Productformulier

Test op verwachte schofthoogte, LCORL/NCAPG

Name: Test op verwachte schofthoogte, LCORL/NCAPG
Brand: Equigerminal
Price: 62.73 EUR

DNA-testkit DNA-test om het genetische potentieel te voorspellen voor een paard met een kleine, gemiddelde of grote schofthoogte. Monster...

€62.73 Incl. BTW

Over

This test shows whether your horse is genetically inclined to be taller or smaller than others of its breed. It reads one DNA marker linked to adult height.

It is meant for breeders planning for size, including Warmblood breeders.

Waarom testen?

Breeding for size. Knowing the result of both parents tells you the chances for each foal before the mating.

An early indication for a foal. A foal can be tested at birth, years before it reaches its adult height. The result never changes.

Understanding a stallion or mare. The result shows what the horse can pass on for size.

Klinische tekenen

Height is a trait, not a disease. No disease is linked to this marker.

A T/T Warmblood and a T/T pony are not the same size.

Transmissie

Each copy counts. Neither version hides the other: one C copy gives part of the effect, two give more. The marker is not on a sex chromosome, so colts and fillies are the same.

What each mating can produce:

T/T x T/T gives 100% T/T
T/T x T/C gives 50% T/T, 50% T/C
T/T x C/C gives 100% T/C
T/C x T/C gives 25% T/T, 50% T/C, 25% C/C
T/C x C/C gives 50% T/C, 50% C/C
C/C x C/C gives 100% C/C

Preventie

The result helps you plan matings for size.

To raise the chance of a taller foal, choose a parent with two copies of the tall version
To keep size down, use parents that both carry only the small version

Height should not be the only thing that decides a mating. Health, conformation and temperament are not read here.

Resultaten

T/T: two copies of the small version. The horse tends to be smaller.

T/C: one copy of each. The horse tends to be in between.

C/C: two copies of the tall version. The horse tends to be taller.

The report is a DNA certificate that identifies the horse and the genotype found.

Voorbeeld

Hair roots: 20 to 40 hairs pulled (not cut) from the mane or tail, with the roots attached. Tape them inside the marked area of the printable sample submission form. Hairs without roots cannot be analysed. For a young foal, tail hair is usually easiest.

Blood: 5 mL of whole blood in a K3-EDTA tube, collected by a veterinarian. Label the tube with the horse's name and send it with the submission form.

Keep samples dry and at room temperature, and do not freeze them. Do not send hair that is wet, mouldy or soiled with bedding or faeces.

Doorlooptijd

Standard processing: results within 5 to 10 working days of the sample arriving at the laboratory. Shipping is arranged and paid for by the client, and transit time is not included in the 5 to 10 working days.

Samples that fail DNA extraction or amplification are repeated at no extra cost, which may add a few working days. We contact you if a new sample is required.

Hoe het werkt

🛒 Koop de test: kies de test en koop hem online.

📧 Ontvang de instructies: na bevestiging van de betaling ontvangt u de instructies voor het afnemen van het monster per e-mail.

📄 Vul het formulier in: print het inzendformulier en vul het in met de identificatie van het dier.

✨ Neem het monster af: trek 20 tot 40 haren met wortel (bulbus) uit en plak ze in het gemarkeerde vak op het formulier, of laat uw dierenarts bloed afnemen in een K3-EDTA-buis.

📮 Stuur het naar het laboratorium: Equigerminal, S.A., HIESE, Rua da Quinta do Sobreiro, 25, Quinta Vale do Espinhal, 3230-343 Penela, PORTUGAL.

📊 Ontvang het rapport: het gecertificeerde rapport wordt uitgegeven zodra de analyse is gevalideerd.

Veelgestelde vragen

Can this test predict my foal's exact adult height?
No. Many other genes also count, and feeding and health care during growth matter as much as the genotype. The same genotype gives very different heights in different breeds, and we found no published study that supports fixed heights for each genotype across breeds. That is why the report gives no height in centimetres.

For Professionals

Genetic and clinical detail for veterinarians, geneticists and laboratories.

Gene / locus: LCORL/NCAPG region, ECA3; intergenic marker upstream of LCORL (ligand dependent nuclear receptor corepressor like). Evidence favours LCORL as the effector gene; NCAPG was ruled out as the candidate (Metzger et al., 2013).
Variant: SNP BIEC2-808543, T/C; C associated with greater withers height and reduced LCORL expression (40% lower in T/C and 56% lower in C/C than in T/T). Proposed to disrupt a regulatory element; causality not established. No HGVS description is available in our sources.
Variant identifiers: rs68603064.
Variant classification: no OMIA entry (quantitative trait marker, not in the OMIA variant table, dump of 2026-09-19); no ISAG/AVCG classification.
Inheritance: additive quantitative trait locus; each C copy adds to the effect.
Effect size: the region explained about 18% of the variance in withers height in German Warmbloods (Tetens et al., 2013). In Franches-Montagnes horses each C copy added about 1 cm to the breeding value for withers height (Signer-Hasler et al., 2012).
Breeds studied: association with withers height reported in German Warmbloods (Tetens et al., 2013; Metzger et al., 2013) and in a multi-breed GWAS including Franches-Montagnes horses (Signer-Hasler et al., 2012). Metzger et al. (2013) studied Hanoverians and other German Warmbloods, Oldenburgs, Holsteiners, Westphalians, Lusitanos, Arabians and ponies. Almost all ponies tested so far are T/T.
Allele / carrier frequencies: genotype frequencies T/T, T/C, C/C (Metzger et al., 2013): Arabian (n=223) 100%, 0%, 0%; Lusitano (n=96) 67%, 29%, 4%; Hanoverian (n=590) 16%, 56%, 28%; Oldenburg (n=21) 14%, 57%, 29%; Holsteiner (n=11) 18%, 64%, 18%; Westphalian (n=45) 9%, 60%, 31%. Oldenburg and Holsteiner samples are very small.
Clinical notes for veterinarians: other size loci (for example HMGA2, ZFAT) are not assessed. Not informative in breeds fixed for T/T.

Key references:

Metzger J, Schrimpf R, Philipp U, Distl O (2013). Expression levels of LCORL are associated with body size in horses. PLoS One 8:e56497.
Signer-Hasler H, Flury C, Haase B, et al. (2012). A genome-wide association study reveals loci influencing height and other conformation traits in horses. PLoS One 7:e37282.
Tetens J, Widmann P, Kuhn C, Thaller G (2013). A genome-wide association study indicates LCORL/NCAPG as a candidate locus for withers height in German Warmblood horses. Anim Genet 44:467-471.