoration: underline;\"\u003eChestnut\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe \u003cstrong\u003e\u003cb\u003eAgouti\u003c\/b\u003e\u003c\/strong\u003e \u003cem\u003elocus\u003c\/em\u003e can then modify black pigment by pushing it the horse's points, creating a\u003cspan style=\"text-decoration: underline;\"\u003e Bay.\u003c\/span\u003e The Agouti A allele is dominant, so a black pigmented horse only needs one copy (heterozygous) of the A allele to appear \u003cspan style=\"text-decoration: underline;\"\u003eBay\u003c\/span\u003e. The Agouti (a) allelle is recessive, thus, a horse needs two copies (homozygous) of the recessive allele (a) at the Agouti \u003cem\u003elocus\u003c\/em\u003e to appear \u003cspan style=\"text-decoration: underline;\"\u003eBlack\u003c\/span\u003e.\u003c\/p\u003e\n\u003cp\u003eAgouti has no effect on red pigment, but the red allele (e) is dominant over the (a) allele. This means a Chestnut horse (e\/e) can carry one or two copies of the Agouti recessive (a) allele and will look no different from chestnut horses with  Agouti dominant alleles (e\/e a\/a, e\/e A\/a,  e\/e A\/A).\u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eBase Colour\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eExtension\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eAgouti\u003c\/b\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eBay\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eE\/E or E\/e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eA\/A or A\/a\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eBlack\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eE\/E or E\/e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003ea\/a\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eRed\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003ee\/e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"197\"\u003e\n\u003cp\u003eA\/A, A\/a or a\/a\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eRieder, S., Taourit, S., Mariat, D., Langlois, B., \u0026amp; Guérin, G. (2001). Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus). Mammalian genome : official journal of the International Mammalian Genome Society, 12(6), 450–455. https:\/\/doi.org\/10.1007\/s003350020017 \u003c\/p\u003e\n\u003cbr\u003eMarklund, L., Moller, M. J., Sandberg, K., \u0026amp; Andersson, L. (1996). A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses. Mammalian genome : official journal of the International Mammalian Genome Society, 7(12), 895–899. https:\/\/doi.org\/10.1007\/s003359900264","brand":"Equigerminal","offers":[{"title":"Standard - Results in 3-5 d","offer_id":41992494612630,"sku":null,"price":61.5,"currency_code":"EUR","in_stock":true},{"title":"PREMIUM - Results in 1 d \u0026 free Express delivery","offer_id":41992494645398,"sku":null,"price":95.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Basecolourtest.png?v=1665065762"},{"product_id":"equisample-express-kit","title":"EquiSample Express Kit","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003cmeta content=\"Purchase the EquiSample Express Kit for various tests, including genetic, parasitic, nutritional, and veterinary tests. Receive a home kit with all materials and prepaid express return shipping.\" name=\"description\"\u003e \u003cmeta content=\"EquiSample Express Kit, sample collection kit, genetic tests, parasitic tests, nutritional tests, veterinary tests, saliva swabs, stool samples, mane samples, Equigerminal\" name=\"keywords\"\u003e \u003cmeta content=\"Equigerminal\" name=\"author\"\u003e \u003cmeta content=\"EquiSample Express Kit | Equigerminal\" property=\"og:title\"\u003e \u003cmeta content=\"Purchase the EquiSample Express Kit for various tests, including genetic, parasitic, nutritional, and veterinary tests. Receive a home kit with all materials and prepaid express return shipping.\" property=\"og:description\"\u003e \u003cmeta content=\"product\" property=\"og:type\"\u003e \u003cmeta content=\"https:\/\/equigerminal.shop\/product\/equisample-express-kit\" property=\"og:url\"\u003e \u003cmeta content=\"https:\/\/equigerminal.shop\/images\/express-kit.jpg\" property=\"og:image\"\u003e \u003cmeta content=\"Equigerminal\" property=\"og:site_name\"\u003e \u003cmeta content=\"summary_large_image\" property=\"twitter:card\"\u003e \u003cmeta content=\"EquiSample Express Kit | Equigerminal\" property=\"twitter:title\"\u003e \u003cmeta content=\"Purchase the EquiSample Express Kit for various tests, including genetic, parasitic, nutritional, and veterinary tests. Receive a home kit with all materials and prepaid express return shipping.\" property=\"twitter:description\"\u003e \u003cmeta content=\"https:\/\/equigerminal.shop\/images\/express-kit.jpg\" property=\"twitter:image\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {\n            font-family: Arial, sans-serif;\n            line-height: 1.6;\n            background-color: #f9f9f9;\n            color: #333;\n            margin: 0;\n            padding: 0;\n        }\n        .content {\n            padding: 20px;\n        }\n        h2 {\n            color: #DA556A; \/* Red color for the Strangles collection *\/\n            margin-top: 20px;\n        }\n        ul {\n            list-style-type: none;\n            padding-left: 0;\n            margin: 0;\n        }\n        li {\n            padding: 8px;\n            border-bottom: 1px solid #ddd;\n        }\n        .highlight {\n            background-color: #FDECEA; \/* Light red background for highlight *\/\n            padding: 10px;\n            border-left: 4px solid #DA556A; \/* Red left border *\/\n            margin-bottom: 20px;\n        }\n        .toggle-btn {\n            display: inline-block;\n            margin-top: 10px;\n            padding: 10px 20px;\n            background-color: #DA556A; \/* Red background for buttons *\/\n            color: white;\n            text-align: center;\n            text-decoration: none;\n            border-radius: 5px;\n            cursor: pointer;\n        }\n        .toggle-btn:hover {\n            background-color: #C23D51; \/* Darker red for hover *\/\n        }\n        .expandable {\n            display: none; \/* Hide content until button is clicked *\/\n            margin-top: 20px;\n        }\n        .highlight ul {\n            list-style-type: disc;\n            padding-left: 20px;\n        }\n    \u003c\/style\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eAbout the EquiSample Express Kit\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTailored to Specific Test:\u003c\/strong\u003e The EquiSample Express Kit is customized based on the test purchased from Equigerminal.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplete Kit:\u003c\/strong\u003e Includes all necessary materials and prepaid express return shipping.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Use:\u003c\/strong\u003e Suitable for both home tests and veterinary tests.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample Collection:\u003c\/strong\u003e Collect samples yourself or consult a vet if a prescription is needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandardized Results:\u003c\/strong\u003e Ensures consistency without hassle, freeing up your vet to focus on care.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdeal for International Shipments:\u003c\/strong\u003e Perfect for tests requiring rapid sample delivery, like hormone assays, where sample stabilizers can't be used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e🛒 \u003cstrong\u003ePurchase the Test and Kit:\u003c\/strong\u003e Select and buy the test and kit online.\u003c\/li\u003e\n\u003cli\u003e📦 \u003cstrong\u003eReceive the Kit:\u003c\/strong\u003e You will receive the kit at home with all necessary materials and prepaid express return shipping.\u003c\/li\u003e\n\u003cli\u003e📄 \u003cstrong\u003eDownload the Submission Form:\u003c\/strong\u003e If you choose not to purchase the EquiSample Kit, download the submission form \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/EGSubmissionForm.pdf?v=1721478282\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e📮 \u003cstrong\u003eReturn the Sample:\u003c\/strong\u003e Place the collected sample in the prepaid express envelope and use the door pickup service. If you did not purchase the kit, you are responsible for shipping the sample to our lab via regular mail.\u003c\/li\u003e\n\u003cli\u003e📄 \u003cstrong\u003eReceive Results:\u003c\/strong\u003e Get the result certificate by email. If you need assistance, contact us at support@equigerminal.pt.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTypes of Tests\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHome Tests:\u003c\/strong\u003e For healthy animals, these tests do not require invasive samples or veterinary prescriptions. Examples include:\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003eGenetic Tests: Saliva\/swabs, mane root samples, and other non-invasive samples\u003c\/li\u003e\n\u003cli\u003eParasitic Tests: Stool samples\u003c\/li\u003e\n\u003cli\u003eNutritional Tests: Non-invasive samples\u003c\/li\u003e\n\u003cli\u003eFood Tests: Analysis of various food samples\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Tests:\u003c\/strong\u003e For infectious diseases or sick animals, these tests require invasive sample collection (e.g., blood) and must be prescribed by a veterinarian. Veterinarians can also request specific kits and materials.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHome Test Kits Include\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGenetic Tests:\u003c\/strong\u003e Includes a sealed card or envelope for mane samples, saliva\/swabs, gloves, a sealed bag, and submission forms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eParasitic Tests:\u003c\/strong\u003e Includes tools for stool sample collection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNutritional and Food Tests:\u003c\/strong\u003e Includes the necessary materials for collecting non-invasive samples and submission forms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVeterinary Test Kits Include\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFor infectious disease tests, includes materials for invasive sample collection (e.g., blood) and submission forms.\u003c\/li\u003e\n\u003cli\u003eVeterinary-specific materials as requested.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePricing and Delivery Time\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePortugal\u003c\/strong\u003e \u0026amp;\u003cstrong\u003e Spain :\u003c\/strong\u003e Delivery in 1 business day\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInternational:\u003c\/strong\u003e Delivery in 1-2 business days (Valid only for Europe in non-remote areas. For other regions, please contact us.)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMultiple Animal Testing\u003c\/h2\u003e\n\u003cp\u003eYou can purchase kits for testing a single animal or multiple animals. The cost of transportation is unitary, meaning you only pay for shipping once, regardless of the number of animals being tested.\u003c\/p\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003ca class=\"toggle-btn\"\u003eView FAQs\u003c\/a\u003e\n\u003cdiv id=\"faq-details\" class=\"expandable\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat is included in the EquiSample Kit?\u003c\/strong\u003e Each kit includes specific materials based on the type of test purchased, such as swabs, sealed tubes, gloves, submission forms, and a prepaid return envelope.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow do I collect a sample?\u003c\/strong\u003e Detailed instructions for sample collection are provided with each kit. For home tests, follow the instructions carefully. For veterinary tests, your veterinarian will handle the sample collection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan I purchase additional collection kits?\u003c\/strong\u003e Yes, you can purchase additional EquiSample Kits with all necessary materials and prepaid return shipping for a hassle-free experience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow do I return the sample?\u003c\/strong\u003e If you purchase the EquiSample Kit, place the collected sample in the provided prepaid envelope and drop it off at your national postal service (for Standard Kit) or use the door pickup service (for Express Kit). If you do not purchase the kit, you are responsible for shipping the sample to our lab via regular mail.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow long does it take to receive the results?\u003c\/strong\u003e The turnaround time for most tests is typically 2 to 5 working days from the receipt of the sample in our laboratory.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWho can I contact for support?\u003c\/strong\u003e If you need assistance, contact our support team at support@equigerminal.pt.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch2\u003eAdditional Information\u003c\/h2\u003e\n\u003ca class=\"toggle-btn\"\u003eView More Info\u003c\/a\u003e\n\u003cdiv id=\"more-info\" class=\"expandable\"\u003e\n\u003cp\u003eFor more detailed information on the EquiSample Kits, including sample collection and submission instructions, please visit our website or contact our support team at support@equigerminal.pt.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\" target=\"_blank\"\u003eVisit our website\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n            function toggleSection(id) {\n                var section = document.getElementById(id);\n                if (section.style.display === 'none' || section.style.display === '') {\n                    section.style.display = 'block';\n                } else {\n                    section.style.display = 'none';\n                }\n            }\n        \u003c\/script\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"1","offer_id":48836450287944,"sku":"","price":40.0,"currency_code":"EUR","in_stock":true},{"title":"2","offer_id":48836450320712,"sku":"","price":50.0,"currency_code":"EUR","in_stock":true},{"title":"3","offer_id":48836450353480,"sku":"","price":60.0,"currency_code":"EUR","in_stock":true},{"title":"4","offer_id":48836450386248,"sku":"","price":70.0,"currency_code":"EUR","in_stock":true},{"title":"5","offer_id":48836450419016,"sku":"","price":80.0,"currency_code":"EUR","in_stock":true},{"title":"6","offer_id":48836450484552,"sku":"","price":90.0,"currency_code":"EUR","in_stock":true},{"title":"7","offer_id":48836450517320,"sku":"","price":100.0,"currency_code":"EUR","in_stock":true},{"title":"8","offer_id":48836450550088,"sku":"","price":120.0,"currency_code":"EUR","in_stock":true},{"title":"9","offer_id":48836450582856,"sku":"","price":130.0,"currency_code":"EUR","in_stock":true},{"title":"10","offer_id":48836450615624,"sku":"","price":140.0,"currency_code":"EUR","in_stock":true}]}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/collections\/DNA.png?v=1677477302","url":"https:\/\/www.equigerminal.org\/tr\/collections\/dna-testing.oembed","provider":"Equigerminal","version":"1.0","type":"link"}