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Perfil de color de la capa

Name: Perfil de color de la capa
Brand: Equigerminal
Price: 150.0 EUR

8 paneles de ADN perfil de color con resultados en 5 días laborables. Incluye 8 marcadores genéticos del color del pelaje: 2 colores base - Agouti,...

€150.00 BEZa barne

Acerca de la prueba

Prueba genética de 8 paneles para color de pelaje con resultados en 5 a 10 días hábiles.

Incluye 8 marcadores genéticos de color de pelaje:

Color base (2):

Agouti
Extensión

Diluciones (5):

Crema
Perla
Champán
Plata
Dun (D, nd1, nd2)

Despigmintación (1):

Gris* (G/G, G/N o N/N)

Nuestra prueba de Gris en paneles proporciona el número de copias del gen Gris (G/G, G/N o N/N).

Un Certificado Genético de Color – Genotipo del Pelaje y Predicción del Color del Pelaje en la Descendencia es proporcionado.

¿Por qué probar?

Las pruebas de ADN para pelajes pueden ser una herramienta importante para la selección, eliminación de enfermedades relacionadas con el pelaje y para mejorar tu criadero.

La determinación genética del color del pelaje permite identificar con precisión el genotipo del pelaje del caballo y ayuda a predecir la posible transmisión del color del pelaje a la descendencia.

Signos clínicos

How the eight results build a colour:

Extension and Agouti give the base: chestnut, bay or black
Cream gives palomino, buckskin or smoky black with one copy, and cremello, perlino or smoky cream with two
Pearl, when it shows, looks much like a double cream
Champagne gives gold, amber and classic champagne
Silver lightens black pigment and the mane and tail, so it shows on bays and blacks
Dun lightens the body and adds a dorsal stripe and leg bars. An nd1 horse can have a stripe without the lightening
Grey sits on top of everything: the horse is born with its colour and turns white with age

Health. Silver also causes an eye disorder, Multiple Congenital Ocular Anomalies (MCOA): horses with two copies have the severe form and horses with one copy the milder form. Grey horses develop skin melanomas far more often than other horses. The other genes in this panel have no known disease link. The panel does not diagnose disease; your veterinarian does.

Transmisión

Each of the eight genes is inherited separately: a foal gets one copy of each gene from each parent, by chance. None is on a sex chromosome, so colts and fillies are the same.

How each gene shows:

Extension: chestnut needs two e copies
Agouti: black needs two a copies
Cream: one copy shows, two copies show more
Pearl: needs two copies, or one Pearl with one Cream
Champagne, Silver, Dun and Grey: one copy is enough

Prevención

With all eight genes known, you can plan matings for the colours you want, and against the ones you do not.

To be sure of a colour, look for a parent with two copies of it: a cremello always passes on Cream, and a horse with two Grey copies always passes on Grey
To avoid a surprise colour, check that neither parent is a hidden carrier
To avoid the severe Silver eye form, do not mate two Silver carriers
Have a horse that carries Silver examined by a veterinary eye specialist
For grey horses, ask your veterinarian to include skin checks for melanoma at routine visits

Colour should not be the only thing that decides a mating.

Resultados

Un Certificado Genético de Color se proporciona, incluyendo:

Genotipo del pelaje.
Predicción del color del pelaje de la descendencia. Estado del gen gris (G/G, G/N o N/N).

Requisitos de muestra

30 a 40 raíces capilares o 5 mL de sangre (tubo K3 EDTA)

Envía tu muestra por correo ordinario o entrega exprés a:

Laboratorio Equigerminal HIESE
Rua da Quinta do Sobreiro Nº25
3230-343 Penela, Portugal

Tiempo de entrega

De 5 a 10 días hábiles

Cómo funciona

🛒 Purchase the test: select and buy the test online.

📧 Receive instructions: after payment confirmation you receive sample collection instructions by e-mail.

✨ Collect the sample yourself: pull 20 to 40 hair roots with the bulb attached, or ask your veterinarian to collect blood in a K3-EDTA tube.

📄 Complete the form: print and complete the submission form with the animal identification.

📮 Send it to the laboratory: Equigerminal, S.A., HIESE, Rua da Quinta do Sobreiro, 25, Quinta Vale do Espinhal, 3230-343 Penela, PORTUGAL.

📄 Receive your report: your certified report is issued as soon as the analysis is validated.

Preguntas frecuentes

What does this panel not detect?
White patterns (tobiano, frame overo, leopard complex, sabino, splashed white, dominant white), roan, Mushroom, the rarer Cream-gene dilutions Sunshine and Snowdrop, sooty and flaxen. Tobiano, frame overo, leopard complex and PATN1 have their own tests; the others need their own tests or have no test yet.

Should I order the panel or single tests?
The panel reads all eight genes and works out the colour from them together. If you only need one or two genes, the single tests cover them.

At what age can a horse be tested?
Any age. The result never changes, and foal coats are a poor guide to the adult colour, so testing early is worthwhile.

For Professionals

Genetic and clinical detail for veterinarians, geneticists and laboratories.

Loci genotyped (gene, variant, inheritance). Full HGVS, identifiers, classification, frequencies and references are on each individual test page.

Extension: MC1R (ECA3) · e, NM_001114534.1:c.248C>T, p.(Ser83Phe) · autosomal recessive (chestnut). e^a not read.
Agouti: ASIP (ECA22) · a, NM_001164017.1:c.187_197del (published c.191_201del) · autosomal recessive (black).
Cream: SLC45A2 (ECA21) · C^Cr, XM_001498110.4:c.601G>A, p.(Asp201Asn) (published c.457G>A, p.Asp153Asn) · autosomal incomplete dominant.
Pearl: SLC45A2 (ECA21) · C^prl, XM_001498110.4:c.1129G>A, p.(Ala377Thr) (published c.985G>A, p.Ala329Thr) · autosomal recessive; dilutes with one copy in combination with Cream.
Champagne: SLC36A1 (ECA14) · Ch, XM_023617382.1:c.188C>G, p.(Thr63Arg) · autosomal dominant.
Silver: PMEL (ECA6) · Z, NM_001163889.1:c.1849C>T, p.(Arg617Cys) (published R618C; also R625C) · autosomal dominant (coat); autosomal co-dominant for Multiple Congenital Ocular Anomalies.
Dun: TBX3 (ECA8) · D, nd1, nd2, regulatory structural variants (nd2 = reference EquCab3.0, about 1.6 kb deletion) · autosomal dominant, D > nd1 > nd2.
Grey: STX17 (ECA25) · 4.6 kb intronic copy-number variant, NC_009168.3:g.6625295_6629872dup (G2) / [3] (G3); G2 and G3 not distinguished · autosomal dominant.

Breeds: Extension and Agouti vary in every breed. Cream was found in 25 of 28 breeds tested (Avila et al., 2022). Pearl occurs mainly in Iberian and stock-horse breeds. Champagne occurs in breeds such as the Miniature Horse, Tennessee Walking Horse and Missouri Fox Trotter. Grey has been found in at least 62 breeds and populations.

Key references:

Marklund L, Moller MJ, Sandberg K, Andersson L (1996). Mamm Genome 7:895-899. PMID 8995760.
Rieder S, Taourit S, Mariat D, Langlois B, Guerin G (2001). Mamm Genome 12:450-455. doi:10.1007/s003350020017. PMID 11353392.
Mariat D, Taourit S, Guerin G (2003). Genet Sel Evol 35:119-133. doi:10.1051/gse:2002039. PMID 12605854.
Sevane N, Sanz CR, Dunner S (2019). Anim Genet 50:275-278. doi:10.1111/age.12784. PMID 30968968.
Cook D, Brooks S, Bellone R, Bailey E (2008). PLoS Genet 4:e1000195. doi:10.1371/journal.pgen.1000195. PMID 18802473.
Brunberg E, Andersson L, Cothran G, Sandberg K, Mikko S, Lindgren G (2006). BMC Genet 7:46. doi:10.1186/1471-2156-7-46. PMID 17029645.
Imsland F, McGowan K, Rubin CJ, et al. (2016). Nat Genet 48:152-158. doi:10.1038/ng.3475. PMID 26691985.
Rosengren Pielberg G, Golovko A, Sundstrom E, et al. (2008). Nat Genet 40:1004-1009. doi:10.1038/ng.185. PMID 18641652.