Productformulier

Bornavirus, RT-qPCR

Name: Bornavirus, RT-qPCR
Brand: Equigerminal
Price: 61.5 EUR

De RT-cPCR-test detecteert het genoom (RNA) van het Borna-virus. Monster 5 ml - bloed - K3-EDTA-buis en/of 5 ml - liquor...

€61.50 Incl. BTW

Over

The RT-cPCR test detects the genome (RNA) of Borna virus.

What is Borna virus?

Borna disease is caused by one of just a few bornaviruses that occur in a wide variety of warm-blooded animals.

This virus attacks the nerve cells within the brain itself causing dangerous levels of inflammation.

This virus is frequently lethal once symptoms begin presenting themselves, however, antibodies specific to the virus have frequently been found in the blood of animals who are clinically unaffected. This suggests that some horses and other animals may become infected and remain asymptomatic.

Borna disease is a rare viral infection that causes swelling of the nerve cells in the brain, leading to unusual behaviours and seizures, and is frequently fatal.

Klinische tekenen

The clinical signs of Borna disease usually occur in horses two to three months after the initial exposure, although there have been reports of incubation periods exceeding six months.

Blindness
Chewing motions
Colic symptoms
Collapse
Head-pressing
Hypersensitivity
Lack of coordination
Leaning
Loss of appetite
Muscular tremors
Paralysis
Rapid and involuntary eye movement
Sawhorse stance
Severe depression
Weakness
Yawning

Transmissie

The virus that causes Borna disease in horses is closely related to the bornavirus that affects birds and is believed to be the cause of Proventricular Dilatation Disease (PDD) in birds.

The transmission methods for these viruses are not well understood, but direct contact with either saliva or nasal secretions are believed to be a common vector.

Borna disease emerges more frequently on farms with poor rodent control and hygiene, and instances seem to peak during the months between March and June.

Preventie

Experimental vaccines for immunopathology have had mixed results. In some cases, the immunopathology of the infection caused some vaccines to exacerbate the disease, but recent evidence suggests the possibility of effective inoculation.

Although some preliminary research indicates success with protective vaccination of mice, at this writing, no pre-exposure vaccine has been developed for use with horses.

Voorbeeld

5 mL - blood - K3 EDTA tube and/or 5 mL - liquor (CSF) - sterile tube

Doorlooptijd

2 to 5 working days

Hoe het werkt

🛒 Koop de test: kies de test en koop hem online.

📧 Ontvang de instructies: na bevestiging van de betaling ontvangt u de instructies voor het afnemen van het monster per e-mail.

📄 Vul het formulier in: print het inzendformulier en vul het in met de identificatie van het dier.

✨ Neem het monster af: trek 20 tot 40 haren met wortel (bulbus) uit en plak ze in het gemarkeerde vak op het formulier, of laat uw dierenarts bloed afnemen in een K3-EDTA-buis.

📮 Stuur het naar het laboratorium: Equigerminal, S.A., HIESE, Rua da Quinta do Sobreiro, 25, Quinta Vale do Espinhal, 3230-343 Penela, PORTUGAL.

📊 Ontvang het rapport: het gecertificeerde rapport wordt uitgegeven zodra de analyse is gevalideerd.

Veelgestelde vragen

Who collects the sample? Your veterinarian. See Sample for the material and the volume this test requires.

How should the sample be sent? Keep it cool and send it by tracked courier as soon as it is collected. Shipping is arranged and paid for by the client.

What happens if the sample arrives unsuitable? We contact you before processing and ask for a new sample.

Can other tests be added to the same sample? Often yes, if the material and the volume allow it. Ask us before shipping.

How long does it take? See Turnaround. The count starts when the sample arrives at the laboratory, not when you order.

Meer

The antiviral drug amantadine sulfate may be a potential treatment for Borna disease virus. It has been demonstrated in vitro to inhibit wild-type BDV replication and spread of infection.

As with prevention of the disease, much research is needed to develop successful treatment strategies because, currently, the fatality rate ranges between 60 to 95 percent for horses, and animals that survive often remain neurologically impaired permanently.