{"title":"Performance \u0026 Wellness","description":"\u003cp\u003eMonitor muscle function, metabolism, cardiovascular health and overall fitness with laboratory profiles developed to support sport horses, active horses and long-term performance management.\u003c\/p\u003e","products":[{"product_id":"high-health-high-performance-horse-profile","title":"High Health High Performance Horse Profile","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003cmeta content=\"Ensure your horse's high health and performance with our comprehensive diagnostic profile. Includes tests for Equine Infectious Anemia Virus (EIAV), Babesia caballi, and Theileria equi. Follow ISO17025 standards.\" name=\"description\"\u003e \u003cmeta content=\"High Health Horse, High Performance Horse, Equine Diagnostic Profile, Equine Infectious Anemia Virus, Coggins Test, Babesia caballi, Theileria equi, ISO17025 standards, Horse Health, Veterinary Diagnostics\" name=\"keywords\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {\n            font-family: Arial, sans-serif;\n            line-height: 1.6;\n            background-color: #f9f9f9;\n            color: #333;\n            margin: 0;\n            padding: 0;\n        }\n        .content {\n            padding: 20px;\n        }\n        h2 {\n            color: #DA556A;\n            margin-top: 20px;\n        }\n        ul {\n            list-style-type: none;\n            padding-left: 0;\n            margin: 0;\n        }\n        li {\n            padding: 8px;\n            border-bottom: 1px solid #ddd;\n        }\n        .highlight {\n            background-color: #FDECEA;\n            padding: 10px;\n            border-left: 4px solid #DA556A;\n            margin-bottom: 20px;\n        }\n        .toggle-btn {\n            display: inline-block;\n            margin-top: 10px;\n            padding: 10px 20px;\n            background-color: #DA556A;\n            color: white;\n            text-align: center;\n            text-decoration: none;\n            border-radius: 5px;\n            cursor: pointer;\n        }\n        .toggle-btn:hover {\n            background-color: #C23D51;\n        }\n        .expandable {\n            display: none;\n            margin-top: 20px;\n        }\n    \u003c\/style\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cp\u003eEnsure your horse's high health and performance with our comprehensive diagnostic profile. This profile includes three tests that follow ISO17025 standards, ensuring the highest level of accuracy and reliability.\u003c\/p\u003e\n\u003ch2\u003eTests Included\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEquine Infectious Anemia Virus (EIAV), AGID - Coggins Test\u003c\/li\u003e\n\u003cli\u003eBabesia caballi, C-ELISA\u003c\/li\u003e\n\u003cli\u003eTheileria equi, C-ELISA\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTest Details\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathogens Detected:\u003c\/strong\u003e EIAV, Babesia caballi, and Theileria equi.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSample Requirements:\u003c\/strong\u003e 5 mL of blood, serum, or plasma collected in a dry or EDTA tube.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTurnaround Time:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003eStandard Processing: Results within 2-5 working days after sample receipt.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Choose This Profile?\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003eThis diagnostic profile is essential for maintaining high health and performance in horses. It includes comprehensive testing for Equine Infectious Anemia Virus, Babesia caballi, and Theileria equi, ensuring early detection and management of these critical health conditions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('how-it-works')\"\u003eHow It Works\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"how-it-works\"\u003e\n\u003cul\u003e\n\u003cli\u003e🛒 \u003cstrong\u003ePurchase the Test:\u003c\/strong\u003e Select and buy the test online.\u003c\/li\u003e\n\u003cli\u003e📧 \u003cstrong\u003eReceive Instructions:\u003c\/strong\u003e After payment confirmation, receive instructions for sample collection.\u003c\/li\u003e\n\u003cli\u003e✨ \u003cstrong\u003eSample Collection:\u003c\/strong\u003e Your veterinarian collects the sample.\u003c\/li\u003e\n\u003cli\u003e📄 \u003cstrong\u003eDownload Submission Form:\u003c\/strong\u003e Download the printable submission form \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/Pathogen_form.pdf?v=1719770781\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e📮 \u003cstrong\u003eSend Samples:\u003c\/strong\u003e Send to our lab by regular mail or express delivery to:\u003cbr\u003eEquigerminal Lab\u003cbr\u003eRua Eduardo Correia, Nº13\u003cbr\u003e3030-507 Coimbra, PORTUGAL\u003c\/li\u003e\n\u003cli\u003e📄 \u003cstrong\u003eReceive Results:\u003c\/strong\u003e Get the result certificate by email. If you need assistance, contact us at support@equigerminal.pt.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch2\u003eMore Info\u003c\/h2\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('more-info')\"\u003eView More Info\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"more-info\"\u003e\n\u003cp\u003eFor more detailed information on this diagnostic profile, including sample collection and submission instructions, please visit our website or contact our support team.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/equine-piroplasmosis-diagnosis\" target=\"_blank\"\u003eVisit our detailed diagnosis page\u003c\/a\u003e for more information.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-details')\"\u003eView FAQs\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-details\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow do the tests work?\u003c\/strong\u003e The profile includes the AGID (Coggins) test for EIAV, and cELISA tests for Babesia caballi and Theileria equi, following ISO17025 standards for high accuracy and reliability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat types of samples are required for the tests?\u003c\/strong\u003e\n\u003cp\u003e5 mL of blood, serum, or plasma collected in a dry or EDTA tube.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow long does it take to get the test results?\u003c\/strong\u003e The turnaround time is 2-5 working days after the sample is received in the laboratory.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat should be done if a horse tests positive?\u003c\/strong\u003e Horses that test positive should be isolated to prevent the spread of the disease. Follow biosecurity measures and consult with a veterinarian for appropriate treatment and management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow can these diseases be prevented?\u003c\/strong\u003e Prevention involves regular testing, controlling tick exposure, using repellents, acaricides, and regular inspections, and following biosecurity measures.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41991060160662,"sku":"","price":100.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/HighHealth_HighPerformanceHorseProfile_6bd41a7b-925e-412d-85ca-020d4fd3a375.png?v=1719781155"},{"product_id":"polyssaccharide-storage-myophaty-type-1-pssm1-qpcr","title":"PSSM1 Polysaccharide Storage Myopathy Type 1","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eAbout the Test\u003c\/h2\u003e\n\u003cp class=\"highlight\"\u003eThe PSSM1 DNA test verifies the presence of the affected allele at the GYS1 locus responsible for Polysaccharide Storage Myopathy Type 1 (PSSM1).\u003c\/p\u003e\n\u003ch2\u003eSample Collection\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Roots:\u003c\/strong\u003e 20 to 30 hair roots. Pull the hair and tape it onto the \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Sample:\u003c\/strong\u003e 5 mL blood in a K3 EDTA tube. Collect the blood and send the tube together with the \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" target=\"_blank\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTurnaround Time\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhy Test?\u003c\/h2\u003e\n\u003cp\u003eThis genetic test helps breeders identify horses carrying the PSSM allele. Informed breeding choices can prevent the birth of affected foals. While PSSM cannot be cured, muscle function can be managed with dietary changes and exercise routines.\u003c\/p\u003e\n\u003cp\u003eThe PSSM1 test is required by many studbooks and is highly recommended when considering the purchase of a horse. Testing for PSSM1 as part of the pre-purchase examination can ensure that you are making an informed decision, as the condition can impact the horse's performance and overall health.\u003c\/p\u003e\n\u003ca class=\"toggle-btn\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch2\u003eResults Description\u003c\/h2\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/n:\u003c\/strong\u003e Negative for PSSM1. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003en\/P1:\u003c\/strong\u003e Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP1\/P1:\u003c\/strong\u003e Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAdditional Information\u003c\/h2\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease that affects many breeds. The condition is caused by a mutation in the GYS1 gene, leading to an abnormal accumulation of glycogen in the muscles. This can cause symptoms such as muscle tremors, stiffness, reluctance to move, and excessive sweating. Management of PSSM1 includes dietary changes and regular exercise to help mitigate symptoms.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\"\u003eCheck our FAQs for more information\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch2\u003eFAQs\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by PSSM1?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. The prevalence of the mutation varies by breed, with some breeds having a higher incidence of the condition.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is PSSM1 inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 is inherited in an autosomal dominant manner, meaning that horses with one (n\/P1) or two (P1\/P1) copies of the mutated gene can develop the disease. Horses with two copies generally show more severe symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can PSSM1 be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eManagement includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. These measures can help prevent the onset of symptoms or reduce their severity.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Standard. Results in 5 days","offer_id":47813083988296,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/PSSM1test.png?v=1716890764"},{"product_id":"hyperkalemic-periodic-paralysis-hypp","title":"HYPP Hyperkalemic Periodic Paralysis","description":"\u003cp\u003e\u003cspan style=\"font-size: 1.4em;\" class=\"s1\"\u003eDNA test for the Hyperkalemic Periodic Paralysis Disease (HYPP). \u003c\/span\u003e\u003cspan style=\"font-size: 1.4em;\" class=\"s1\"\u003eThis DNA test verifies the presence of the recessive HYPP gene.\u003c\/span\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\" color=\"#c739d2\"\u003eSample \u003cspan style=\"caret-color: #c739d2;\"\u003erequirements\u003c\/span\u003e \u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 hair roots \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL of blood in K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eTurnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg style=\"float: none;\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" alt=\"\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #e8b80d;\"\u003e\u003cstrong\u003eWhy test?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003eThis genetic test helps breeders to identify horses that carrying the HYPP recessive gene. Informed choices can be made for breeding selections, and prevent the born of affected foals. \u003c\/span\u003eAll offspring of Impressive should be tested for HYPP.\u003c\/li\u003e\n\u003cli\u003eBecause HYPP is dominant disorder, the effects of it can also be transposed to other breeds of horses when intermixing occurs. This test is important in preserving the inherited health of all horses.\u003c\/li\u003e\n\u003cli\u003eHorses with suspicious symptoms of the disease should also be tested.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the recessive HYPP gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eN\/\u003c\/b\u003e –  \u003cstrong\u003eNormal - \u003c\/strong\u003eAbsence of the allele responsible for HYPP.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eN\/H\u003c\/strong\u003e – \u003cstrong\u003eAffected - Positive heterozygous for HYPP.\u003c\/strong\u003e Presence of one copy of the allele responsible for HYPP. The horse is affected with the HYPP disorder and there is a 50% chance this horse will pass a HYPP allele to its offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eH\/\u003c\/strong\u003e \u003cstrong\u003e– Affected- Positive homozygous for HYPP\u003c\/strong\u003e. Presence of two copies of the allele responsible for HYPP. The horse is affected with the HYPP disorder and there is a 100% chance this horse will pass a HYPP allele to its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHyperkalemic Periodic paralysis (HYPP) is an inherited disease of the muscle, which is caused by an inherited genetic mutation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eA point mutation in DNA exists in the sodium channel gene, which codes for an abnormal channel to be expressed in skeletal muscle. This mutation is passed on to offspring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSodium channels are “pores” in the muscle cell membrane which control contraction of the muscle fibers. When the defective sodium channel gene is present, the channel becomes “leaky” and makes the muscle overly excitable and contract involuntarily.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe channel become “leaky” when potassium levels fluctuate in the blood. This may occur with fasting followed by consumption of a high potassium feed such as alfalfa. Hyperkalemia, which is an excessive amount of potassium in the blood, causes the muscles in the horse to contract more readily than normal. This makes the horse susceptible to sporadic episodes of muscle tremors or paralysis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eSeverity of attacks varies from unnoticeable to collapse or sudden death. The cause of death is usually respiratory failure and\/or cardiac arrest.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThis genetic defect has been identified in offspring of the American Quarter Horse sire, Impressive. To date, confirmed cases of HYPP have been restricted to descendants of this horse. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eHYPP is a dominant disorder meaning both homozygous positive (HH) and heterozygous (nH) horses will be affected. Only homozygous negative (nn) horses are not affected by HYPP.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451379081260,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/HYPP.png?v=1571094950"},{"product_id":"polysaccharide-storage-myophaty-type-2-pssm2","title":"MIM (PSSM2) DNA Test - 6 variant panel","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eMIM (PSSM2) DNA Test\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eEnsure the Health and Performance of Your Horses with Accurate MIM Testing.\u003c\/strong\u003e Our DNA test identifies the presence of genetic variants associated with Muscle Integrity Myopathy (MIM), formerly known as PSSM2, which affects muscle function and structure.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Requirements\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e30 to 40 hair roots - envelope\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003eup to 15 working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test identifies six genetic variants that predispose horses to developing symptoms of Muscle Integrity Myopathy:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eP2:\u003c\/strong\u003e Myotilinopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP3:\u003c\/strong\u003e Filaminopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP4:\u003c\/strong\u003e Myozenin-3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP8:\u003c\/strong\u003e PYROXD1-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePx:\u003c\/strong\u003e CACNA2D3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eK1:\u003c\/strong\u003e COL6A3-Myopathy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eGenetic Inheritance\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eMuscle Integrity Myopathy (MIM) is caused by a hereditary predisposition involving multiple genetic variants. These variants disrupt the structure and function of muscle fibers, leading to symptoms such as muscle stiffness, unexplained lameness, and difficulty building muscle.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eClinical Signs and Affected Breeds\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eSymptoms of MIM can vary widely among horses and include unexplained lameness, muscle stiffness, difficulty with gait changes, reluctance to move, muscle atrophy, and behavioral changes. Almost any breed can be affected, with common occurrences in breeds like Quarter Horses, Warmbloods, and Thoroughbreds.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cp\u003eTesting for MIM is crucial for breeders and owners to make informed decisions. By identifying carriers of the genetic variants, breeding choices can be optimized to prevent the spread of these disorders. Additionally, knowing a horse's genetic status can help manage and mitigate symptoms through tailored exercise and feeding protocols.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv id=\"learn-more-content\" class=\"expandable\"\u003e\n\u003ch3 class=\"section-title\"\u003eDetailed Results Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will indicate the presence of the following genetic variants:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eP2:\u003c\/strong\u003e Myotilinopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP3:\u003c\/strong\u003e Filaminopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP4:\u003c\/strong\u003e Myozenin-3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eP8:\u003c\/strong\u003e PYROXD1-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePx:\u003c\/strong\u003e CACNA2D3-Myopathy\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eK1:\u003c\/strong\u003e COL6A3-Myopathy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eMuscle Integrity Myopathy (MIM) is a genetic disorder that disrupts muscle function and structure, leading to various clinical signs. While it is not possible to cure genetic disorders, optimized management through diet and exercise can help mitigate symptoms, allowing horses to lead normal lives.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\nGeneratio. \u003ca href=\"https:\/\/www.generatio.de\/mim-pssm2\" target=\"_blank\"\u003eMuscle Integrity Myopathy in Horses\u003c\/a\u003eEquiSeq. \u003ca href=\"https:\/\/www.equiseq.com\/learn_pssm2\" target=\"_blank\"\u003ePolysaccharide Storage Myopathy type 2 (PSSM2)\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\u003c\/p\u003e\n\u003cdiv id=\"faq-content\" class=\"expandable\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by MIM?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAlmost any breed can be affected by MIM, with common occurrences in breeds like Quarter Horses, Warmbloods, and Thoroughbreds.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is MIM inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMIM is caused by multiple genetic variants that disrupt muscle structure and function. These variants are inherited and can predispose horses to developing symptoms of exertional myopathy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can MIM be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile genetic disorders cannot be cured, their symptoms can often be managed through optimized feeding and exercise protocols. Identifying genetic variants through testing allows for tailored management strategies to mitigate symptoms.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Generatio","offers":[{"title":"Default Title","offer_id":29451457724460,"sku":"","price":357.32,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/MIMPSSM2.png?v=1716904823"},{"product_id":"malignant-hyperthermia-mh","title":"MH Malignant hyperthermia","description":"\u003cdiv\u003e\u003cspan style=\"color: #c739d2;\"\u003e\u003cstrong\u003eDNA test\u003c\/strong\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eDNA test for the Malignant hyperthermia (MH). This\u003c\/span\u003e test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong style=\"color: #c739d2;\"\u003e\u003cstrong\u003eSample\u003c\/strong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cstrong\u003e30 to 40 - hair roots - envelope\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eor\u003c\/span\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e5 mL - blood - K3 EDTA tube\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: #c739d2;\"\u003eTurnaround time\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e2 to 5  working days\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: right;\"\u003e\u003cimg alt=\"\" src=\"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/F_ISAG_MEMBER_small.jpg?v=1563820312\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #00afab;\"\u003e\u003cstrong\u003eResults description\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eThe DNA test verifies the presence of the dominant MH gene and presents results as one of the following:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eN\/\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eNegative for MH\u003c\/strong\u003e.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eAbsence of the allele responsible for Malignant Hyperthermia (MH).\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/N\u003c\/strong\u003e - \u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive heterozygous for MH\u003c\/strong\u003e. Presence of one copy of the allele responsible for MH. The horse is affected with the MH disorder and can pass the MH allele\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eto 50% of their progeny when bred.\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"s1\"\u003e\u003cspan class=\"s1\"\u003e\u003cstrong\u003eMH\/\u003c\/strong\u003e -\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cstrong\u003eAffected - Positive homozygous for MH\u003c\/strong\u003e. Presence of two copies of the allele responsible for MH.\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003eThe horse is affected with the MH disorder and will pass the MH allele to 100% of its offspring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional information\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMalignant Hyperthermia or MH is a genetic muscle disorder that affects Quarter Horses and related breeds. Horses with the MH mutation may not show any physical signs of the disorder until triggered by exposure to anaesthesia or extreme exercise or stress. Symptoms can include high temperature, increased heart rate, high blood pressure, sweating, acidosis, and muscle rigidity. Symptoms develop rapidly, and if not treated quickly, this condition can be fatal. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eMH is inherited as an autosomal dominant trait, so the disorder can be passed on even if only one parent has the defective gene. The mutation can be present along with PSSM and if a horse also has PSSM, the symptoms associated with MH can be more severe. Therefore, testing for both PSSM and MH is recommended for Quarter Horse breeds.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eAlthough this condition is rare, testing for MH is recommended in case a horse must undergo anaesthesia. Horses that are known to have the MH mutation can be given medication prior to administering anaesthesia to help reduce the severity of the symptoms.\u003c\/span\u003e\u003c\/p\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":29451615731756,"sku":"","price":43.05,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Hyperthermia_maligna.png?v=1571094693"},{"product_id":"copper","title":"Copper","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eParameter\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eCopper\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan style=\"color: #c739d2;\" data-mce-style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e Sample\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e5 mL - blood -\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eserum tube \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan style=\"color: #c739d2;\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e Turnaround time\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e2 to 5 working days\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":40861959422102,"sku":"","price":11.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/products\/Copper.png?v=1632931823"},{"product_id":"special-offer-package-pssm1-wffs-30-off","title":"WFFS\/FFS \u0026 PSSM1 - DNA Test bundle","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cmeta content=\"width=device-width, initial-scale=1.0\" name=\"viewport\"\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n        body {font-family: Arial, sans-serif; line-height: 1.6; background-color: #f9f9f9; color: #333; margin: 0; padding: 0;}\n        .content {padding: 20px;}\n        h2 {color: #E11BE9; margin-top: 20px;}\n        h3 {color: #119EC2; margin-top: 20px;}\n        ul {list-style-type: square; padding-left: 20px;}\n        .toggle-btn {display: inline-block; margin-top: 10px; padding: 10px 20px; background-color: #119EC2; color: white; text-align: center; text-decoration: none; border-radius: 5px; cursor: pointer;}\n        .toggle-btn:hover {background-color: #0b7a96;}\n        .highlight {background-color: #f3e5f5; padding: 10px; border-left: 4px solid #E11BE9; margin-bottom: 20px;}\n        .expandable {display: none; margin-top: 20px;}\n        .shaded-box {background-color: #f9f9f9; border: 1px solid #ddd; padding: 15px; border-radius: 5px; box-shadow: 0 2px 4px rgba(0,0,0,0.1); margin-bottom: 20px;}\n        .section-title {color: #E11BE9; padding: 10px; margin-bottom: 10px; font-size: 1.2em;}\n    \u003c\/style\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv class=\"content\"\u003e\n\u003ch2\u003eDNA Test Bundle: PSSM1 \u0026amp; WFFS\u003c\/h2\u003e\n\u003cdiv class=\"highlight\"\u003e\n\u003cp\u003e\u003cstrong\u003eDiscover Peace of Mind with Precision Equine Genetics.\u003c\/strong\u003e Our DNA test bundle offers a comprehensive genetic screening for Polysaccharide Storage Myopathy Type 1 (PSSM1) and Warmblood Fragile Foal Syndrome (WFFS), empowering you with essential information for the wellbeing of your equine companion.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTests Included\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 Genetic Test:\u003c\/strong\u003e Uncover the presence of the specific allele at the GYS1 locus responsible for PSSM1, a condition affecting muscle metabolism in horses. Early detection can guide management and care. Learn more about the PSSM1 test \u003ca href=\"https:\/\/equigerminal.shop\/products\/polyssaccharide-storage-myophaty-type-1-pssm1-qpcr\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS Genetic Test:\u003c\/strong\u003e This test identifies the allele at the PLOD1 locus responsible for Warmblood Fragile Foal Syndrome (WFFS). Knowing your horse's genetic status aids in making informed breeding decisions. Further details on the WFFS test can be found \u003ca href=\"https:\/\/equigerminal.shop\/products\/warmblood-fragile-foal-syndrome-wffs-qpcr?_pos=2\u0026amp;_sid=1c7559dd5\u0026amp;_ss=r\" target=\"_blank\"\u003ehere\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eSample Collection\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e20-30 hair roots. Tape the hair to the\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\"\u003e printable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eAlternatively, 5 mL blood in an EDTA tube. Send the tube with the \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/DNA_FormNewAddress.pdf?v=1724086853\" target=\"_blank\" rel=\"noopener\"\u003eprintable sample submission form.\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eTurnaround Time\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStandard Processing:\u003c\/strong\u003e Results in 5 working days after sample arrival at the laboratory. Clients organize and cover the costs of sending the samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremium Processing:\u003c\/strong\u003e Results in 2 working days after sample arrival. \u003cmeta charset=\"UTF-8\"\u003e \u003cspan\u003eThis service includes free express delivery. For an additional fee of €35, the laboratory arranges express shipping with package pick-up from your address (available for non-remote regions). For premium processing, please contact the laboratory at \u003c\/span\u003e\u003ca rel=\"noreferrer\" target=\"_new\"\u003esupport@equigerminal.pt\u003c\/a\u003e\u003cspan\u003e for further assistance.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3\u003eWhy Test?\u003c\/h3\u003e\n\u003cdiv class=\"shaded-box\"\u003e\n\u003cp\u003eThis genetic test helps breeders identify horses carrying the PSSM1 and WFFS alleles. Informed breeding choices can prevent the birth of affected foals. While PSSM1 affects muscle metabolism, WFFS is a fatal connective tissue disorder. Testing for these conditions is often required by studbooks and is highly recommended during pre-purchase exams to ensure the horse's health and performance.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ca class=\"toggle-btn\" onclick=\"toggleSection('learn-more-content')\"\u003eLearn More\u003c\/a\u003e\n\u003cdiv class=\"expandable\" id=\"learn-more-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eResults Description\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003eThe DNA test results will be one of the following:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/n:\u003c\/strong\u003e Negative for PSSM1. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 n\/P1:\u003c\/strong\u003e Positive heterozygous for PSSM1. One mutated allele present. The horse can pass the PSSM1 allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePSSM1 P1\/P1:\u003c\/strong\u003e Positive homozygous for PSSM1. Two mutated alleles present. The horse will pass the PSSM1 allele to 100% of its offspring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/n:\u003c\/strong\u003e Negative for WFFS. No affected allele present.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS n\/WFFS:\u003c\/strong\u003e Carrier for WFFS. One copy of the mutated allele present. The horse can pass the WFFS allele to 50% of its progeny.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWFFS WFFS\/WFFS:\u003c\/strong\u003e Positive for WFFS. Two copies of the mutated allele present. The foal will exhibit severe clinical signs and must be euthanized shortly after birth due to the untreatable nature of the disease. Such foals will not survive to adulthood and hence will not pass on the allele.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eAdditional Information\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003ePolysaccharide Storage Myopathy (PSSM1) is a hereditary muscle disease affecting many breeds, caused by a mutation in the GYS1 gene. Warmblood Fragile Foal Syndrome (WFFS) is a fatal genetic defect of connective tissue, resulting from a mutation in the PLOD1 gene. WFFS is characterized by hyperextensible, fragile skin and mucous membranes, leading to severe lesions and often resulting in euthanasia of affected foals shortly after birth. Both conditions can significantly impact a horse's health and performance, making genetic testing an essential tool for breeders and buyers.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch3 class=\"section-title\"\u003eReferences\u003c\/h3\u003e\nAblondi, M., et al. (2022). \u003ca href=\"https:\/\/doi.org\/10.1186\/s12711-021-00693-4\" target=\"_blank\"\u003ePerformance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects\u003c\/a\u003e. Genet Sel Evol 54, 4.Rowe, Á., et al. (2021). \u003ca href=\"https:\/\/doi.org\/10.1186\/s13620-021-00206-1\" target=\"_blank\"\u003eWarmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland\u003c\/a\u003e. Ir Vet J 74, 27.Dias, N. M., et al. (2019). \u003ca\u003eDias, N. M., et al. (2019). \u003c\/a\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.tvjl.2019.05.002\" target=\"_blank\"\u003eWarmblood Fragile Foal Syndrome causative single nucleotide polymorphism frequency in Warmblood horses in Brazil\u003c\/a\u003e. Vet J 248, 101–102.Hoelzle, L., et al. (2020). \u003ca href=\"https:\/\/doi.org\/10.3390\/genes11121518\" target=\"_blank\"\u003eDistribution of the Warmblood Fragile Foal Syndrome Type 1 Mutation (PLOD1 c.2032G\u0026gt;A) in Different Horse Breeds from Europe and the United States\u003c\/a\u003e. Genes 11(12), 1518.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003ca class=\"toggle-btn\" onclick=\"toggleSection('faq-content')\"\u003eCheck our FAQs for more information\u003c\/a\u003e\u003c\/p\u003e\n\u003cdiv class=\"expandable\" id=\"faq-content\"\u003e\n\u003ch3 class=\"section-title\"\u003eFAQs\u003c\/h3\u003e\n\u003cdiv\u003e\n\u003cp\u003e\u003cstrong\u003eWhat breeds are affected by PSSM1 and WFFS?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 affects many breeds, including Quarter Horses, Belgian Draft Horses, and Warmbloods. WFFS primarily affects Warmbloods but has also been detected in breeds like Thoroughbreds, Knabstruppers, Haflingers, and American Sport Ponies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow are PSSM1 and WFFS inherited?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 is inherited in an autosomal dominant manner, meaning horses with one (n\/P1) or two (P1\/P1) copies of the mutated gene can develop the disease. WFFS is inherited as an autosomal recessive trait, requiring two copies of the mutated gene (WFFS\/WFFS) for the disease to manifest. Affected foals with two copies of the WFFS mutation will not survive to adulthood and must be euthanized shortly after birth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow can PSSM1 and WFFS be managed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePSSM1 management includes dietary modifications to reduce starch and sugar intake, and a consistent exercise regimen. WFFS, however, is a lethal condition with no cure, emphasizing the importance of genetic testing to inform breeding decisions and avoid producing affected foals.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/equigerminal.shop\/pages\/faqs\" target=\"_blank\"\u003eVisit our full FAQ page\u003c\/a\u003e for more details.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Equigerminal","offers":[{"title":"Default Title","offer_id":41990960906390,"sku":"","price":73.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/files\/FFSPSSM1.png?v=1711469296"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2726\/7968\/collections\/Discover_your_animal_heart_health_32.png?v=1782467179","url":"https:\/\/www.equigerminal.org\/tr\/collections\/performance-wellness.oembed","provider":"Equigerminal","version":"1.0","type":"link"}